Judging robot ability: How people form implicit and explicit impressions of robot competence.

Robots' proliferation throughout society offers many opportunities and conveniences. However, our ability to effectively employ these machines relies heavily on our perceptions of their competence. In six studies (N = 2,660), participants played a competitive game with a robot to learn about its capabilities. After the learning experience, we measured explicit and implicit competence impressions to investigate how they reflected the learning experience. We observed two distinct dissociations between people's implicit and explicit competence impressions. Firstly, explicit impressions were uniquely sensitive to oddball behaviors. Implicit impressions only incorporated unexpected behaviors when they were moderately prevalent. Secondly, after forming a strong initial impression, explicit, but not implicit, impression updating demonstrated a positivity bias (i.e., an overvaluation of competence information). These findings suggest that the same learning experience with a robot is expressed differently at the implicit versus explicit level. We discuss implications from a social cognitive perspective, and how this work may inform emerging work on psychology toward robots. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Testing the automaticity features of the affect misattribution procedure: The roles of awareness and intentionality.

The affect misattribution procedure (AMP) is a measure of implicit evaluations, designed to index the automatic retrieval of evaluative knowledge. The AMP effect consists in participants evaluating neutral target stimuli positively when preceded by positive primes and negatively when preceded by negative primes. After multiple prior tests of intentionality, Hughes et al. (Behav Res Methods 55(4):1558-1586, 2023) examined the role of awareness in the AMP and found that AMP effects were larger when participants indicated that their response was influenced by the prime than when they did not. Here we report seven experiments (six preregistered; N = 2350) in which we vary the methodological features of the AMP to better understand this awareness effect. In Experiments 1-4, we establish variability in the magnitude of the awareness effect in response to variations in the AMP procedure. By introducing further modifications to the AMP procedure, Experiments 5-7 suggest an alternative explanation of the awareness effect, namely that awareness can be the outcome, rather than the cause, of evaluative congruency between primes and responses: Awareness effects emerged even when awareness could not have contributed to AMP effects, including when participants judged influence awareness for third parties or primes were presented post hoc. Finally, increasing the evaluative strength of the primes increased participants' tendency to misattribute AMP effects to the influence of target stimuli. Together, the present findings suggest that AMP effects can create awareness effects rather than vice versa and support the AMP's construct validity as a measure of unintentional evaluations of which participants are also potentially unaware.

Oppressed Groups Engender Implicit Positivity: Seven Demonstrations Using Novel and Familiar Targets.

Across seven preregistered studies in online adult volunteer samples (N = 5,323), we measured implicit evaluations of social groups following exposure to historical narratives about their oppression. Although the valence of such information is highly negative and its interpretation was left up to participants, implicit evaluations of oppressed groups shifted toward positivity, including in designs involving fictitious, well-known, and even self-relevant targets. The sole deviation from this pattern was observed in an experiment using a vignette about slavery in the United States, in response to which neither White nor Black Americans exhibited any change in implicit race attitudes. In line with propositional perspectives, these findings suggest that implicit evaluations (including, notably, implicit evaluations of well-known and self-relevant social groups) tend to change toward positivity in response to extremely negative information involving past oppression. However, macro-level phenomena, such as public awareness of histories of oppression, can modulate such updating processes.

Adjuvanted Fusion Protein Vaccine Induces Durable Immunity to Onchocerca volvulus in Mice and Non-Human Primates.

Onchocerciasis remains a debilitating neglected tropical disease. Due to the many challenges of current control methods, an effective vaccine against the causative agent Onchocerca volvulus is urgently needed. Mice and cynomolgus macaque non-human primates (NHPs) were immunized with a vaccine consisting of a fusion of two O. volvulus protein antigens, Ov-103 and Ov-RAL-2 (Ov-FUS-1), and three different adjuvants: Advax-CpG, alum, and AlT4. All vaccine formulations induced high antigen-specific IgG titers in both mice and NHPs. Challenging mice with O. volvulus L3 contained within subcutaneous diffusion chambers demonstrated that Ov-FUS-1/Advax-CpG-immunized animals developed protective immunity, durable for at least 11 weeks. Passive transfer of sera, collected at several time points, from both mice and NHPs immunized with Ov-FUS-1/Advax-CpG transferred protection to naïve mice. These results demonstrate that Ov-FUS-1 with the adjuvant Advax-CpG induces durable protective immunity against O. volvulus in mice and NHPs that is mediated by vaccine-induced humoral factors.

