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Comput Biol Med ; 172: 108256, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38489989

RESUMO

Sepsis, a life-threatening condition triggered by the body's response to infection, presents a significant global healthcare challenge characterized by disarrayed host responses, widespread inflammation, organ impairment, and heightened mortality rates. This study introduces the ncRS database (http://www.ncrdb.cn), a meticulously curated repository housing 1144 experimentally validated non-coding RNAs (ncRNAs) intricately linked with sepsis. ncRS offers comprehensive RNA data, exhaustive experimental insights, and integrated annotations from diverse databases. This resource empowers researchers and clinicians to decipher ncRNAs' roles in sepsis pathogenesis, potentially identifying vital biomarkers for early diagnosis and prognosis, thus facilitating personalized treatments.


Assuntos
RNA não Traduzido , Sepse , Humanos , RNA não Traduzido/genética , Bases de Dados de Ácidos Nucleicos , Biomarcadores , Sepse/genética
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