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1.
J Small Anim Pract ; 60(5): 313-318, 2019 May.
Artigo em Inglês | MEDLINE | ID: mdl-30430575

RESUMO

OBJECTIVES: To determine whether artificial urethral sphincter filling volume is proportional to peak pressure exerted on the urethra. MATERIALS AND METHODS: Urethral pressure profilometry was performed in five female, medium-sized, mixed-breed canine cadavers following artificial urethral sphincter placement. Maximum urethral pressure was recorded following sequential incremental inflation of 0.15 mL and compared to baseline pressure and between dogs using two-way analysis of variance. RESULTS: Artificial urethral sphincter placement in cadavers was associated with an increase in urethral pressure, which was significantly correlated with inflation volume. The correlation was non-linear and demonstrated considerable individual variation. Maximum urethral pressures after artificial urethral sphincter placement exceeded those reported in conscious continent dogs within a narrow volume range, in which a 0.15 mL infusion more than doubled maximal urethral pressures. CLINICAL SIGNIFICANCE: Rapid increases in urethral pressure from the artificial urethral sphincter over a small range of filling volumes (0.15 mL increments) might explain why some clinical cases can become suddenly dysuric following incremental inflations. We suggest that smaller increments of filling (0.05 to 0.1 mL) may achieve finer pressure control.


Assuntos
Uretra , Esfíncter Urinário Artificial , Animais , Cadáver , Doenças do Cão , Cães , Disuria/veterinária , Feminino , Masculino
2.
Artigo em Inglês | MEDLINE | ID: mdl-29094784

RESUMO

Advances in cancer care delivery require revision and further development of questionnaires assessing patients' perceived quality of care. This study pre-tested the revised EORTC satisfaction with cancer care core questionnaire applicable in both the cancer inpatient and outpatient settings, and its new, outpatient-specific complementary module. The process of revision, development of the extended application, and pre-testing of these questionnaires was based on phases I to III of the "EORTC Quality of Life Group Module Development Guidelines." In phase III, patients in 11 countries in four European regions, South America and Asia completed provisional versions of the questionnaires. Fifty-seven relevant issues selected from literature reviews and input from experts were operationalized into provisional items, and subsequently translated into ten languages. Assessment of understanding, acceptability, redundancy and relevance by patients (n = 151) from oncology inpatient wards, and outpatient chemotherapy, radiotherapy and consultation settings, led to retention of, deletion of and merging of 40, 14 and 6 items respectively. Cronbach's alpha coefficients for hypothesized questionnaire scales were above 0.80. Our results provide preliminary support for the 33-item EORTC Satisfaction with cancer care core questionnaire and the 7-item complementary module specific for the outpatient care setting. A large scale phase IV cross-cultural psychometric study is now underway.


Assuntos
Neoplasias/terapia , Satisfação do Paciente , Idoso , Assistência Ambulatorial , Europa (Continente) , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Sociedades Médicas , Inquéritos e Questionários
3.
J Small Anim Pract ; 58(12): 703-708, 2017 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-28963795

RESUMO

OBJECTIVES: To report the prevalence of abnormal fluoroscopic findings in brachycephalic dogs that were presented to a referral hospital for obstructive airway syndrome. METHODS: Hospital records between May 2013 and November 2015 identified 36 brachycephalic dogs investigated for obstructive airway disease: 21 French bulldogs, six bulldogs, four Boston terriers, two pugs, two boxers and one shih-tzu. The presence or absence of hiatal hernia, delayed oesophageal transit, gastro-oesophageal reflux and redundant oesophagus were recorded. RESULTS: Of the 36 dogs, 16 had hiatal hernia, all of which were French bulldogs; 31 dogs had delayed oesophageal transit time, 27 had gastro-oesophageal reflux, and four had redundant oesophagus. CLINICAL SIGNIFICANCE: Clinical Significance: The prevalence of hiatal hernia is higher than expected in the French bulldog, and there was a high prevalence of oesophageal disease in this group in general. These results suggest a need to investigate similar cases for evidence of gastrointestinal disease that may also require attention.


