RESUMO
PURPOSE: The specific aim of this project was to quantify knee forces and muscle activity while performing squat and leg press exercises with technique variations. METHODS: Ten experienced male lifters performed the squat, a high foot placement leg press (LPH), and a low foot placement leg press (LPL) employing a wide stance (WS), narrow stance (NS), and two foot angle positions (feet straight and feet turned out 30 degrees ). RESULTS: No differences were found in muscle activity or knee forces between foot angle variations. The squat generated greater quadriceps and hamstrings activity than the LPH and LPL, the WS-LPH generated greater hamstrings activity than the NS-LPH, whereas the NS squat produced greater gastrocnemius activity than the WS squat. No ACL forces were produced for any exercise variation. Tibiofemoral (TF) compressive forces, PCL tensile forces, and patellofemoral (PF) compressive forces were generally greater in the squat than the LPH and LPL, and there were no differences in knee forces between the LPH and LPL. For all exercises, the WS generated greater PCL tensile forces than the NS, the NS produced greater TF and PF compressive forces than the WS during the LPH and LPL, whereas the WS generated greater TF and PF compressive forces than the NS during the squat. For all exercises, muscle activity and knee forces were generally greater in the knee extending phase than the knee flexing phase. CONCLUSIONS: The greater muscle activity and knee forces in the squat compared with the LPL and LPH implies the squat may be more effective in muscle development but should be used cautiously in those with PCL and PF disorders, especially at greater knee flexion angles. Because all forces increased with knee flexion, training within the functional 0-50 degrees range may be efficacious for those whose goal is to minimize knee forces. The lack of ACL forces implies that all exercises may be effective during ACL rehabilitation.
Assuntos
Traumatismos do Joelho/reabilitação , Articulação do Joelho/fisiologia , Levantamento de Peso/fisiologia , Adulto , Ligamento Cruzado Anterior/fisiologia , Lesões do Ligamento Cruzado Anterior , Fenômenos Biomecânicos , Humanos , Masculino , Músculo Esquelético/fisiologia , Ligamento Cruzado Posterior/lesões , Ligamento Cruzado Posterior/fisiologia , Postura , Suporte de CargaRESUMO
The aim of this study was to compare and evaluate the kinematics of baseball pitchers who participated in the 1996 XXVI Centennial Olympic Games. Two synchronized video cameras operating at 120 Hz were used to video 48 pitchers from Australia, Japan, the Netherlands, Cuba, Italy, Korea, Nicaragua and the USA. All pitchers were analysed while throwing the fastball pitch. Twenty-one kinematic parameters were measured at lead foot contact, during the arm cocking and arm acceleration phases, and at the instant of ball release. These parameters included stride length, foot angle and foot placement; shoulder abduction, shoulder horizontal adduction and shoulder external rotation; knee and elbow flexion; upper torso, shoulder internal rotation and elbow extension angular velocities; forward and lateral trunk tilt; and ball speed. A one-way analysis of variance (P < 0.01) was used to assess kinematic differences. Shoulder horizontal adduction and shoulder external rotation at lead foot contact and ball speed at the instant of ball release were significantly different among countries. The greater shoulder horizontal abduction observed in Cuban pitchers at lead foot contact is thought to be an important factor in the generation of force throughout the arm cocking and arm acceleration phases, and may in part explain why Cuban pitchers generated the greatest ball release speed. We conclude that pitching kinematics are similar among baseball pitchers from different countries.