Evaluation of Dental Root Development Regarding Maxillary Canine Eruption Status after Secondary Alveolar Bone Grafting in Patients with Cleft Lip and Palate.

In children born with cleft lip and palate, the timing of the secondary alveolar bone graft (SABG) is crucial to its success; this involves estimating the eruption of the permanent maxillary canine. Altered dental eruption in this patient group gives impetus to the identification of dental developmental factors concerning maxillary canine eruption, which may steer the clinical decision of SABG timing. Records of over nine hundred patients who received SABG with pre- and post-operative cone beam computed tomography (CBCT) scans were analyzed for inclusion and divided into two groups (erupting or non-erupting canine after SABG). Roots of the maxillary canines and premolars were segmented from the cementoenamel junction then linear and volumetric measurements were performed. The pre- and post-operative root length and volume differences were calculated and compared statistically using independent sample tests and paired t-tests. No statistically significant differences were found in the volume change (%), or reciprocal of mean root length in the erupted and unerupted groups in the canine, first premolar, or second premolar roots except for an association between the post-operative dental root length of the canine and the maxillary canine eruption status. Therefore, assessment of root development from pre-treatment CBCT scans was not deemed worthy from a diagnostic perspective.

Trait attribution explains human-robot interactions.

Clark and Fischer (C&F) claim that trait attribution has major limitations in explaining human-robot interactions. We argue that the trait attribution approach can explain the three issues posited by C&F. We also argue that the trait attribution approach is parsimonious, as it assumes that the same mechanisms of social cognition apply to human-robot interaction.

Did Donald Trump's presidency reshape Americans' prejudices?

Did the presidency of Donald Trump affect Americans' intergroup attitudes? Converging evidence from recent experimental and longitudinal studies suggests that Trump's political rise led his supporters to increase their reported prejudice toward traditionally minoritized racial and religious groups in the USA.

Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques.

To prepare for future coronavirus (CoV) pandemics, it is desirable to generate vaccines capable of eliciting broadly neutralizing antibody responses to CoVs. Here, we show that immunization of macaques with SARS-CoV-2 spike (S) protein with a two-shot protocol generated potent serum receptor binding domain cross-neutralizing antibody responses to both SARS-CoV-2 and SARS-CoV-1. Furthermore, responses were equally effective against most SARS-CoV-2 variants of concern (VOCs) and some were highly effective against Omicron. This result contrasts with human infection or many two-shot vaccination protocols where responses were typically more SARS-CoV-2 specific and where VOCs were less well neutralized. Structural studies showed that cloned macaque neutralizing antibodies, particularly using a given heavy chain germline gene, recognized a relatively conserved region proximal to the angiotensin converting enzyme 2 receptor binding site (RBS), whereas many frequently elicited human neutralizing antibodies targeted more variable epitopes overlapping the RBS. B cell repertoire differences between humans and macaques appeared to influence the vaccine response. The macaque neutralizing antibodies identified a pan-SARS-related virus epitope region less well targeted by human antibodies that could be exploited in rational vaccine design.

Changes in Americans' prejudices during the presidency of Donald Trump.

The presidency of Donald Trump represented a relatively unique event in modern American history, whereby a sitting US president made numerous controversial remarks about minoritized groups yet nonetheless maintained substantial public support. Trump's comments constituted a departure from the egalitarian norms that had long characterized American political discourse. Here, we examine the potential effects of Trump's rhetoric on Americans' attitudes, predicting that these high-profile norm violations may have reshaped the personal prejudices of the American people. In 13 studies including over 10,000 participants, we tested how Americans' prejudice changed following the political ascension of Donald Trump. We found that explicit racial and religious prejudice significantly increased amongst Trump's supporters, whereas individuals opposed to Trump exhibited decreases in prejudice. Further, changing social norms appear to explain these changes in prejudice. These results suggest that Trump's presidency coincided with a substantial change in the topography of prejudice in the United States.