Assuntos
Craniossinostoses/veterinária , Doenças do Cão/epidemiologia , Esôfago/anormalidades , Hérnia Hiatal/veterinária , Obstrução das Vias Respiratórias/veterinária , Animais , Craniossinostoses/epidemiologia , Doenças do Cão/diagnóstico por imagem , Cães , Esôfago/diagnóstico por imagem , Fluoroscopia/veterinária , Refluxo Gastroesofágico/epidemiologia , Refluxo Gastroesofágico/veterinária , Hérnia Hiatal/diagnóstico por imagem , Hérnia Hiatal/epidemiologia , Humanos , Masculino , Prevalência
4.
Br J Cancer ; 115(9): 1032-1038, 2016 Oct 25.
Artigo em Inglês | MEDLINE | ID: mdl-27673364

RESUMO

BACKGROUND: There is no specific quality of life (QoL) measurement tool to quantify QoL in patients with biliary tract cancer. Quality of life measurement is an increasingly crucial trial end point and is now being incorporated into clinical practice. METHODS: This International Multicentre Phase IV Validation Study assessed the QLQ-BIL21 module in 172 patients with cholangiocarcinoma and 91 patients with cancer of the gallbladder. Patients completed the questionnaire at baseline pretherapy and subsequently at 2 months. Following this, the psychometric properties of reliability, validity, scale structure and responsiveness to change were analysed. RESULTS: Analysis of the QLQ-BIL21 scales showed appropriate reliability with Cronbach's α-coefficients >0.70 for all scales overall. Intraclass correlations exceeded 0.80 for all scales. Convergent validity >0.40 was demonstrated for all items within scales, and discriminant validity was confirmed with values <0.70 for all scales compared with each other. Scale scores changed in accordance with Karnofsky performance status and in response to clinical change. CONCLUSIONS: The QLQ-BIL21 is a valid tool for the assessment of QoL in patients with cholangiocarcinoma and cancer of the gallbladder.


Assuntos
Neoplasias dos Ductos Biliares/psicologia , Colangiocarcinoma/psicologia , Neoplasias da Vesícula Biliar/psicologia , Qualidade de Vida , Inquéritos e Questionários , Adulto , Idoso , Neoplasias dos Ductos Biliares/diagnóstico , Neoplasias dos Ductos Biliares/terapia , Ductos Biliares Intra-Hepáticos/patologia , Colangiocarcinoma/diagnóstico , Colangiocarcinoma/terapia , Feminino , Neoplasias da Vesícula Biliar/diagnóstico , Neoplasias da Vesícula Biliar/terapia , Humanos , Masculino , Pessoa de Meia-Idade , Prognóstico , Psicometria , Reprodutibilidade dos Testes , Resultado do Tratamento
5.
Qual Life Res ; 25(3): 595-604, 2016 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-26353905

RESUMO

PURPOSE: To investigate patients' and health professionals' understanding of and preferences for different graphical presentation styles for individual-level EORTC QLQ-C30 scores. METHODS: We recruited cancer patients (any treatment and diagnosis) in four European countries and health professionals in the Netherlands. Using a questionnaire, we assessed objective and self-rated understanding of QLQ-C30 scores and preferences for five presentation styles (bar and line charts, with or without color coding, and a heat map). RESULTS: In total, 548 patients and 227 health professionals participated. Eighty-three percent of patients and 85 % of professionals self-rated the graphs as very or quite easy to understand; this did not differ between graphical presentation styles. The mean percentage of correct answers to questions objectively assessing understanding was 59 % in patients, 78 % in medical specialists, and 74 % in other health professionals. Objective understanding did not differ between graphical formats in patients. For non-colored charts, 49.8 % of patients did not have a preference. Colored bar charts (39 %) were preferred over heat maps (20 %) and colored line charts (12 %). Medical specialists preferred heat maps (46 %) followed by non-colored bar charts (19 %), whereas these charts were equally valued by other health professionals (both 32 %). CONCLUSION: The substantial discrepancy between participants' high self-rated and relatively low objective understanding of graphical presentation of PRO results highlights the need to provide sufficient guidance when presenting such results. It may be appropriate to adapt the presentation of PRO results to individual preferences. This could be facilitated when PROs are administered and presented to patients and health professionals electronically.