Assuntos
Beisebol/fisiologia , Movimento/fisiologia , Ombro/fisiologia , Aceleração , Adulto , Austrália , Fenômenos Biomecânicos , Comparação Transcultural , Cuba , Cotovelo/fisiologia , Humanos , Itália , Japão , Coreia (Geográfico) , Contração Muscular/fisiologia , Músculo Esquelético/fisiologia , Países Baixos , Nicarágua , Amplitude de Movimento Articular/fisiologia , Rotação , Análise e Desempenho de Tarefas , Estados Unidos , Gravação em VídeoRESUMO
PURPOSE: Improper lifting techniques may increase injury risks and decrease performance. The aim of this study was to compare and contrast biomechanical parameters between sumo and conventional style deadlifts and between high- and low-skilled lifters who participated in the powerlifting event during the 1999 Special Olympics World Games. METHODS: Two synchronized video cameras collected 60 Hz of data from 40 subjects. Parameters were quantified at barbell liftoff (LO), when the barbell passed the knees (KP), and at lift completion. RESULTS: Compared with the conventional group, the sumo group had a 100% greater stance width, 20% smaller hand width, 10% less vertical bar distance, a more vertical trunk at LO, a more horizontal thigh at LO and KP, a less vertical shank at KP, and greater forefoot abduction. The sumo group generated ankle dorsiflexor, knee extensor, and hip extensor moments, whereas the conventional group produced ankle plantar flexor, knee flexor and extensor, and hip extensor moments. Compared with low-skilled lifters, high-skilled lifters had a 40% greater barbell load, 15% greater stance width (sumo group only), greater knee flexion at LO (conventional group only), greater knee extension at KP, a less vertical shank position at LO (sumo group only), 15% less vertical bar distance, less first peak bar velocity between LO and KP (conventional group only), smaller plantar flexor and hip extensor moment arms at LO and KP, and greater knee extensor moment arms at LO. CONCLUSIONS: The sumo deadlift may be more effective in working ankle dorsiflexors and knee extensors, whereas the conventional deadlift may be more effective in working ankle plantar flexors and knee flexors. High-skilled lifters exhibited better lifting mechanics than low-skilled lifters by keeping the bar closer to the body, which may both enhance performance and minimize injury risk.
Assuntos
Traumatismos em Atletas/etiologia , Levantamento de Peso/fisiologia , Adulto , Tornozelo/fisiologia , Fenômenos Biomecânicos , Humanos , Joelho/fisiologia , Masculino , Fatores de Risco , Gravação em VídeoRESUMO
PURPOSE: The purpose of this study was to quantify biomechanical parameters employing two-dimensional (2-D) and three-dimensional (3-D) analyses while performing the squat with varying stance widths. METHODS: Two 60-Hz cameras recorded 39 lifters during a national powerlifting championship. Stance width was normalized by shoulder width (SW), and three stance groups were defined: 1) narrow stance squat (NS), 107 +/- 10% SW; 2) medium stance squat (MS), 142 +/- 12% SW; and 3) wide stance squat (WS), 169 +/- 12% SW. RESULTS: Most biomechanical differences among the three stance groups and between 2-D and 3-D analyses occurred between the NS and WS. Compared with the NS at 45 degrees and 90 degrees knee flexion angle (KF), the hips flexed 6-11 degrees more and the thighs were 7-12 degrees more horizontal during the MS and WS. Compared with the NS at 90 degrees and maximum KF, the shanks were 5-9 degrees more vertical and the feet were turned out 6 degrees more during the WS. No significant differences occurred in trunk positions. Hip and thigh angles were 3-13 degrees less in 2-D compared with 3-D analyses. Ankle plantar flexor (10-51 N.m), knee extensor (359-573 N.m), and hip extensor (275-577 N.m) net muscle moments were generated for the NS, whereas ankle dorsiflexor (34-284 N.m), knee extensor (447-756 N.m), and hip extensor (382-628 N.m) net muscle moments were generated for the MS and WS. Significant differences in ankle and knee moment arms between 2-D and 3-D analyses were 7-9 cm during the NS, 12-14 cm during the MS, and 16-18 cm during the WS. CONCLUSIONS: Ankle plantar flexor net muscle moments were generated during the NS, ankle dorsiflexor net muscle moments were produced during the MS and WS, and knee and hip moments were greater during the WS compared with the NS. A 3-D biomechanical analysis of the squat is more accurate than a 2-D biomechanical analysis, especially during the WS.
