[Evaluation of the role of dietary intake in the occurrence of alopecia]. / Evaluation du rôle des apports alimentaires dans la survenue d'une alopécie diffuse.

Transversal case-control study was conducted among 42 patients aged between 20 and 35 years who had diffuse alopecia. Alimentary inquiry according to the 3-day method was achieved in each case. The following nutriments were evaluated: total proteins, calcium, copper, iron, iodine, magnesium, manganese, phosphorus, potassium, selenium, zinc, omega 3 and omega 6. A control group (composed of 230 individuals), matched for age, gender and metabolic profile was established. These persons did not suffer from hair and nail disorder. The nutriments were codified according to the data of the software Food processor 8.3 version. The data were analyzed using "SPSS" 11.5 version. Comparisons of the means were performed using the Student's t test. ROC graphics allowed to determine the statistically significative limits for the comparison of both groups. On multivariate analysis, only a protein intake was directly associated to alopecia, odds ratio of 1,5 (1,06 - 2,3) p=0,02.

[Prevalence of conventional cardiovascular risk factors in the Great Tunis population]. / Prévalence des facteurs de risque cardiovasculaires conventionnels dans la population du Grand Tunis.

BACKGROUND: This study was designed to determine the prevalence of main cardiovascular risk factors in the population of Great Tunis. SUBJECTS AND METHODS: This cross-sectional study included 2483 individuals aged 35 to 70 years dwelling in the Great Tunis region, recruited between March 2004 and June 2005. The sample was weighted using the inverse of response rate according to governorate, district and sex. RESULTS: Obesity and abdominal obesity were observed respectively in 34 and 48% of subjects. The prevalence of these two factors was particularly elevated in females (46 and 69% respectively). Hypertension was common (31%), especially in women (36%). Diabetes mellitus and dyslipemia were found in 15 and 21% of subjects, respectively, without difference according to sex. More than half of men and 8% of women were current smokers. CONCLUSION: The prevalence of conventional cardiovascular risk factors is dramatically high in the population of Great Tunis. These findings predict a future expansion of cardiovascular diseases in this population. Profound changes of lifestyle and dietary habits of Tunisians are needed to reduce the risk of cardiovascular morbidity and mortality.

Prevalence of obesity and associated socioeconomic factors among Tunisian women from different living environments.

Adult Tunisian women aged 20-59 (national random sample, n = 1849), were assessed with respect to environmental and socioeconomic factors associated with obesity (body mass index >or=30 kg m(-2)) and abdominal obesity (waist circumference >or=88 cm). At the national level, prevalence of obesity and abdominal obesity were, respectively, 22.6% and 29.2%, but varied markedly (both P < 0.0001) among living environments classified as big cities (30.2% and 36.6%), other cities (25.9% and 32.4%), rural clustered (19.4% and 24.8%) and rural dispersed (9.5% and 16.5%). Adjusted prevalences of both types of obesity increased with age, parity and economic level of the household, while educationally, the risk was greatest in women with intermediate schooling. Differences between the four environments were accounted for by socioeconomic factors, mostly household wealth, except for most rural environment; socio-cultural factors were possibly influential. Observed differences between rural areas confirmed that finer measures of urbanization are necessary for the drivers of obesity prevalence at the national level. Obesity was still more prevalent in wealthy than in poor women, but given the high prevalence in all the environments, actions are needed at the national level before highly prevalent obesity extends into those of lower socioeconomic status and thereby increases health inequities.

Relationships between threshold-based PROP sensitivity and food preferences of Tunisians.

The extent to which taste responses--and notably the genetically determined sensitivity to 6-n-propylthiouracil (PROP)--influences food preferences and food use is still a matter of debate. We addressed the issue on the basis of a behavioural and anthropological study performed in Tunis in 1999. The working sample consists of 123 adults of both sexes (38 men, 85 women), aged 19-59, in various social categories. Taste recognition thresholds for sucrose, fructose, sodium chloride, quinine hydrochloride, citric acid, tannic acid, oak tannin and PROP were determined by presenting, in a semi-randomised order (blind-test), series of graded aqueous solutions of each product. Subjects also tasted and rated the pleasantness/unpleasantness of 4 supra-threshold solutions of NaCl and sucrose. All subjects completed a checklist of 43 food items representative of Tunisian diet, rated in terms of flavour, cost, effect on health and prestige on a labelled affective magnitude scale. According to the underlying distribution of PROP thresholds, the subjects were separated into three categories: "non-tasters", "medium-threshold tasters", and "low-threshold tasters". Results bring out the specificity of low-threshold tasters, as exhibiting a greater taste sensitivity for most tested substances. Low-threshold taster status is also linked to higher mean food preferences ratings irrespective of sex, age and socio-cultural influences. Tasters as a group (medium-threshold tasters + low-threshold tasters) do not exhibit a higher percentage of food dislikes; however PROP sensitivity is negatively correlated with hedonic responses to NaCl solutions. These results together with the evidence of a limited set of food actually used by low-threshold tasters suggest that these subjects might have difficulties at overcoming an inherent neophobia.

Increased fat oxidation during Ramadan fasting in healthy women: an adaptative mechanism for body-weight maintenance.

Possible effects of Ramadan fasting on anthropometric and metabolic variables were investigated in healthy Tunisian Moslem women. Total daily energy intake remained unchanged whereas the qualitative components of nutrients were markedly affected. Neither body weight nor body composition were influenced by Ramadan fasting. Results also indicate the concomitant decrease of plasma insulin concentrations with respiratory and energy expenditure during Ramadan. The circadian evolution of nutrient oxidation rates was modified. Fat oxidation was increased and carbohydrate oxidation was decreased during the light span of the nycthemeron. Qualitative and quantitative circadian changes in feeding associated with Ramadan might be counterbalanced by specific metabolic changes in order to preserve normal body weight and composition.