Assuntos
Atitude do Pessoal de Saúde , Compreensão , Gráficos por Computador , Indicadores Básicos de Saúde , Avaliação de Resultados da Assistência ao Paciente , Preferência do Paciente/estatística & dados numéricos , Qualidade de Vida , Adulto , Idoso , Idoso de 80 Anos ou mais , Estudos Transversais , Europa (Continente) , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Neoplasias , Países Baixos
6.
J Small Anim Pract ; 56(3): 218-22, 2015 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-25223636

RESUMO

A new technique for autogenous chest wall reconstruction using a latissimus dorsi muscle flap and a free graft of thoracolumbar fascia was utilised in a two-year-old Dobermann after resection of a high-grade osteosarcoma from the left thoracic wall. En bloc excision of the chest wall mass, including six ribs, was performed. The resulting chest wall defect was too large to be reconstructed with only a pedicled muscle flap and was reconstructed with a latissimus dorsi muscle flap cranially and a free graft of thoracolumbar fascia caudally. The graft was harvested easily, and there was no donor site morbidity or postoperative complications. A free graft of thoracolumbar fascia can be considered as an option to supplement autogenous reconstruction of the chest wall.


Assuntos
Músculos do Dorso/transplante , Doenças do Cão/cirurgia , Músculos Superficiais do Dorso/transplante , Parede Torácica/cirurgia , Animais , Cães/cirurgia , Masculino , Procedimentos de Cirurgia Plástica/veterinária
8.
J Small Anim Pract ; 55(2): 84-8, 2014 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-24329725

RESUMO

OBJECTIVES: Feline injection site sarcomas are therapeutically challenging because of their locally invasive nature. Several protocols recommend that the two perceived high-risk adjuvanted vaccines should be administered into distinct anatomical sites ("left hind leg leukaemia, right hind leg rabies"), which should aid surgical resection. This has resulted in a change in tumour distribution with an increased proportion situated caudal to the diaphragm when such a policy is adopted. The aim of this study was to determine UK cat owners' attitudes towards surgical treatments of different anatomical regions. METHODS: A cross-sectional study of an anonymous convenience sample of UK cat owners was conducted from September to December, 2012 using an internet-based survey. RESULTS: There were a total of 208 respondents: 39% would pursue surgery regardless of tumour site. One percent would not pursue surgery. Of the remainder, respondents would not allow amputation of the forelimb (20%), hindlimb (15%) or tail (15%). Twenty-six, 32 and 27% would not have surgical treatment of the inter-scapular region, chest or abdomen, respectively. The majority of respondents were willing to travel up to 100 miles for radiotherapy or chemotherapy (66 and 69%, respectively). CLINICAL SIGNIFICANCE: The current feline vaccine site recommendations may not be appropriate for UK cat owners.


Assuntos
Doenças do Gato/terapia , Comportamento do Consumidor/estatística & dados numéricos , Injeções/veterinária , Sarcoma/veterinária , Neoplasias de Tecidos Moles/veterinária , Amputação Cirúrgica/veterinária , Animais , Doenças do Gato/cirurgia , Gatos , Estudos Transversais , Feminino , Humanos , Injeções/efeitos adversos , Masculino , Pessoa de Meia-Idade , Propriedade , Sarcoma/etiologia , Sarcoma/terapia , Neoplasias de Tecidos Moles/etiologia , Neoplasias de Tecidos Moles/cirurgia , Neoplasias de Tecidos Moles/terapia , Inquéritos e Questionários , Reino Unido
9.
J Small Anim Pract ; 54(8): 432-6, 2013 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-23659267

RESUMO

Anal sac gland carcinoma arising from the apocrine secretory epithelium in the anal sac wall, is locally invasive and highly metastatic. The majority of anal sac gland carcinomas are unilateral on presentation, but bilateral tumours have been identified. This case series presents the outcome of four unique cases of unilateral anal sac gland carcinoma which subsequently developed contralateral anal sac gland carcinoma 50 to 390 days after removal of the initial tumour. Median survival was 1035 days after initial diagnosis and 807 days after diagnosis of the second anal sac gland carcinoma.