Long-acting capsid inhibitor protects macaques from repeat SHIV challenges.

Because no currently available vaccine can prevent HIV infection, pre-exposure prophylaxis (PrEP) with antiretrovirals (ARVs) is an important tool for combating the HIV pandemic1,2. Long-acting ARVs promise to build on the success of current PrEP strategies, which must be taken daily, by reducing the frequency of administration3. GS-CA1 is a small-molecule HIV capsid inhibitor with picomolar antiviral potency against a broad array of HIV strains, including variants resistant to existing ARVs, and has shown long-acting therapeutic potential in a mouse model of HIV infection4. Here we show that a single subcutaneous administration of GS-CA1 provides long-term protection against repeated rectal simian-human immunodeficiency virus (SHIV) challenges in rhesus macaques. Whereas all control animals became infected after 15 weekly challenges, a single 300 mg kg-1 dose of GS-CA1 provided per-exposure infection risk reduction of 97% for 24 weeks. Pharmacokinetic analysis showed a correlation between GS-CA1 plasma concentration and protection from SHIV challenges. GS-CA1 levels greater than twice the rhesus plasma protein-adjusted 95% effective concentration conferred 100% protection in this model. These proof-of-concept data support the development of capsid inhibitors as a novel long-acting PrEP strategy in humans.

Tetravalent Rabies-Vectored Filovirus and Lassa Fever Vaccine Induces Long-term Immunity in Nonhuman Primates.

BACKGROUND: The objective of this study is to evaluate the immunogenicity of adjuvanted monovalent rabies virus (RABV)-based vaccine candidates against Ebola virus (FILORAB1), Sudan virus (FILORAB2), Marburg virus (FILORAB3), Lassa virus (LASSARAB1), and combined trivalent vaccine candidate (FILORAB1-3) and tetravalent vaccine candidate (FILORAB1-3 and LASSARAB) in nonhuman primates. METHODS: Twenty-four Macaca fascicularis were randomly assigned into 6 groups of 4 animals. Each group was vaccinated with either a single adjuvanted vaccine, the trivalent vaccine, or the tetravalent vaccine at days 0 and 28. We followed the humoral immune responses for 1 year by antigen-specific enzyme-linked immunosorbent assays and RABV neutralization assays. RESULTS: High titers of filovirus and/or Lassa virus glycoprotein-specific immunoglobulin G were induced in the vaccinated animals. There were no significant differences between immune responses in animals vaccinated with single vaccines vs trivalent or tetravalent vaccines. In addition, all vaccine groups elicited strong rabies neutralizing antibody titers. The antigen-specific immune responses were detectable for 1 year in all groups. CONCLUSIONS: In summary, this study shows the longevity of the immune responses up to 365 days for a pentavalent vaccine-against Ebola virus, Sudan virus, Marburg virus, Lassa virus, and RABV-using a safe and effective vaccine platform.

The Long-Term Effects of New Evidence on Implicit Impressions of Other People.

Implicit impressions are often assumed to be difficult to update in light of new information. Even when an intervention appears to successfully change implicit evaluations, the effects have been found to be fleeting, reverting to baseline just hours or days later. Recent findings, however, show that two properties of new evidence-diagnosticity and believability-can result in very rapid implicit updating. In the current studies, we assessed the long-term effects of evidence possessing these two properties on implicit updating over periods of days, weeks, and months. Three studies assessed the malleability of implicit evaluations after memory consolidation (Study 1; N = 396) as well as the longer-term trajectories of implicit responses after exposure to new evidence about novel targets (Study 2; N = 375) and familiar ones (Study 3; N = 341). In contrast with recent work, our findings suggest that implicit impressions can exhibit both flexibility after consolidation and durability weeks or months later.

The Future of Women in Psychological Science.

There has been extensive discussion about gender gaps in representation and career advancement in the sciences. However, psychological science itself has yet to be the focus of discussion or systematic review, despite our field's investment in questions of equity, status, well-being, gender bias, and gender disparities. In the present article, we consider 10 topics relevant for women's career advancement in psychological science. We focus on issues that have been the subject of empirical study, discuss relevant evidence within and outside of psychological science, and draw on established psychological theory and social-science research to begin to chart a path forward. We hope that better understanding of these issues within the field will shed light on areas of existing gender gaps in the discipline and areas where positive change has happened, and spark conversation within our field about how to create lasting change to mitigate remaining gender differences in psychological science.

