Assuntos
Complicações na Gravidez/epidemiologia , Fumar/epidemiologia , Bases de Dados Factuais , Feminino , Humanos , Avaliação das Necessidades , Nova Escócia/epidemiologia , Vigilância da População , Gravidez , Complicações na Gravidez/prevenção & controle , Prevalência , Estudos Prospectivos , Abandono do Hábito de Fumar , Prevenção do Hábito de FumarRESUMO
OBJECTIVE: Weight change between pregnancies was examined to determine if there were an association between weight gain (or loss) and delivery by cesarean section, gestational diabetes or pregnancy-induced hypertension. METHODS: A cohort study was conducted which included Nova Scotia residents with two or more singleton deliveries between 1988 and 1996. Weight change between pregnancies was calculated as the difference in weight from a woman's initial pre-pregnancy weight and the pre-pregnancy weight recorded from her final recorded pregnancy. RESULTS: Weight change between pregnancies was examined in 19,932 women. Women in the highest weight gain category were at an increased risk for developing gestational diabetes (RR = 1.59, 95% CI 1.22-2.08), independent of their weight prior to the final pregnancy, and other confounders. Weight gain (or loss) between pregnancies was not associated with the other outcomes. INTERPRETATION: Weight gain between pregnancy is an independent risk factor for gestational diabetes.
Assuntos
Resultado da Gravidez/epidemiologia , Aumento de Peso , Redução de Peso , Cesárea/estatística & dados numéricos , Estudos de Coortes , Diabetes Gestacional/epidemiologia , Diabetes Gestacional/etiologia , Feminino , Humanos , Hipertensão/epidemiologia , Hipertensão/etiologia , Nova Escócia/epidemiologia , Vigilância da População , Gravidez , Complicações Cardiovasculares na Gravidez/epidemiologia , Complicações Cardiovasculares na Gravidez/etiologia , Estudos Retrospectivos , Fatores de RiscoRESUMO
A case-control study has been conducted to determine the association between employment as a fire fighter and congenital heart defects among the offspring. Cases were fathers of all children born between 1979 and 1986 in Ontario, Canada, who were diagnosed with a cardiac congenital anomaly during the first year of life (n = 9340). Matched controls (n = 9340), defined as fathers whose child did not have a congenital anomaly, were randomly selected from the Ontario birth certificate file. In order to identify those fathers who had been employed as a fire fighter, the cases and controls were linked to a cohort of Metropolitan Toronto fire fighters. Eleven cases and nine controls worked as fire fighters, giving an odds ratio of 1.22 (95 percent confidence interval 0.46-3.33). This study had sufficient power to detect the level of risk reported in one previous study; however, these results do not support a hypothesis of elevated risk of cardiac congenital anomalies among the offspring of fire fighters.