Assuntos
Contração Muscular/fisiologia , Músculo Esquelético/fisiologia , Postura , Levantamento de Peso/fisiologia , Adulto , Fenômenos Biomecânicos , Humanos , Articulações/fisiologia , Cinética , Masculino , Pessoa de Meia-IdadeRESUMO
PURPOSE: Because a strong and stable knee is paramount to an athlete's or patient's success, an understanding of knee biomechanics while performing the squat is helpful to therapists, trainers, sports medicine physicians, researchers, coaches, and athletes who are interested in closed kinetic chain exercises, knee rehabilitation, and training for sport. The purpose of this review was to examine knee biomechanics during the dynamic squat exercise. METHODS: Tibiofemoral shear and compressive forces, patellofemoral compressive force, knee muscle activity, and knee stability were reviewed and discussed relative to athletic performance, injury potential, and rehabilitation. RESULTS: Low to moderate posterior shear forces, restrained primarily by the posterior cruciate ligament (PCL), were generated throughout the squat for all knee flexion angles. Low anterior shear forces, restrained primarily by the anterior cruciate ligament (ACL), were generated between 0 and 60 degrees knee flexion. Patellofemoral compressive forces and tibiofemoral compressive and shear forces progressively increased as the knees flexed and decreased as the knees extended, reaching peak values near maximum knee flexion. Hence, training the squat in the functional range between 0 and 50 degrees knee flexion may be appropriate for many knee rehabilitation patients, because knee forces were minimum in the functional range. Quadriceps, hamstrings, and gastrocnemius activity generally increased as knee flexion increased, which supports athletes with healthy knees performing the parallel squat (thighs parallel to ground at maximum knee flexion) between 0 and 100 degrees knee flexion. Furthermore, it was demonstrated that the parallel squat was not injurious to the healthy knee. CONCLUSIONS: The squat was shown to be an effective exercise to employ during cruciate ligament or patellofemoral rehabilitation. For athletes with healthy knees, performing the parallel squat is recommended over the deep squat, because injury potential to the menisci and cruciate and collateral ligaments may increase with the deep squat. The squat does not compromise knee stability, and can enhance stability if performed correctly. Finally, the squat can be effective in developing hip, knee, and ankle musculature, because moderate to high quadriceps, hamstrings, and gastrocnemius activity were produced during the squat.
Assuntos
Fenômenos Biomecânicos , Articulação do Joelho/fisiologia , Levantamento de Peso/fisiologia , Adulto , Humanos , Estados UnidosRESUMO
PURPOSE: Strength athletes often employ the deadlift in their training or rehabilitation regimens. The purpose of this study was to quantify kinematic and kinetic parameters by employing a three-dimensional analysis during sumo and conventional style deadlifts. METHODS: Two 60-Hz video cameras recorded 12 sumo and 12 conventional style lifters during a national powerlifting championship. Parameters were quantified at barbell liftoff (LO), at the instant the barbell passed the knees (KP), and at lift completion. Unpaired t-tests (P < 0.05) were used to compare all parameters. RESULTS: At LO and KP, thigh position was 11-16 degrees more horizontal for the sumo group, whereas the knees and hips extended approximately 12 degrees more for the conventional group. The sumo group had 5-10 degrees greater vertical trunk and thigh positions, employed a wider stance (70 +/- 11 cm vs 32 +/- 8 cm), turned their feet out more (42 +/- 8 vs 14 +/- 6 degrees). and gripped the bar with their hands closer together (47 +/- 4 cm vs 55 +/- 10 cm). Vertical bar distance, mechanical work, and predicted energy expenditure were approximately 25-40% greater in the conventional group. Hip extensor, knee extensor, and ankle dorsiflexor moments were generated for the sumo group, whereas hip extensor, knee extensor, knee flexor, and ankle plantar flexor moments were generated for the conventional group. Ankle and knee moments and moment arms were significantly different between the sumo and conventional groups, whereas hip moments and moments arms did not show any significantly differences. Three-dimensional calculations were more accurate and significantly different than two-dimensional calculations, especially for the sumo deadlift. CONCLUSIONS: Biomechanical differences between sumo and conventional deadlifts result from technique variations between these exercises. Understanding these differences will aid the strength coach or rehabilitation specialist in determining which deadlift style an athlete or patient should employ.
