[Multicentric B cell lymphoma in an 8-week-old calf]. / Multizentrisches B-Zell-Lymphom bei einem 8 Wochen alten Kalb.

The presented report describes a case of sporadic bovine leukosis and its disease progression in an 8-week old, male cross-breed calf (Red Holstein Fleckvieh). The calf was initially presented due to suspect pulmonary infection. However, generalized enlargement of the subcutaneous lymph nodes was noticed, which is untypical for this disease. Based on the hematologic findings of highly increased numbers of lymphoblasts in peripheral blood as well as the sonographic examination of the lymph nodes, sporadic bovine leukosis was suspected. The calf died suddenly, three weeks after initial presentation. Pathohistological examination revealed a high-degree enlargement of all lymph nodes as well as an infiltration of nearly all organs and tissues with a monomorphic round cell population. These cells were also detected in bone marrow cytology. Immunhistochemical examination was performed and the cells reacted positive for the B-cell markers Pax 5 and CD20. Virologic examination for enzootic bovine leukosis was negative. In conjunction with the diagnosis of multicentric B-cell lymphoma, the test results indicated a juvenile form of sporadic bovine lymphoma.

[Cutaneous neoplasia in cattle - diagnosis, treatment and follow up in 7 cases]. / Kutane Zubildungen beim Rind ­ Diagnose, Therapie und Verlaufskontrolle in 7 Fällen.

In two calves and five cows of various ages, cutaneous masses were detected. Initially, neoplasia was suspected. All masses were removed under local anesthesia, in some cases with additional sedation. Pathohistological examination was conducted subsequently. Benign neoplasia was diagnosed in 5 of the cases. In the 2 remaining cases, histopathology revealed non-neoplastic soft tissue proliferation and pyogranulomatous inflammation. All patients recovered well from surgery and continued to be profitable for 3 to 57 months.