Detection of functional connectivity in the brain during visuo-guided grip force tracking tasks: A functional near-infrared spectroscopy study.

The functional connectivity (FC) between multiple brain regions during tasks is currently gradually being explored with functional near-infrared spectroscopy (fNIRS). However, the FC present during grip force tracking tasks performed under visual feedback remains unclear. In the present study, we used fNIRS to measure brain activity during resting states and grip force tracking tasks at 25%, 50%, and 75% of maximum voluntary contraction (MVC) in 11 healthy subjects, and the activity was measured from four target brain regions: the left prefrontal cortex (lPFC), right prefrontal cortex (rPFC), left sensorimotor cortex (lSMC), and right sensorimotor cortex (rSMC). We determined the FC between these regions utilizing three different methods: Pearson's correlation method, partial correlation method, and a pairwise maximum entropy model (MEM). The results showed that the FC of lSMC-rSMC and lPFC-rPFC (interhemispheric homologous pairs) were significantly stronger than those of other brain region pairs. Moreover, FC of lPFC-rPFC was strengthened during the 75% MVC task compared to the other task states and the resting states. The FC of lSMC-lPFC and rSMC-rPFC (intrahemispheric region pairs) strengthened with a higher task load. The results provided new insights into the FC between brain regions during visuo-guided grip force tracking tasks.

The Effect of Visual Stimuli on Stability and Complexity of Postural Control.

Visual input could benefit balance control or increase postural sway, and it is far from fully understanding the effect of visual stimuli on postural stability and its underlying mechanism. In this study, the effect of different visual inputs on stability and complexity of postural control was examined by analyzing the mean velocity (MV), SD, and fuzzy approximate entropy (fApEn) of the center of pressure (COP) signal during quiet upright standing. We designed five visual exposure conditions: eyes-closed, eyes-open (EO), and three virtual reality (VR) scenes (VR1-VR3). The VR scenes were a limited field view of an optokinetic drum rotating around yaw (VR1), pitch (VR2), and roll (VR3) axes, respectively. Sixteen healthy subjects were involved in the experiment, and their COP trajectories were assessed from the force plate data. MV, SD, and fApEn of the COP in anterior-posterior (AP), medial-lateral (ML) directions were calculated. Two-way analysis of variance with repeated measures was conducted to test the statistical significance. We found that all the three parameters obtained the lowest values in the EO condition, and highest in the VR3 condition. We also found that the active neuromuscular intervention, indicated by fApEn, in response to changing the visual exposure conditions were more adaptive in AP direction, and the stability, indicated by SD, in ML direction reflected the changes of visual scenes. MV was found to capture both instability and active neuromuscular control dynamics. It seemed that the three parameters provided compensatory information about the postural control in the immersive virtual environment.

Chiral symmetry breaking in a reaction-diffusion system.

The emergence of order in far-from-equilibrium systems is often accompanied by the formation of spatially asymmetric patterns. About 30 years ago, a general mechanism to select a chiral solution by coupling a reaction-diffusion system to an external chiral electric field was proposed by Nicolis and Prigogine [Proc. Natl. Acad. Sci. USA 78, 659 (1981)]. However, no experimental or even numerical evidence in reaction-diffusion systems has been reported yet. Here we report a chiral symmetry-breaking phenomenon in a reaction-diffusion system coupled to a circularly polarized electric field (CPEF). Specifically, we show that the CPEF breaks the zero-rotation chiral symmetry between clockwise and counterclockwise spiral defects and that ordered spiral waves with preferred chirality arise from defect-mediated turbulence. The occurrence of such chiral symmetry breaking can be understood by the competition between spiral defects with opposite chirality.

Resonant drift of two-armed spirals by a periodic advective field and periodic modulation of excitability.

The drift behavior of two-armed spirals induced by periodic advective field and periodic modulation of excitability is investigated. It is shown that the two-armed spirals controlled by periodic advective field and periodic modulation of excitability drift in completely different ways. For periodic advective field, the two tips of the two-armed spiral drift in the same direction and the two-armed spiral is stable. While for periodic modulation of excitability, the two tips drift in the opposite direction and the two-armed spiral splits into two single-armed spirals. Analytical results based on a kinematic theory of rotating spirals in weakly excitable media are consistent with the numerical results.

Stabilization of multiarmed spiral waves by circularly polarized electric fields.

The influence of circularly polarized electric fields (CPEFs) on the stability of multiarmed spiral waves is investigated. It is shown that CPEFs can change the period of the multiarmed spirals. The average period is an important quantity of multiarmed spiral and it must be larger than a threshold for stable multiarmed spiral. After a counter-rotating CPEF with suitable amplitude and period is applied, the average period of the multiarmed spiral may increase, which stabilizes the multiarmed spiral.