Assuntos
Articulações/fisiologia , Levantamento de Peso/fisiologia , Adulto , Fenômenos Biomecânicos , Humanos , Cinética , Masculino , Postura , Suporte de CargaRESUMO
The purpose of this review is to determine how throwing overweight and underweight baseballs affects baseball throwing velocity and accuracy. Two studies examined how a warm-up with overweight baseballs affected throwing velocity and accuracy of 5 oz regulation baseballs. One of these studies showed significant increases in throwing velocity and accuracy, while the other study found no significant differences. Three training studies (6 to 12 weeks in duration) using overweight baseballs were conducted to determine how they affected ball accuracy while throwing regulation baseballs. No significant differences were found in any study. From these data it is concluded that warming up or training with overweight baseballs does not improve ball accuracy. Seven overweight and 4 underweight training studies (6 to 12 weeks in duration) were conducted to determine how throwing velocity of regulation baseballs was affected due to training with these overweight and underweight baseballs. The overweight baseballs ranged in weight from 5.25 to 17 oz, while the underweight baseballs were between 4 and 4.75 oz. Data from these training studies strongly support the practice of training with overweight and underweight baseballs to increase throwing velocity of regulation baseballs. Since no injuries were reported throughout the training studies, throwing overweight and underweight baseballs may not be more stressful to the throwing arm compared to throwing regulation baseballs. However, since currently there are no injury data related to throwing overweight and underweight baseballs, this should be the focus of subsequent studies. In addition, research should be initiated to determine whether throwing kinematics and kinetics are different between throwing regulation baseballs and throwing overweight and underweight baseballs.
Assuntos
Braço/fisiologia , Beisebol/lesões , Beisebol/fisiologia , Terapia por Exercício/métodos , Animais , Fenômenos Biomecânicos , Humanos , Amplitude de Movimento Articular , Ratos , Torque , Ferimentos e Lesões/etiologia , Ferimentos e Lesões/prevenção & controleRESUMO
Proper biomechanics help baseball pitchers minimize their risk of injury and maximize performance. However previous studies involved adult pitchers only. In this study, 23 youth, 33 high school, 115 college, and 60 professional baseball pitchers were analyzed. Sixteen kinematic (11 position and five velocity), eight kinetic, and six temporal parameters were calculated and compared among the four levels of competition. Only one of the 11 kinematic position parameters showed significant differences among the four levels, while all five velocity parameters showed significant differences. All eight kinetic parameters increased significantly with competition level. None of the six temporal parameters showed significant differences. Since 16 of the 17 position and temporal parameters showed no significant differences, this study supports the philosophy that a child should be taught 'proper' pitching mechanics for use throughout a career. Kinetic differences observed suggest greater injury risk at higher competition levels. Since adult pitchers did not demonstrate different position or temporal patterns than younger pitchers, increases in joint forces and torques were most likely due to increased strength and muscle mass in the higher level athlete. The greater shoulder and elbow angular velocities produced by high-level pitchers were most likely due to the greater torques they generated during the arm cocking and acceleration phases. The combination of more arm angular velocity and a longer arm resulted in greater linear ball velocity for the higher level pitcher. Thus, it appears that the natural progression for successful pitching is to learn proper mechanics as early as possible, and build strength as the body matures.
Assuntos
Beisebol/fisiologia , Adolescente , Adulto , Braço/fisiologia , Traumatismos em Atletas/prevenção & controle , Fenômenos Biomecânicos , Criança , Articulação do Cotovelo/fisiologia , Humanos , Masculino , Educação Física e Treinamento , Aptidão Física , Rotação , Articulação do Ombro/fisiologiaRESUMO
An analytical model of the knee joint was developed to estimate the forces at the knee during exercise. Muscle forces were estimated based upon electromyographic activities during exercise and during maximum voluntary isometric contraction (MVIC), physiological cross-sectional area (PCSA), muscle fiber length at contraction and the maximum force produced by an unit PCSA under MVIC. Tibiofemoral compressive force and cruciate ligaments' tension were determined by using resultant force and torque at the knee, muscle forces, and orientations and moment arms of the muscles and ligaments. An optimization program was used to minimize the errors caused by the estimation of the muscle forces. The model was used in a ten-subject study of open kinetic chain exercise (seated knee extension) and closed kinetic chain exercises (leg press and squat). Results calculated with this model were compared to those from a previous study which did not consider muscle length and optimization. Peak tibiofemoral compressive forces were 3134 +/- 1040 N during squat, 3155 +/- 755 N during leg press and 3285 +/- 1927 N during knee extension. Peak posterior cruciate ligament tensions were 1868 +/- 878 N during squat, 1866 +/- 383 N during leg press and 959 +/- 300 N for seated knee extension. No significant anterior cruciate ligament (ACL) tension was found during leg press and squat. Peak ACL tension was 142 +/- 257 N during seated knee extension. It is demonstrated that the current model provided better estimation of knee forces during exercises, by preventing significant overestimates of tibiofemoral compressive forces and cruciate ligament tensions.