Assuntos
Adenocarcinoma/veterinária , Neoplasias das Glândulas Anais/patologia , Sacos Anais/patologia , Doenças do Cão/patologia , Adenocarcinoma/diagnóstico , Adenocarcinoma/patologia , Adenocarcinoma/cirurgia , Neoplasias das Glândulas Anais/diagnóstico , Neoplasias das Glândulas Anais/cirurgia , Sacos Anais/cirurgia , Animais , Doenças do Cão/diagnóstico , Doenças do Cão/cirurgia , Cães , Evolução Fatal , Feminino , Masculino
11.
Vet Rec ; 171(13): 326, 2012 Sep 29.
Artigo em Inglês | MEDLINE | ID: mdl-22892401

RESUMO

Veterinary practices in the United Kingdom were surveyed to compare their surgical draping practices with Royal College of Veterinary Surgeons (RCVS) accreditation tier and other surgery-related factors. Using descriptive statistics and logistic or ordinal regression analysis (where appropriate), the relationships between draping material and accreditation tier and other surgery-related factors were assessed. Procedures were categorised as short or long. Two hundred and sixty-nine surveys were completed. Reusable drapes were used in 66 per cent of practices. Antibiotics were administered routinely in 38 per cent of short and 93 per cent of long procedures. Practices accredited as a Veterinary Hospital (VH) were 6.3-7.2 (short and long surgeries, respectively) times more likely to use disposable drapes, when compared with non-accredited practices. Use of dedicated surgical attire, draping the whole animal/table, and routine antibiotic usage were also positively correlated with disposable drape usage. Fifty-one per cent of practices rated infection rate as most important when choosing drape material. 'Best practice' techniques are associated with lower importance given to infection rate, and higher importance given to financial cost, when choosing drape material. Disposable drape use correlates with RCVS accreditation and with other aspects of surgical technique. Importance ratings awarded correlate with best practice procedures. Clinical relevance 'Best practice' draping procedures, that are not governed by RCVS accreditation scheme, are also more frequently performed in accredited VHs.


Assuntos
Roupas de Cama, Mesa e Banho/veterinária , Custos e Análise de Custo/estatística & dados numéricos , Infecção Hospitalar/veterinária , Cirurgia Veterinária/instrumentação , Cirurgia Veterinária/estatística & dados numéricos , Acreditação , Animais , Roupas de Cama, Mesa e Banho/economia , Roupas de Cama, Mesa e Banho/estatística & dados numéricos , Infecção Hospitalar/prevenção & controle , Equipamentos Descartáveis/economia , Equipamentos Descartáveis/estatística & dados numéricos , Equipamentos Descartáveis/veterinária , Medicina Baseada em Evidências , Humanos , Roupa de Proteção/economia , Roupa de Proteção/estatística & dados numéricos , Roupa de Proteção/veterinária , Cirurgia Veterinária/economia , Cirurgia Veterinária/normas , Reino Unido
12.
J Small Anim Pract ; 53(6): 338-43, 2012 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-22647212

RESUMO

OBJECTIVE: To review the postoperative results and complications associated with urethral sphincter mechanism incompetence managed with a static hydraulic urethral sphincter. METHODS: Case records and a telephone owner questionnaire were retrospectively used to assess postoperative urinary continence scores (1 - dripping constantly to 10 - completely dry) and presence and frequency of complications. RESULTS: Eleven spayed females were included. Median continence score/10 (range) awarded preoperatively was 3 (2 to 6), and scores at two weeks, three and six months were 8 (4 to 10), 9 (4 to 10) and 8 (4 to 10), respectively. At the last survey, the median continence score of 9 (5 to 10) was significantly better (P=0·004) than before surgery. Complete continence was achieved in 36·4% of dogs. The median (range) follow-up time was 412 (118 to 749) days. Complications occurred in 9 of 11 dogs and included dysuria (n=7), bacterial cystitis (n=7), longer urination time (n=8), urinary retention (n=3), haematuria (n=1), pain (n=3) and incisional seroma (n=3). CLINICAL SIGNIFICANCE: Static hydraulic urethral sphincter was frequently associated with minor complications but no major complications (i.e. those requiring further surgery). Continence scores were significantly improved compared with those before surgery, with the possibility of further improvement following inflation of the sphincter.


