Effect of hope therapy on fertility stress and pregnancy rate in infertile patients undergoing intrauterine insemination.

OBJECTIVE: To investigate the efficacy of hope therapy on fertility stress and pregnancy rate in infertile patients undergoing intrauterine insemination (IUI). METHODS: In this retrospective study, 180 infertile patients undergoing IUI during May 2017 and October 2019 were enrolled and grouped into a study group (n=90) receiving hope therapy and control group (n=90) receiving routine infertility care. The two groups were compared in terms of anxiety and depression, scores of Fertility Problem Inventory (FPI), scores of coping style, social support before and after intervention, and post-intervention hormone levels. RESULTS: (1) Hamilton Anxiety Scale (HAMA) and Hamilton Depression Scale (HAMD) scores showed no significant difference in both groups before intervention (P>0.05). After intervention, the study group exhibited lower scores of HAMA and HAMD than the control group (P<0.05). (2) The two groups showed no significant difference in FPI scale scores before intervention (P>0.05). After intervention, the study group exhibited lower scores of FPI than the control group (P<0.05). (3) The two groups had no significant difference in negative coping and positive coping scores before intervention (P>0.05). After intervention, the study group had lower negative coping scores and higher positive coping scores than the control group (P<0.05). (4) After intervention, the study group showed lower scores of obsessive-compulsive, interpersonal sensibility, depression, and anxiety, and significantly higher proportion of patients with SCL-90 positive factors regarding depression and anxiety than the control group (P<0.05). (5) The study group showed higher serum levels of luteinizing hormone (LH) and follicle stimulating hormone (FSH) than the control group after intervention (P<0.05). (6) The study group had a higher pregnancy rate than the control group at 6 months' follow-up (P<0.05). CONCLUSION: Hope therapy for infertile patients undergoing IUI can help improve their adverse mood, improve their fertility attitude, and improve pregnancy rate while decreasing the scores of depression, anxiety, and obsessive-compulsive factors.

The effects of comprehensive nursing intervention on the negative emotions of patients with infertility.

OBJECTIVE: To investigate the effects of comprehensive nursing intervention (CNI) on the negative emotions of patients with infertility. METHODS: A total of 132 patients were recruited as the study cohort and randomly divided into an observation group (n=62) and a control group (n=70). The patients in both groups underwent routine treatment and nursing. In addition, the patients in the observation group were administered CNI. The quality of life (QOL) scores and depression levels of all the patients were evaluated after the intervention. RESULTS: Before the CNI, the QOL scores and the anxiety and depression levels showed no significant differences between two the groups (P>0.05). After the intervention, the observation group showed much higher mild-depression and non-depression levels, higher mild-anxiety and non-anxiety levels and higher QOL and physiological function scores than the control group (all P<0.05). CONCLUSION: CNI has an effect on the negative emotions of patients with infertility.