RESUMO
Various dermatoses have been described associated with rheumatoid arthritis. Recently, a specific cutaneous lesion termed "intravascular histiocytosis" has been proposed as a new entity among these dermatoses. We report the case of a 50-year-old woman with rheumatoid arthritis for about 10 years who developed erythematous patches on the extensor surface of lower extremities. Histopathologically, the lesions showed intraluminal proliferation of CD68-positive histiocytes in vessels lined with endothelial cells expressing D2-40, a selective marker for lymphatic endothelium.
Assuntos
Anticorpos Monoclonais , Artrite Reumatoide/complicações , Histiocitose/imunologia , Imuno-Histoquímica/métodos , Dermatoses da Perna/imunologia , Vasos Linfáticos/imunologia , Anticorpos Monoclonais Murinos , Antígenos CD/análise , Antígenos de Diferenciação Mielomonocítica/análise , Artrite Reumatoide/imunologia , Artrite Reumatoide/patologia , Proliferação de Células , Derme/imunologia , Derme/patologia , Eritema/etiologia , Eritema/imunologia , Feminino , Histiócitos/imunologia , Histiócitos/patologia , Histiocitose/diagnóstico , Histiocitose/etiologia , Histiocitose/patologia , Humanos , Dermatoses da Perna/diagnóstico , Dermatoses da Perna/etiologia , Dermatoses da Perna/patologia , Vasos Linfáticos/patologia , Pessoa de Meia-IdadeRESUMO
BACKGROUND: Heterotopic islands of salivary tissue are commonly found in the intraparotid lymph nodes and, less commonly, within extraparotid cervical nodes. Salivary gland tumors, both benign and malignant, can develop within this ectopic salivary tissue. CASES: Two patients presented with a solitary, painless mass in the cervical region. Fine needle aspiration cytology was performed, and the smears revealed a mixture of intermediate and mucus-secreting cells associated with extracellular mucin. The tumors were removed, and the diagnosis of mucoepidermoid carcinoma was confirmed by histologic study. CONCLUSION: The finding of a malignant cervical salivary gland tumor does not necessarily represent a metastasis from an occult site.
Assuntos
Carcinoma Mucoepidermoide/patologia , Coristoma/patologia , Linfonodos/patologia , Neoplasias das Glândulas Salivares/patologia , Adulto , Biópsia por Agulha , Carcinoma Mucoepidermoide/cirurgia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Pescoço , Neoplasias das Glândulas Salivares/cirurgia , Resultado do TratamentoRESUMO
OBJECTIVE: To assess the utility of fine needle aspiration cytology in the diagnosis of sialadenitis with crystalloid formation. STUDY DESIGN: In 15 cases, salivary gland masses were aspirated using a disposable, 20-mL syringe and 25-gauge needles, maintaining negative pressure. Smears routinely were air dried and stained by Diff-Quik (Dade Behring AG, Düdingen, Germany). Occasionally smears were fixed in alcohol and stained by the Papanicolaou method. RESULTS: The smears showed large numbers of non-birefringent crystalloids of varying sizes and shapes. The crystalloids stained deep blue with Diff-Quik and bright orange with Papanicolaou stain. Multinucleated histiocytes, neutrophilic leukocytes and benign salivary gland parenchyma were found, also. CONCLUSION: Fine needle aspiration cytology provides an accurate diagnosis of sialadenitis with crystalloids and is useful for avoiding unnecessary surgery.