Prevalence of Dyslipidemia among School-Age Children and Adolescents in Addis Ababa, Ethiopia.

Objective Lipid abnormalities during childhood might be associated with a higher risk of atherosclerosis development in adulthood. In Ethiopia, there were no data on this area. The present work was aimed at assessing the lipid profile abnormalities among children and adolescents aged between 5 and 17 years, in Addis Ababa, Ethiopia. Materials and Methods The present school-based cross-sectional study was done from March 2019 to October 2019 in the capital city, Addis Ababa. A total of 504 students were randomly recruited for this study. The total cholesterol, triglyceride, low-density lipoprotein, and high-density lipoprotein-cholesterol levels were determined using the Cobas c501 automated chemistry analyzer. The prevalence of lipid abnormalities was described in percentages. Bivariate and multivariate analyses were performed, and data with p -value less than 0.05 was considered statistically significant. Results Dyslipidemia in at least one of the lipid profiles was observed in 322 (63.9%) school children, whereas only one of the participants had an abnormality in all four lipid profile tests. The prevalence of total cholesterol 200 mg/dL or higher, low-density lipoprotein 130 mg/dL or higher, high-density lipoprotein less than 40 mg/dL, and triglycerides 130 mg/dL or higher was in 14 (2.8%), 16 (3.2%), 294 (58.4%), and 46 (19.1%) participants, respectively. Conclusion In the current work, the majority of the study participants had a normal lipid profile except increased prevalence of a reduced concentration of high-density lipoprotein-cholesterol. The overall prevalence of serum lipid abnormalities was 63.9%. Serum lipid levels did not show significant differences with sex, age, fasting habits, or obesity.

Land Use and Land Cover Dynamics and Properties of Soils under Different Land Uses in the Tejibara Watershed, Ethiopia.

Land use changes have long been considered among many factors responsible for physical and chemical soil degradation. This study was conducted to evaluate land use and land cover (LULC) changes and their cumulative effects over 30 years (from 1989 to 2019) on the current physical and chemical properties of soils in the Tejibara watershed, Ethiopia. Image analysis and LULC classifications were performed using ERDAS IMAGINE 2014 and ArcGIS 10.4 software, respectively. For the determination of soil properties, four land use types (natural forest, eucalyptus plantation, cultivated, and grazing lands) and two soil depths (0-20 and 20-40 cm) were used. Triplicate composite soil samples were collected from each land use type and soil depths. For the determination of physical (texture and bulk density) and chemical soil properties such as electrical conductivity (EC), organic matter (OM), total nitrogen (TN), and available phosphorus (AP), standard laboratory procedures were employed. The image analysis results for all of the years studied show that cultivated lands have increased in area at the expense of forest and grazing lands. Silt content, clay content, AP, and pH were significantly affected by land use as the main effect while the interaction effects of soil depth and land use were significant for total N and OM only. The highest (10.1 mg/kg) and the lowest (4.9 mg/kg) AP contents were observed in the forest and the grazing lands, respectively. Soil total N content was highest in the forest lands (0.32%) and lowest in cultivated lands (0.06%). Concerning OM content, the highest (11.0%) and the lowest (0.8%) values were recorded in the forest and cultivated lands, respectively. Generally, this study showed that land use changes have reduced the areal coverage by forest and grazing lands and have negatively affected the soil properties. This implies that land use change without soil fertility measures that are appropriate to the area could cause enhanced land degradation and thereby reduce the productivity of the study area soils.

To End TB, First-Ever High-Level Meeting on Tuberculosis Must Address Stigma.

World leaders gather to consolidate their commitment to ending tuberculosis (TB). Vital to the success of renewed efforts is an overdue recognition of the pervasive and pernicious influence of TB stigma. TB stigma is sustained in structures, policies, traditions, and norms. Innovative modifications to infection control, drug dispensing, and surveillance practices are required to increase demand for TB screening and effective therapeutic alliances among those diagnosed. The authors argue that reducing TB stigma requires a scientific and inclusive process, with prominent roles for TB survivors and a willingness to integrate and learn from other stigmatized conditions.