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Folia Microbiol (Praha) ; 63(4): 517-523, 2018 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-29488180

RESUMO

Candida bracarensis is an emerging cryptic species within the Candida glabrata clade. To date, little is known about its epidemiology, virulence, and antifungal susceptibility. This study documents the occurrence of C. bracarensis for the first time in Mexico and focuses on its in vitro production of hydrolytic enzymes, as well as antifungal susceptibility to echinocandins. This strain was isolated from a vaginal swab of a female with vulvovaginal candidosis; exhibited a very strong activity of aspartyl proteinase, phospholipase, and hemolysin; and was susceptible to caspofungin, anidulafungin, and micafungin (MIC = 0.031 µg/mL). Data obtained could contribute to the knowledge of the epidemiology and virulence attributes of this yeast as a fungal opportunistic human pathogen.


Assuntos
Antifúngicos/farmacologia , Candida/efeitos dos fármacos , Candida/enzimologia , Candidíase Vulvovaginal/microbiologia , Hidrolases/metabolismo , Viabilidade Microbiana/efeitos dos fármacos , Candida/classificação , Candida/fisiologia , DNA Fúngico/genética , DNA Espaçador Ribossômico/genética , Feminino , Genoma Fúngico , Humanos , México , Testes de Sensibilidade Microbiana
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