1.
Ann Rheum Dis
; 81(11): e230, 2022 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32988840
2.
Eur J Intern Med
; 74: 119-120, 2020 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32014365
3.
Arthritis Rheumatol
; 72(6): 1038, 2020 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31994338
4.
Indian J Pharmacol
; 48(1): 86-7, 2016.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26997730
RESUMO
Various mechanisms contribute to anemia in inflammatory bowel diseases (IBD), drug-related causes being less frequent. The hematological and other adverse events of azathioprine (AZA) therapy are well documented, but drug-associated pure red cell aplasia (PRCA) is an uncommon event. We hereby describe two cases of AZA-associated PRCA in patients with Crohn's disease. The diagnosis was supported by pathological reports, and prompt hematological recovery was seen with discontinuation of the offending drug. This report highlights the need to consider this rare entity in IBD patients in appropriate settings and for adopting adequate precautionary measures.