Incidental Attitude Formation via the Surveillance Task: A Preregistered Replication of the Olson and Fazio (2001) Study.

Evaluative conditioning is one of the most widely studied procedures for establishing and changing attitudes. The surveillance task is a highly cited evaluative-conditioning paradigm and one that is claimed to generate attitudes without awareness. The potential for evaluative-conditioning effects to occur without awareness continues to fuel conceptual, theoretical, and applied developments. Yet few published studies have used this task, and most are characterized by small samples and small effect sizes. We conducted a high-powered (N = 1,478 adult participants), preregistered close replication of the original surveillance-task study (Olson & Fazio, 2001). We obtained evidence for a small evaluative-conditioning effect when "aware" participants were excluded using the original criterion-therefore replicating the original effect. However, no such effect emerged when three other awareness criteria were used. We suggest that there is a need for caution when using evidence from the surveillance-task effect to make theoretical and practical claims about "unaware" evaluative-conditioning effects.

Using dynamic monitoring of choices to predict and understand risk preferences.

Navigating conflict is integral to decision-making, serving a central role both in the subjective experience of choice as well as contemporary theories of how we choose. However, the lack of a sensitive, accessible, and interpretable metric of conflict has led researchers to focus on choice itself rather than how individuals arrive at that choice. Using mouse-tracking-continuously sampling computer mouse location as participants decide-we demonstrate the theoretical and practical uses of dynamic assessments of choice from decision onset through conclusion. Specifically, we use mouse tracking to index conflict, quantified by the relative directness to the chosen option, in a domain for which conflict is integral: decisions involving risk. In deciding whether to accept risk, decision makers must integrate gains, losses, status quos, and outcome probabilities, a process that inevitably involves conflict. Across three preregistered studies, we tracked participants' motor movements while they decided whether to accept or reject gambles. Our results show that 1) mouse-tracking metrics of conflict sensitively detect differences in the subjective value of risky versus certain options; 2) these metrics of conflict strongly predict participants' risk preferences (loss aversion and decreasing marginal utility), even on a single-trial level; 3) these mouse-tracking metrics outperform participants' reaction times in predicting risk preferences; and 4) manipulating risk preferences via a broad versus narrow bracketing manipulation influences conflict as indexed by mouse tracking. Together, these results highlight the importance of measuring conflict during risky choice and demonstrate the usefulness of mouse tracking as a tool to do so.

Multifocal invasive mucinous carcinoma of the breast.

Mucinous carcinoma accounts for approximately 2% of all breast cancer and is a rare subtype of infiltrating ductal carcinoma. It often presents as a lobulated, well-circumscribed mass on mammography, sonography, and magnetic resonance imaging and can therefore be mistaken for a benign lesion. This case report discusses a rare case of multifocal invasive mucinous carcinoma of the breast detected on screening mammogram. The histological attributes and various imaging findings of mucinous breast cancer are then discussed.

Bisphenol S rapidly depresses heart function through estrogen receptor-ß and decreases phospholamban phosphorylation in a sex-dependent manner.

The health effects of the endocrine disruptor Bisphenol A (BPA) led to its partial replacement with Bisphenol S (BPS) in several products including food containers, toys, and thermal paper receipts. The acute effects of BPS on myocardial contractility are unknown. We perfused mouse hearts from both sexes for 15 min with physiologically relevant doses of BPS or BPA. In females BPS (1 nM) decreased left ventricular systolic pressure by 5 min, whereas BPA (1 nM) effects were delayed to 10 min. BPS effects in male mice were attenuated. In both sexes ER-ß antagonism abolished the effects of BPS. Cardiac myofilament function was not impacted by BPS or BPA in either sex, although there were sex-dependent differences in troponin I phosphorylation. BPS increased phospholamban phosphorylation at S16 only in female hearts, whereas BPA reduced phosphorylation in both sexes. BPA decreased phospholamban phosphorylation at T17 in both sexes while BPS caused dephosphorylation only in females. This is the first study to compare sex differences in the acute myocardial response to physiologically relevant levels of BPS and BPA, and demonstrates a rapid ability of both to depress heart function. This study raises concerns about the safety of BPS as a replacement for BPA.

