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J Environ Radioact ; 127: 182-90, 2014 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-23465891

RESUMO

The paper deals with effects of the ionising radiation (γ-IR, 0.5 Gy) upon serum testosterone (T), characteristics of testosterone-binding globulin (TeBG) and androgen receptor (AR) in parallel with observation of androgen (A) responsive enzyme activity - hexokinase (HK). The interdependence or relationships of T-levels with parameters of the proteins that provide androgenic regulation are consequently analyzed in post-IR dynamics. The IR-stress adjustment data reveal expediency of TeBG- and AR-cooperativity measurements for more precise assessments of endocrine A-control at appropriate emergencies.


Assuntos
Raios gama/efeitos adversos , Hexoquinase/sangue , Receptores Androgênicos/sangue , Animais , Relação Dose-Resposta à Radiação , Masculino , Ratos , Ratos Wistar , Globulina de Ligação a Hormônio Sexual/análise , Testosterona/sangue
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