Assuntos
Exercício Físico , Articulação do Joelho/fisiologia , Modelos Biológicos , Ligamento Cruzado Anterior/fisiologia , Fenômenos Biomecânicos , Eletromiografia , Humanos , Contração Muscular/fisiologia , Músculo Esquelético/fisiologia , Ligamento Cruzado Posterior/fisiologia , TorqueRESUMO
Underhand pitching has received minimal attention in the sports medicine literature. This may be due to the perception that, compared with overhead pitching, the underhand motion creates less stress on the arm, which results in fewer injuries. The purpose of this study was to calculate kinematic and kinetic parameters for the pitching motion used in fast pitch softball. Eight female fast pitch softball pitchers were recorded with a four-camera system (200 Hz). The results indicated that high forces and torques were experienced at the shoulder and elbow during the delivery phase. Peak compressive forces at the elbow and shoulder equal to 70-98% of body weight were produced. Shoulder extension and abduction torques equal to 9-10% of body weight x height were calculated. Elbow flexion torque was exerted to control elbow extension and initiate elbow flexion. The demand on the biceps labrum complex to simultaneously resist glenohumeral distraction and produce elbow flexion makes this structure susceptible to overuse injury.
Assuntos
Beisebol/fisiologia , Cotovelo/fisiologia , Amplitude de Movimento Articular/fisiologia , Ombro/fisiologia , Adulto , Traumatismos em Atletas/etiologia , Traumatismos em Atletas/fisiopatologia , Traumatismos em Atletas/prevenção & controle , Beisebol/lesões , Fenômenos Biomecânicos , Feminino , Humanos , Valores de Referência , Medição de Risco , Sensibilidade e Especificidade , Lesões do Ombro , Lesões no CotoveloRESUMO
PURPOSE: Although closed (CKCE) and open (OKCE) kinetic chain exercises are used in athletic training and clinical environments, few studies have compared knee joint biomechanics while these exercises are performed dynamically. The purpose of this study was to quantify knee forces and muscle activity in CKCE (squat and leg press) and OKCE (knee extension). METHODS: Ten male subjects performed three repetitions of each exercise at their 12-repetition maximum. Kinematic, kinetic, and electromyographic data were calculated using video cameras (60 Hz), force transducers (960 Hz), and EMG (960 Hz). Mathematical muscle modeling and optimization techniques were employed to estimate internal muscle forces. RESULTS: Overall, the squat generated approximately twice as much hamstring activity as the leg press and knee extensions. Quadriceps muscle activity was greatest in CKCE when the knee was near full flexion and in OKCE when the knee was near full extension. OKCE produced more rectus femoris activity while CKCE produced more vasti muscle activity. Tibiofemoral compressive force was greatest in CKCE near full flexion and in OKCE near full extension. Peak tension in the posterior cruciate ligament was approximately twice as great in CKCE, and increased with knee flexion. Tension in the anterior cruciate ligament was present only in OKCE, and occurred near full extension. Patellofemoral compressive force was greatest in CKCE near full flexion and in the mid-range of the knee extending phase in OKCE. CONCLUSION: An understanding of these results can help in choosing appropriate exercises for rehabilitation and training.