Cardiac changes during the peri-menopausal period in a VCD-induced murine model of ovarian failure.

AIM: Cardiovascular disease (CVD) risk is lower in pre-menopausal females vs age matched males. After menopause risk equals or exceeds that of males. CVD protection of pre-menopausal females is ascribed to high circulating oestrogen levels. Despite experimental evidence that oestrogen are cardioprotective, oestrogen replacement therapy trials have not shown clear benefits. One hypothesis to explain the discrepancy proposed hearts remodel during peri-menopause. Peri-menopasual myocardial changes have never been investigated, nor has the ability of oestrogen to regulate heart function during peri-menopause. METHODS: We injected female mice with 4-vinylcyclohexene diepoxide (VCD, 160 mg/kg/d IP) to cause gradual ovarian failure over 120d and act as a peri-menopausal model RESULTS: Left ventricular function assessed by Langendorff perfusion found no changes in VCD-injected mice at 60 or 120 days compared to intact mice. Cardiac myofilament activity was altered at 60 and 120 days indicating a molecular remodelling in peri-menopause. Myocardial TGF-ß1 increased at 60 days post-VCD treatment along with reduced Akt phosphorylation. Acute activation of oestrogen receptor-α (ERα) or -ß (ERß) depressed left ventricular contractility in hearts from intact mice. ER-regulation of myocardial and myofilament function, and myofilament phosphorylation, were disrupted in the peri-menopausal model. Disruption occurred without alterations in total ERα or ERß expression. CONCLUSIONS: This is the first study to demonstrate remodelling of the heart in a model of peri-menopause, along with a disruption in ER-dependent regulation of the heart. These data indicate that oestrogen replacement therapy initiated after menopause affects a heart that is profoundly different from that found in reproductively intact animals.

Believability of evidence matters for correcting social impressions.

To what extent are we beholden to the information we encounter about others? Are there aspects of cognition that are unduly influenced by gossip or outright disinformation, even when we deem it unlikely to be true? Research has shown that implicit impressions of others are often insensitive to the truth value of the evidence. We examined whether the believability of new, contradictory information about others influenced whether people corrected their implicit and explicit impressions. Contrary to previous work, we found that across seven studies, the perceived believability of new evidence predicted whether people corrected their implicit impressions. Subjective assessments of truth value also uniquely predicted correction beyond other properties of information such as diagnosticity/extremity. This evidence shows that the degree to which someone thinks new information is true influences whether it impacts implicit impressions.

Updating implicit impressions: New evidence on intentionality and the affect misattribution procedure.

Recent work has shown that implicit first impressions of other people can be rapidly updated when new information about them is highly diagnostic or provides a reinterpretation of the basis of prior belief. The Affect Misattribution Procedure (AMP; Payne, Cheng, Govorun, & Stewart, 2005) is one prominent implicit measure that has been widely used in this and other work. However, the status of the AMP as a measure of unintentional responding has been a matter of debate, which necessarily also raises questions about the "implicitness" of the updated responses within recent person impression research. In re-analyses of published work, we identify multimodal distributions of AMP responses that raise concerns about potential intentional influences on this task. Drawing on 8 new studies, however, we find that such patterns are not likely attributable to intentional responding (Studies 1, 2A-2B), and that methodological modifications to the AMP procedure eliminate bimodality but do not eliminate effects of rapid revision (Studies 3A-6). Furthermore, these modifications provide evidence that the rapid-revision effects reported in earlier work can be produced under suboptimal conditions such as distraction and increased vigilance against prime influence. We advocate for the continued use of judgmental misattribution as a valuable tool in the arsenal of implicit social cognition researchers, but also encourage researchers to continue to examine the distributional patterns of measures like the AMP, and what those patterns might reflect. (PsycINFO Database Record (c) 2019 APA, all rights reserved).