Assuntos
Sarcoma Mieloide/cirurgia , Procedimentos Desnecessários , Neoplasias do Colo do Útero/cirurgia , Hemorragia Uterina/cirurgia , Feminino , Humanos , Histerectomia , Leucemia Mieloide Aguda/complicações , Leucemia Mieloide Aguda/tratamento farmacológico , Pessoa de Meia-Idade , Recidiva , Sarcoma Mieloide/complicações , Neoplasias do Colo do Útero/complicações , Hemorragia Uterina/etiologiaAssuntos
Doenças do Ceco/etiologia , Pseudo-Obstrução do Colo/complicações , Complicações Pós-Operatórias/etiologia , Adulto , Doenças do Ceco/diagnóstico por imagem , Cesárea , Feminino , Humanos , Histerectomia , Placenta Acreta/cirurgia , Complicações Pós-Operatórias/diagnóstico por imagem , Gravidez , Ruptura Espontânea/etiologia , Tomografia Computadorizada por Raios XRESUMO
Placentas of patients diagnosed with intrauterine growth restriction (IUGR) and intrauterine death (IUD) were examined by immunohistochemistry for alpha-beta subunits of human chorionic gonadotropin (hCG) and human placental lactogen (hPL) antibodies, and compared with placentas from women with healthy pregnancies. In total, 114 subjects were evaluated. The patient group comprised 27 cases of IUGR and 57 of IUD, and the control group consisted of 30 women with normal pregnancies. Placental specimens were examined for primary antibodies using immunohistochemical techniques. Placentas from 22 cases of IUGR were stained positively for alpha-hCG. All 27 specimens obtained from this group were stained positively for beta-hCG and hPL. Among the cases of IUD, 44 placentas were stained positively for alpha-hCG, and all 57 specimens were stained positively for beta-hCG and hPL.
Assuntos
Gonadotropina Coriônica/metabolismo , Morte Fetal/metabolismo , Retardo do Crescimento Fetal/metabolismo , Placenta/metabolismo , Lactogênio Placentário/metabolismo , Adolescente , Adulto , Consanguinidade , Feminino , Humanos , Imuno-Histoquímica , Recém-Nascido , Masculino , Gravidez , Adulto JovemRESUMO
We investigated the relationship between serum leptin concentration, serum lipid profile and other blood biochemistry parameters in healthy post-menopausal women. Blood samples for analysis of serum leptin concentration, blood biochemistry and hormonal status, and urine samples for calcium measurement were taken from 122 women. No significant correlation was found between serum leptin concentration and serum lipid profile. The concentration of serum leptin was significantly associated with body mass index (BMI), luteinizing hormone (LH) and alanine transaminase (ALT). BMI was found to be a statistically significant independent factor for serum leptin concentration. We conclude that leptin was not associated with serum lipids and lipoproteins in post-menopausal women. Leptin was associated with BMI, ALT and LH, however, with BMI being an independent predictor of leptin concentration. There was a relationship between LH and serum leptin concentration even after menopause, and ALT correlated with serum leptin concentration through BMI.