[Isoniazid-induced visual hallucinosis]. / Hallucinose visuelle induite par l'isoniazide.

INTRODUCTION: Isoniazid is the antituberculosis drug that causes psychiatric manifestations most often. Their incidence is nonetheless rare: a review of the literature found only 16 cases. Only one author has reported hallucinosis, defined by isolated sensorial symptoms, and perceptions not believed to be the reality of the object. CASE: We report a case of a 42-year-old woman, a nonsmoker with no particular history and with lymph node tuberculosis. Three weeks after beginning antituberculosis treatment (isoniazid, rifampicin, pyrazinamide and streptomycin), visual hallucinosis and a headache appeared. The symptoms disappeared when Isoniazid was stopped and an anxiolytic drug prescribed. These findings suggest that these effects were due to isoniazid. DISCUSSION: Two mechanisms may explain these psychiatric manifestations: vitamin B6 deficiency or interference between isoniazid and bioamine metabolism.

[Pulmonary artery aneurysms in Behçet's disease: contribution of imaging in 5 cases]. / Anévrysmes des artères pulmonaires au cours de la maladie de Behçet.

Pulmonary involvement in Behçet's disease is an uncommon condition (12%). Thromboembolism of the superior vena cava and/or other mediastinal veins, aneurysms of the aorta and pulmonary arteries are the main vascular manifestations in addition to pulmonary infarct and intrathoracic hemorrhage. Despite their scarcity, respiratory symptoms may be life-threatening. The aim of this study was to assess the contribution of thoracic imaging for one of the most serious aspects of the disease: pulmonary artery aneurysm. We report five patients with pulmonary artery aneurysms (mean age: 39.5 years). Hemoptysia revealed Behçet's disease in three. Initially explored by conventional radiography, computed tomography and angiography, pulmonary artery aneurysms are currently investigated well with helicoidal computed tomography, digital angiography, magnetic resonance imaging (MRI) and angio-MRI. These imaging techniques provide helpful information for the diagnosis of Behçet's disease.