Assuntos
Doenças do Cão/cirurgia , Complicações Pós-Operatórias/veterinária , Incontinência Urinária/veterinária , Esfíncter Urinário Artificial/veterinária , Animais , Cães , Feminino , Complicações Pós-Operatórias/epidemiologia , Reoperação/veterinária , Estudos Retrospectivos , Resultado do Tratamento , Incontinência Urinária/cirurgia
13.
Transbound Emerg Dis ; 59(3): 279-81, 2012 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-21999899

RESUMO

Vitamin D insufficiency is regularly observed in human patients with tuberculosis but it is unknown if spontaneous mycobacteria infections in other species are associated with suboptimal vitamin D status. Serum 25 hydroxyvitamin D (25(OH)D) concentrations were significantly lower in cats with mycobacteriosis than in healthy cats (P < 0.001).


Assuntos
Doenças do Gato/sangue , Infecções por Mycobacterium/veterinária , Vitamina D/análogos & derivados , Animais , Gatos , Infecções por Mycobacterium/sangue , Vitamina D/sangue
14.
J Small Anim Pract ; 52(11): 587-94, 2011 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-22026742

RESUMO

OBJECTIVES: To investigate the development of surgical skills of veterinary undergraduates and determine the number of canine ovariohysterectomies required to achieve competency and reduce levels of student concern. This was compared to student expectations and that of employers regarding surgical ability and provision of support to new graduates. METHODS: A questionnaire regarding surgical concerns was sent to final year veterinary students enrolled within the University of Bristol, UK. A questionnaire was also sent to 200 UK veterinary practices regarding their impressions of surgical competence of new graduates and their provision of supervision. The responses were compared. Eleven additional final year students performed five canine ovariohysterectomies and graded their concerns. The number of supervised canine ovariohysterectomies required until competency was determined. RESULTS: 80·4% of final year veterinary undergraduates replied that the surgical procedure which they were most concerned about their ability to perform was canine ovariohysterectomy. Students and veterinary practitioners differed in their opinions regarding whether they considered canine ovariohysterectomy to be a "day one skill" and what were desirable levels of supervision. Completing a minimum of four canine ovariohysterectomies led to 81·8% of students being assessed as competent. CLINICAL SIGNIFICANCE: An unrealistically high expectation of competency by students may be a source of stress and concern. Employers should aim to provide hands-on support whilst new graduates complete at least four canine ovariohysterectomies. Postoperative haemorrhage is uncommon but is the main concern for students.


Assuntos
Competência Clínica , Educação em Veterinária/normas , Histerectomia/veterinária , Ovariectomia/veterinária , Estudantes de Medicina/psicologia , Animais , Educação Baseada em Competências , Cães , Feminino , Humanos , Histerectomia/efeitos adversos , Histerectomia/normas , Aprendizagem , Ovariectomia/efeitos adversos , Ovariectomia/normas , Hemorragia Pós-Operatória/epidemiologia , Hemorragia Pós-Operatória/veterinária , Inquéritos e Questionários
15.
J Small Anim Pract ; 52(11): 582-6, 2011 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-21985466

RESUMO

OBJECTIVES: To compare the mechanical properties of two different materials for canine median sternotomy closure. STUDY DESIGN: In vitro biomechanical study. SAMPLE POPULATION: Twelve canine cadaveric entire sternum and portion of associated ribs and musculature. METHODS: Median sternotomy leaving the manubrium intact was closed using polydioxanone and stainless steel wire in a figure of eight pattern. Constructs were loaded in a servohydraulic material testing system and displacement was compared at loads of 125, 150, 200, 250, 300, 350 and 400 N, and at failure. RESULTS: Displacement at loads up to 400 N and failure did not show any statistical difference between the polydioxanone and the stainless steel wire. However, the loading forces to create failure of the construct were superior for the stainless steel. Polydioxanone and stainless steel wire had the same response to distractive forces for loads applied up to 400 N. CLINICAL SIGNIFICANCE: This study cannot recommend the use of polydioxanone over wires but suggests that polydioxanone can potentially be an alternative for primary median sternotomy closure in selected patients.