Assuntos
Exercício Físico/fisiologia , Articulação do Joelho/fisiologia , Levantamento de Peso/fisiologia , Adulto , Fenômenos Biomecânicos , Terapia por Exercício , Humanos , Cinética , Masculino , Movimento , Músculo Esquelético/fisiologiaRESUMO
We chose to investigate tibiofemoral joint kinetics (compressive force, anteroposterior shear force, and extension torque) and electromyographic activity of the quadriceps, hamstring, and gastrocnemius muscles during open kinetic chain knee extension and closed kinetic chain leg press and squat. Ten uninjured male subjects performed 4 isotonic repetitions with a 12 repetition maximal weight for each exercise. Tibiofemoral forces were calculated using electromyographic, kinematic, and kinetic data. During the squat, the maximal compressive force was 6139 +/- 1708 N, occurring at 91 degrees of knee flexion; whereas the maximal compressive force for the knee extension exercise was 4598 +/- 2546 N (at 90 degrees knee flexion). During the closed kinetic chain exercises, a posterior shear force (posterior cruciate ligament stress) occurred throughout the range of motion, with the peak occurring from 85 degrees to 105 degrees of knee flexion. An anterior shear force (anterior cruciate ligament stress) was noted during open kinetic chain knee extension from 40 degrees to full extension; a peak force of 248 +/- 259 N was noted at 14 degrees of knee flexion. Electromyographic data indicated greater hamstring and quadriceps muscle co-contraction during the squat compared with the other two exercises. During the leg press, the quadriceps muscle electromyographic activity was approximately 39% to 52% of maximal velocity isometric contraction; whereas hamstring muscle activity was minimal (12% maximal velocity isometric contraction). This study demonstrated significant differences in tibiofemoral forces and muscle activity between the two closed kinetic chain exercises, and between the open and closed kinetic chain exercises.
Assuntos
Exercício Físico/fisiologia , Articulação do Joelho/fisiologia , Músculo Esquelético/fisiologia , Adulto , Fenômenos Biomecânicos , Eletromiografia , Humanos , Perna (Membro)/fisiologia , Masculino , Contração Muscular/fisiologiaRESUMO
Proper throwing mechanics may enable an athlete to achieve maximum performance with minimum chance of injury. While quantifiable differences do exist in proper mechanics for various sports, certain similarities are found in all overhand throws. One essential property is the utilisation of a kinetic chain to generate and transfer energy from the larger body parts to the smaller, more injury-prone upper extremity. This kinetic chain in throwing includes the following sequence of motions: stride, pelvis rotation, upper torso rotation, elbow extension, shoulder internal rotation and wrist flexion. As each joint rotates forward, the subsequent joint completes its rotation back into a cocked position, allowing the connecting segments and musculature to be stretched and eccentrically loaded. Most notable is the external rotation of the shoulder, which reaches a maximum value of approximately 180 degrees. This biomechanical measurement is a combination of true glenohumeral rotation, trunk hyperextension and scapulothoracic motion. Near the time of maximum shoulder external rotation (ERmax), shoulder and elbow musculature eccentrically contract to produce shoulder internal rotation torque and elbow varus torque. Both the shoulder and the elbow are susceptible to injury at this position. At ball release, significant energy and momentum have been transferred to the ball and throwing arm. After ball release, a kinetic chain is used to decelerate the rapidly moving arm with the entire body. Shoulder and elbow muscles produce large compressive forces to resist joint distraction. Both joints are susceptible to injury during arm deceleration.
Assuntos
Traumatismos em Atletas/fisiopatologia , Esportes/fisiologia , Braço/fisiologia , Traumatismos em Atletas/etiologia , Traumatismos em Atletas/prevenção & controle , Fenômenos Biomecânicos , Articulação do Cotovelo/fisiologia , Transferência de Energia , Feminino , Humanos , Cinética , Perna (Membro)/fisiologia , Masculino , Músculo Esquelético/fisiologia , Pelve/fisiologia , Rotação , Lesões do Ombro , Articulação do Ombro/fisiologia , Tórax/fisiologia , Torque , Articulação do Punho/fisiologia , Lesões no CotoveloRESUMO
Elbow and shoulder kinetics for 26 highly skilled, healthy adult pitchers were calculated using high-speed motion analysis. Two critical instants were 1) shortly before the arm reached maximum external rotation, when 67 N-m of shoulder internal rotation torque and 64 N-m of elbow varus torque were generated, and 2) shortly after ball release, when 1090 N of shoulder compressive force was produced. Inability to generate sufficient elbow varus torque may result in medial tension, lateral compression, or posteromedial impingement injury. At the glenohumeral joint, compressive force, joint laxity, and 380 N of anterior force during arm cocking can lead to anterior glenoid labral tear. Rapid internal rotation in combination with these forces can produce a grinding injury factor on the labrum. After ball release, 400 N of posterior force, 1090 N of compressive force, and 97 N-m of horizontal abduction torque are generated at the shoulder; contribution of rotator cuff muscles in generating these loads may result in cuff tensile failure. Horizontal adduction, internal rotation, and superior translation of the abducted humerus may cause subacromial impingement. Tension in the biceps tendon, due to muscle contraction for both elbow flexion torque and shoulder compressive force, may tear the anterosuperior labrum.
