1.
Blood
; 143(12): 1193-1197, 2024 Mar 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38237140
RESUMO
ABSTRACT: Many patients with antiphospholipid syndrome had decreased ectonucleotidase activity on neutrophils and platelets, which enabled extracellular nucleotides to trigger neutrophil-platelet aggregates. This phenotype was replicated by treating healthy neutrophils and platelets with patient-derived antiphospholipid antibodies or ectonucleotidase inhibitors.