Assuntos
Fios Ortopédicos , Cães/cirurgia , Polidioxanona , Esternotomia/veterinária , Estresse Mecânico , Técnicas de Sutura/veterinária , Animais , Cadáver , Teste de Materiais/veterinária , Aço Inoxidável , Esternotomia/instrumentação , Esternotomia/métodos , Esterno/cirurgia
16.
Br J Cancer ; 104(4): 587-92, 2011 Feb 15.
Artigo em Inglês | MEDLINE | ID: mdl-21266979

RESUMO

BACKGROUND: Quality of life measurement in cholangiocarcinoma and gallbladder cancer involves the assessment of patient-reported issues related to the symptoms, disease and treatment of these tumours. This study describes the development of the disease-specific quality of life (QoL) questionnaire for patients with cholangiocarcinoma and gallbladder cancer to supplement the European Organization for Research and Treatment of Cancer (EORTC)-QLQ C30 core cancer questionnaire. METHODS: Phases 1-3 of the guidelines for module development published by the EORTC were followed, with adaptations for incorporation of questions from existing modules. RESULTS: A total of 47 QoL issues (questions) were identified; 44 questions from the two related validated questionnaires, the EORTC QLQ-PAN26 (pancreatic module) and the EORTC QLQ-LMC21 (liver metastases module), two from the Functional Assessment of Cancer Therapy hepatobiliary module questionnaire in the literature search and one from healthcare professional interviews. Following phase 1 and 2 interviews with patients (n=101) and health care professionals (n=6), a 23-question provisional questionnaire was formulated. There were five questions from PAN26, 15 from LMC21 and three extra questions. In phase 3, the provisional item list was pre-tested in 52 patients in four languages and this resulted in a 21-item module. CONCLUSION: This is the only disease-specific QoL questionnaire for patients with cholangiocarcinoma and gallbladder cancer, and initial assessments show it to be accurate and acceptable to patients in reflecting QoL in these diseases.


Assuntos
Neoplasias dos Ductos Biliares/psicologia , Ductos Biliares Intra-Hepáticos , Colangiocarcinoma/psicologia , Neoplasias da Vesícula Biliar/psicologia , Qualidade de Vida , Inquéritos e Questionários , Adulto , Idoso , Idoso de 80 Anos ou mais , Neoplasias dos Ductos Biliares/epidemiologia , Neoplasias dos Ductos Biliares/patologia , Neoplasias dos Ductos Biliares/terapia , Ductos Biliares Intra-Hepáticos/patologia , Colangiocarcinoma/epidemiologia , Colangiocarcinoma/patologia , Colangiocarcinoma/terapia , Europa (Continente)/epidemiologia , Feminino , Neoplasias da Vesícula Biliar/epidemiologia , Neoplasias da Vesícula Biliar/patologia , Neoplasias da Vesícula Biliar/terapia , Humanos , Neoplasias Hepáticas/epidemiologia , Neoplasias Hepáticas/psicologia , Neoplasias Hepáticas/secundário , Neoplasias Hepáticas/terapia , Masculino , Pessoa de Meia-Idade , Qualidade de Vida/psicologia , Projetos de Pesquisa , Inquéritos e Questionários/normas , Estudos de Validação como Assunto
17.
Vet Rec ; 167(2): 55-8, 2010 Jul 10.
Artigo em Inglês | MEDLINE | ID: mdl-20622204

RESUMO

Otitis media with effusion (OME) is a common incidental finding in otherwise normal Cavalier King Charles spaniels (CKCS). In this study, measurements made on MRI were used to determine whether there was an association between OME and brachycephalic conformation. The results confirm that association and also demonstrate that, in CKCS, greater thickness of the soft palate and reduced nasopharyngeal aperture are significantly associated with OME. These results suggest that auditory tube dysfunction and OME may represent a previously overlooked consequence of brachycephalic conformation in dogs.


