Near-Peer Teaching in Radiation Oncology: a Proof of Principle Study for Learning Treatment Planning.

Radiotherapy techniques are expanding in range and complexity; therefore, protecting learning environments where residents nurture treatment planning skills is critical. The evidence base for 'near-peer' teaching (NPT), where professionals at a similar career stage assist in each other's learning, is growing in hospital-based disciplines, but has not been reported in radiation oncology. The feasibility of a resident-led teaching programme for developing treatment planning skills was investigated herein with quality improvement (QI) methodology. Following consultation with attendings (n = 10) and all residents (n = 17) at the two cancer centres in the region, a regular NPT session focused on planning skills was initiated at the largest centre, with video-linking to the second centre. Tutorials were case-based and pitched at the level of qualifying examinations. Plan-Do-Study-Act (PDSA) cycles were designed based on primary and secondary improvement drivers derived by group consensus among residents, with tutorials adopted accordingly. Participation, content, and satisfaction were monitored for 20 months. Six PDSA cycles reformed the tutorial format, leading to logistical and pedagogical benefits including interprofessional contributions and enhanced interactivity. Tutorials occurred on 85% prescribed occasions (n = 45) during the subsequent 18-month follow-up, with 25 distinct tumour sites featured. Resident participation and satisfaction increased, independent of resident seniority. Tutorials were paused for the first 2 months of the SARS-CoV-2 pandemic only. A high-quality and cost-effective regional, trainee-led teaching programme on treatment planning was feasible and cost-effective in this study.

Perceptions of Psychological Abuse: The Role of Perpetrator Gender, Victim's Response, and Sexism.

It is commonly assumed that male abuse is more damaging than female abuse, just as it previously has been assumed that physical abuse is more harmful than psychological abuse. We sought to examine gender assumptions given that they may cause people to overlook the harm that men experience with a psychologically abusive partner. The current experiment compared perceptions of male and female perpetrators of psychological abuse, and examined whether gendered perceptions were affected by sexist beliefs or participants' own sex. The experiment also explored the effect of the victim's response to a perpetrator's abuse. College participants (N = 195) read a scenario depicting a hypothetical marital conflict that manipulated the sex of the perpetrator, the level of abuse (abuse or no abuse), and whether the victim did or did not respond with some aggression. In scenarios that featured abuse (relative to no-abuse conditions), a male perpetrator was consistently perceived more harshly than a female perpetrator. Participant sex and sexism did not moderate this gender-based perception. Varying the victim's response in the scenario affected perceptions more in the no-abuse condition than in the abuse condition. The findings are discussed in terms of robust gender assumptions and the difficulties in challenging such assumptions.

Characterizing computer-mediated communication, friendship, and social participation in adults with traumatic brain injury.

BACKGROUND: Adults with traumatic brain injury (TBI) report loss of friendship and reduced social participation after injury, but there is limited information regarding quantity of friends and methods of communication. Our objective was to characterize friendship networks, social participation, and methods of communication, including computer-mediated communication (CMC), used by adults with TBI compared to uninjured adults. METHODS: Participants were 25 adults with TBI and 26 uninjured healthy comparisons (HC) adults, who completed the Participation Assessment with Recombined Tools-Objective (PART-O) and the Social Network Questionnaire (SNQ). RESULTS: Adults with TBI had significantly fewer total friends and significantly lower levels of productivity and overall social participation. Face-to-face interaction was the preferred method of contact for both groups. Adults with TBI were significantly less likely to use texting as a primary method of communication than their uninjured peers, but used other methods of communication at similar rates. CONCLUSION: Our study supports prior findings of reduced friendships and reduced social participation after TBI and adds new information about similarities and differences in communication methods between adults with and without TBI.

Friendship Quality, Friendship Quantity, and Social Participation in Adults with Traumatic Brain Injury.

Adults with traumatic brain injury (TBI) often report reduced social participation and loss of friends, but little is known about quality of friendship after TBI. Our objective was to characterize social participation, friendship quantity, and friendship quality of adults with TBI and a comparison group of uninjured adults. Participants included 18 adults with moderate to severe TBI and 16 of their informant friends; and 18 uninjured adults and 11 of their informant friends. The main measures used were the Participation Assessment with Recombined Tools-Objective, the Social Network Questionnaire, and the McGill Friendship Questionnaire. Participants with TBI reported significantly less social participation and had fewer total friends, although this difference was not statistically significant. Adults with TBI differed from their friends on one measure of friendship quality, but reports for friendship quality were high in both groups. Adults with TBI reported overall high levels of friendship quality despite having lower levels of social participation compared with uninjured adults. Future research should investigate how the balance of quantity and quality of friendships relates to satisfaction with social participation and overall quality of life.

Interrelationship of homocysteine-cobalamin-folate indices in human subjects of various ages: can hyper-homocyteinemia be relieved with B-12 supplementation?

OBJECTIVE: To find the effect of aging, nutrition, and gender on Homocysteine-Cobalamin-Folate (HCF) Triad and to determine if B-12 supplementation decreases high levels of homocysteine. METHODS: In 192 subjects, blood indices were determined to study the relationship of HCF triad to age and gender, 28 had low holotranscobalmin (TC II), and five had low serum cobalamin. Thirty-nine of the subjects who had hyperhomocysteinemia were daily given 100 mcg B-12 for three months. RESULTS: Thirty-six subjects with hyperhomocysteinemia exhibited different responses based on baseline serum B-12 levels. Those with serum B-12 < 350 pg/ml decreased homocysteine and increased red blood cell (RBC) folate. The serum folate was not significantly changed. Those with B-12 > 350 pg/ml exhibited increase in RBC folate only. CONCLUSION: B-12 supplementation is effective in alleviating hyperhomocysteinemia. Compared to men, aging women had lower homocysteine.

Transcobalamin II 775G>C polymorphism and indices of vitamin B12 status in healthy older adults.

A common polymorphism (775G>C) in the vitamin B12 transport protein, transcobalamin II (TCII), has been identified in which proline replaces arginine at codon 259. We determined the influence of TCII genotype on indices of B12 status, including total serum B12, the amount of B12 bound to TCII (holoTCII), methylmalonic acid, and homocysteine, in 128 healthy older adults (ages 40-88 years). Mean total B12 and homocysteine concentrations were not significantly different among the 3 genotypes. Mean holoTCII concentration was significantly higher in those subjects homozygous for the proline form of TCII (PP) compared with those homozygous for the arginine form (RR) and heterozygotes (PR) (P