RESUMO
Type 2 diabetes mellitus is a serious public health concern because it produces considerable impact on human life and health expenditures. Overweight and obesity plays a major role in the pathogenesis of type 2 diabetes. Fasting blood sugar is the diagnostic marker for type 2 diabetes mellitus. Glycated hemoglobin is widely used as an index of mean glycemia. The aim of this study was to find out the effect of body mass index, fasting serum glucose, glycated hemoglobin in type 2 diabetic female patients in Mymensingh locality. This cross-sectional analytical type of study was carried out in the department of Physiology, Mymensingh Medical College (MMC), Mymensingh, Bangladesh from July 2022 to June 2023. A total 200 subjects age ranged between 30-59 years were selected and were grouped as control group, Group I (100, non-diabetic female) and study group, Group II (100, female diabetic patients). SPSS was used to calculate and analyzed the result. Anthropometric measurements such as height and weight taken in meter and kilogram respectively, laboratory analysis of fasting serum glucose was determined by GOD- POD method, glycated hemoglobin by fluorescence immunoassay method. Results were expressed as mean (± SD) and by unpaired Student's 't' test. The mean (± SD) of BMI of control group (non-diabetic female) and study group (female diabetic patients) were 22.01±1.50 and 26.86±2.00 kg/m² respectively. In study group BMI was increased in comparison to control group. The mean (± SD) of fasting serum glucose of control group (non-diabetic female) and study group (female diabetic patients) were 4.36±0.84 and 8.25±2.52 mmol/L respectively. In study group fasting serum glucose was increased in comparison to control group. The mean (± SD) of glycated hemoglobin of control group (non-diabetic female) and study group (female diabetic patients) were 5.07±0.47 and 7.45±1.34 % respectively. In study group glycated hemoglobin was increased in comparison to control group. In this study we found that body mass index, fasting serum glucose, glycated hemoglobin was significant in study group (female type 2 diabetic patients) in comparison to control group (healthy female adults of same age group). Therefore, by this study we recommended that for prevention of complications related to type 2 diabetes mellitus routine estimation of these parameters is important.