Assuntos
Beisebol/lesões , Beisebol/fisiologia , Lesões no Cotovelo , Articulação do Cotovelo/fisiologia , Lesões do Ombro , Articulação do Ombro/fisiologia , Aceleração , Acrômio/lesões , Acrômio/fisiologia , Adulto , Desaceleração , Humanos , Úmero/lesões , Úmero/fisiologia , Instabilidade Articular/fisiopatologia , Masculino , Filmes Cinematográficos , Contração Muscular , Músculo Esquelético/lesões , Músculo Esquelético/fisiologia , Amplitude de Movimento Articular , Rotação , Manguito Rotador/fisiologia , Lesões do Manguito Rotador , Estresse Mecânico , Traumatismos dos Tendões/fisiopatologia , Tendões/fisiologia , Resistência à TraçãoAssuntos
Disfunções Sexuais Fisiológicas/terapia , Doenças das Glândulas Suprarrenais/terapia , Doenças do Sistema Endócrino/terapia , Eunuquismo/terapia , Feminino , Humanos , Hipotálamo/fisiopatologia , Masculino , Menopausa , Doenças Ovarianas/terapia , Pancreatopatias/terapia , Doenças das Paratireoides/terapia , Doenças da Hipófise/terapia , Síndrome do Ovário Policístico/terapia , Disfunções Sexuais Fisiológicas/fisiopatologia , Doenças Testiculares/terapia , Doenças da Glândula Tireoide/terapia , Síndrome de Turner/terapiaAssuntos
Nanismo Hipofisário/tratamento farmacológico , Hormônio do Crescimento/administração & dosagem , Adolescente , Adulto , Criança , Nanismo Hipofisário/etiologia , Fluoximesterona/uso terapêutico , Crescimento , Humanos , Masculino , Fraturas Cranianas/complicações , Tiroxina/uso terapêutico , Fatores de TempoAssuntos
Crescimento , Doenças da Hipófise/terapia , Criocirurgia/efeitos adversos , Diabetes Insípido/etiologia , Diabetes Mellitus/etiologia , Nanismo Hipofisário/tratamento farmacológico , Feminino , Gigantismo/radioterapia , Gigantismo/cirurgia , Gigantismo/terapia , Gonadotropinas Hipofisárias/uso terapêutico , Hormônio do Crescimento/antagonistas & inibidores , Hormônio do Crescimento/uso terapêutico , Humanos , Hipopituitarismo/complicações , Masculino , Meningite/etiologia , Doenças da Hipófise/complicações , Hipófise/cirurgia , Prognóstico , Radioterapia/efeitos adversosRESUMO
Two male patients with achondroplastic dwarfism aged 7-5/12 and 14(1/2) years were treated with human growth hormone 5 mg daily. Both showed nitrogen retention on balance studies, the older second patient to a marked degree. In the younger patient, height increased from 95.4 to 106.3 cm on hgh 5 mg daily alone for 14 out of 24 months. The rate of growth approximately doubled during the first two treatment periods as compared with the pre-treatment rate. In the second older patient hgh was administered 5 mg daily intramuscularly for 21 out of 33 months. Growth from 129.6 cm to 137.8 cm occurred with the rate increasing following the addition of Na-1-thyroxine to the routine. This increased growth rate occurred during the post-puberty deceleration phase. Bone ages, interpreted from changes in the phalanges and metacarpals, increased from 4(1/2) to 6 years during 16 months in Case 1, and from 13(1/2) to 18 years in 33 months in Case 2. Transient adolescent gynecomastia appeared in Case 2. No local or general toxic effects were noted. These results are suggestive, but whether or not the eventual height of an achondroplastic dwarf can be significantly altered must await further studies.