Assuntos
Doenças do Cão/etiologia , Nasofaringe/anatomia & histologia , Otite Média com Derrame/veterinária , Animais , Doenças do Cão/epidemiologia , Doenças do Cão/patologia , Cães , Tuba Auditiva/fisiopatologia , Incidência , Imageamento por Ressonância Magnética/veterinária , Otite Média com Derrame/epidemiologia , Otite Média com Derrame/etiologia , Palato Mole/anatomia & histologia , Fatores de Risco , Especificidade da Espécie
18.
Vet Rec ; 167(23): 895-9, 2010 Dec 04.
Artigo em Inglês | MEDLINE | ID: mdl-21262672

RESUMO

The concentrations of C-reactive protein (CRP), serum amyloid A, haptoglobin (Hp) and α(1)-acid glycoprotein were measured in dogs with clinical signs of nasal disease and compared with those of healthy dogs in order to determine the expression of these proteins in cases of canine nasal disease. A significant difference (P<0.001) between the symptomatic group and the control group was found for both CRP and Hp. Among the animals with nasal disease, a significant intergroup difference (P<0.05) was found in the expression of Hp between dogs with aspergillosis and those with chronic rhinitis.


Assuntos
Doenças do Cão/sangue , Doenças Nasais/veterinária , Proteínas de Fase Aguda , Animais , Aspergilose/sangue , Aspergilose/imunologia , Aspergilose/veterinária , Proteína C-Reativa/metabolismo , Estudos de Casos e Controles , Doenças do Cão/imunologia , Cães , Feminino , Haptoglobinas/metabolismo , Masculino , Doenças Nasais/sangue , Doenças Nasais/imunologia , Rinite/sangue , Rinite/imunologia , Rinite/veterinária , Proteína Amiloide A Sérica/metabolismo
19.
J Small Anim Pract ; 50(6): 298-300, 2009 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-19490377

RESUMO

A young dog was presented with a history of adopting an unusual posture to urinate, resulting in urine soaking of the ventral abdomen and caudal forelimbs. The dog was initially treated surgically with cranial advancement of the prepuce, which did not resolve the problem. Further surgery was then successfully carried out to create a more caudal preputial orifice, which angled the penis ventrally when extruded, directing urine away from the body. At follow-up clinical examination, the dog was clinically normal.


Assuntos
Cães/cirurgia , Pênis/cirurgia , Postura , Micção/fisiologia , Animais , Masculino , Resultado do Tratamento
20.
J Small Anim Pract ; 47(6): 312-5, 2006 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-16761982

RESUMO

OBJECTIVES: To evaluate the effect of short duration 1 per cent clotrimazole flush when combined with 1 per cent clotrimazole cream instilled into the frontal sinuses for the treatment of nasal aspergillosis in 14 dogs. METHODS: Fourteen dogs with clinical, radiological, serological and rhinoscopic findings consistent with nasal aspergillosis were treated by frontal sinus trephination and a short, five-minute flushing of 1 per cent topical clotrimazole solution followed by a 1 per cent clotrimazole cream instilled as a depot agent. RESULTS: Twelve of the 14 dogs (86 per cent) responded well to treatment and either had no clinical signs after treatment or had signs consistent with mild rhinitis during a minimum follow-up period of six months. Only one dog required multiple treatments. Treatment was well tolerated by all patients, with minimal complications. CLINICAL SIGNIFICANCE: This treatment compares favourably to previously published data using one-hour topical clotrimazole or enilconazole flushing treatment protocols. The treatment technique significantly reduced treatment time under anaesthesia.


Assuntos
Antifúngicos/administração & dosagem , Aspergilose/veterinária , Clotrimazol/administração & dosagem , Doenças do Cão/tratamento farmacológico , Doenças Nasais/veterinária , Administração Tópica , Animais , Aspergilose/tratamento farmacológico , Terapia Combinada , Doenças do Cão/patologia , Cães , Feminino , Seio Frontal , Masculino , Doenças Nasais/tratamento farmacológico , Estudos Prospectivos , Irrigação Terapêutica/veterinária , Resultado do Tratamento
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