Accelerated wear testing shows that thermoplastic bushings could be a cost-effective and durable alternative to traditional bearings for wheelchair caster use.

Introduction: Wheelchair caster bearings often suffer high-risk failures that lead to adverse consequences such as user injuries, suggesting that design improvements are necessary. This study aimed to compare thermoplastic bushings to standard roller bearings for potential improvements in durability and cost-effectiveness. Methods: The durability and cost-effectiveness of two thermoplastic bushing models and two metallic ball-bearing models were tested using a standard lab-based accelerated wear testing protocol. Bushings and bearings were installed on a standard 8″ caster, and four samples per model underwent testing (16 total samples). Results: All failures were experienced by the stem rolling element. The thermoplastic bushings experienced higher mean durability than the standard ball-bearings. There were significant differences in durability across the tested models, F(3,12) = 3.88, p = 0.04. The durability of thermoplastic bushing #2 was higher than the standard type ZZ shielded deep groove ball bearings, p < 0.05. There were significant differences in cost-effectiveness across the tested models, F(3,12) = 7.64, p = 0.004. The cost-effectiveness of both thermoplastic bushings were significantly higher compared to type 2RS sealed deep groove bearings, p < 0.05. Conclusions: The use of thermoplastic bushings can lower product cost and potentially reduce caster failures in the community that are associated with adverse consequences including user injuries.

PET Imaging of Leg Arteries for Determining the Input Function in PET/MRI Brain Studies Using a Compact, MRI-compatible PET System.

In this study, we used a compact, high-resolution, and MRI-compatible PET camera (VersaPET) to assess the feasibility of measuring the image-derived input function (IDIF) from arteries in the leg with the ultimate goal of enabling fully quantitative PET brain imaging without blood sampling. We used this approach in five 18F-FDG PET/MRI brain studies in which the input function was also acquired using the gold standard of serial arterial blood sampling. After accounting for partial volume, dispersion, and calibration effects, we compared the metabolic rates of glucose (MRglu) quantified from VersaPET IDIFs in 80 brain regions to those using the gold standard and achieved a bias and variability of <5% which is within the range of reported test-retest values for this type of study. We also achieved a strong linear relationship (R2 >0.97) against the gold standard across regions. The results of this preliminary study are promising and support further studies to optimize methods, validate in a larger cohort, and extend to the modeling of other radiotracers.