RESUMO
The two co-authors of the mentioned above article were incorrect. The correct are authors should have been "P. A. Beltrán" instead of "P. A. B. Roa" and "J. F. Diaz-Coto" instead of "L. Diaz Soto".
Assuntos
Anticorpos Monoclonais/uso terapêutico , Antirreumáticos/uso terapêutico , Artrite Reumatoide/tratamento farmacológico , Algoritmos , Anticorpos Monoclonais/administração & dosagem , Anticorpos Monoclonais Murinos , Antirreumáticos/administração & dosagem , Contraindicações , Esquema de Medicação , Humanos , América Latina , Seleção de Pacientes , Rituximab , Resultado do TratamentoRESUMO
Central nervous system compromise is a major cause of morbidity and mortality in SLE. The clinical picture of cerebral cryptococcosis is non-specific and can be mistaken for lupic activity. A retrospective study was undertaken with 10 patients with SLE and cryptococcal meningitis compiled in a 23-year period. The most common symptoms were fever and headache. Lymphocyte counts ranged from 169 to 912 cells/mm. An average delay of 13.6 days in diagnosis was observed in patients with cryptococcal meningitis with no complications and an average delay of 52.4 days in patients with complications. Low lymphocyte counts, observed in all patients, was considered a possible risk factor for cerebral cryptococcosis. To note the association between the delay in the correct diagnosis and complications derived from cerebral cryptococcosis.
Assuntos
Lúpus Eritematoso Sistêmico/complicações , Meningite Criptocócica/complicações , Adolescente , Adulto , Feminino , Humanos , Masculino , Meningite Criptocócica/diagnóstico , Pessoa de Meia-Idade , Estudos RetrospectivosRESUMO
The case of a 35 years old female patient is here reported. Her previous medical records included repeated miscarriages and ischaemic ulcers in the right leg. She developed thrombosis at the left common femoral artery with serum antiphospholipid antibodies. The patient was treated with anticoagulants and two months later developed multiorganic failure. She was successfully managed with plasmapheresis, high dose prednisone, and anticoagulants. The clinical picture was considered to be a catastrophic antiphospholipid syndrome.