Is sense of coherence a predictor of lifestyle changes in subjects at risk for type 2 diabetes?

OBJECTIVE: To determine whether the sense of coherence (SOC) could predict the outcome of an 18-month lifestyle intervention program for subjects at risk of type 2 diabetes. METHODS: Subjects at high risk of type 2 diabetes mellitus were recruited to a low-intensity lifestyle intervention program by their general practitioners. Weight reduction ≥ 5% and improvement in exercise capacity of ≥ 10% from baseline to follow-up indicated a clinically significant lifestyle change. SOC was measured using the 13-item SOC questionnaire. RESULTS: The study involved 213 subjects with a mean body mass index of 37 (SD ± 6). Complete follow-up data were obtained for 131 (62%). Twenty-six participants had clinically significant lifestyle changes. There was a 21% increase in the odds of a clinically significant lifestyle change for each point increase in the baseline SOC score (odds ratio = 1.21; confidence interval = 1.11-1.32). The success rate was 14 times higher in the highest SOC score tertile group compared with the lowest. CONCLUSION: High SOC scores were good predictors of successful lifestyle change in subjects at risk of type 2 diabetes. SOC-13 can be used in daily practice to increase clinical awareness on the impact of mastery on the outcome of life-style intervention programs.

TB status among Kosovar refugees.

DESIGN: In the spring of 1999, 864 Kosovars were directly airborne from refugee camps in Macedonia to a refugee camp in Kristiansand, Norway; 800 were examined according to official Norwegian TB screening procedures with X-ray (if more than 15 years of age) and tuberculin test shortly after arrival. RESULTS: The mean (SD) age was 29.2 (18.7) years of age and 29% were aged under 15 years; 79% of the refugees had escaped from urban areas in Kosovo, and 75% had an identifiable BCG scar. Among those with BCG scar, increasing age and male sex were associated with a significant tuberculin reaction: 20% had tuberculin reactions indicating latent TB infection, while 40% had negative tuberculin reactions. Approximately 4% of the refugees aged over 15 had abnormal chest X-rays, predictive of an enhanced tuberculin reaction. Four refugees had X-ray findings compatible with active TB and were treated with standard four-drug chemotherapy. CONCLUSION: The Kosovar refugees had a high incidence of active tuberculosis (50/100,000). A fifth of the BCG-vaccinated refugees needed careful follow-up to monitor possible progress from latent to active TB infection after immigration, while one in seven non-BCG-vaccinated refugees had tuberculin skin reactions compatible with latent TB infection.

Cost-effectiveness of self-management in asthmatics: a 1-yr follow-up randomized, controlled trial.

Patient education in asthma can improve outcome but cost-effectiveness has not been widely assessed. The aim of the present study was to carry out a cost-effectiveness analysis of patient education in asthmatics in a 12-month follow-up. The authors randomly allocated 78 asthmatics to a control or intervention group after they had received ordinary outpatient consultation care. Intervention consisted of two 2-h group sessions followed by 1-2 individual sessions administered by a nurse and a physiotherapist. Self-management was emphasized. Effectiveness was expressed in terms of quality of life and forced expiratory volume in one second (FEV1). Doctor visits, days off work, dispensed pharmaceuticals, hospital admissions, travel costs, time costs and educational costs were recorded. The control and intervention groups induced mean total costs of Norwegian Krone (NOK) 16,000 and 10,500 per patient, respectively. A 10-unit improvement in St. George's Respiratory Questionnaire total score and a 5% improvement in FEV1 in the intervention group were associated with a saving of NOK 3,400 and 4,500, respectively, compared to the control group. The number needed to educate (NNE) to make one person symptom free was associated with a saving of NOK 12,200. The results were robust to realistic changes in the assumptions upon which they were based. It could be concluded from this study that patient education in asthmatics in a 12-month follow-up improved patient outcomes and reduced costs.

Patient satisfaction with healthcare in asthmatics and patients with COPD before and after patient education.

Patient satisfaction with general practitioners (GP) and pulmonary outpatient clinics has not been previously compared in patients with asthma and chronic obstructive pulmonary disease (COPD) in addition to the effect of patient education on this satisfaction. We randomly allocated 78 asthmatics and 62 patients with COPD after ordinary outpatient management to a control or an intervention group. Intervention consisted of educational group sessions and individual sessions administered by a trained nurse and physiotherapist. A self-management plan was developed. A patient satisfaction questionnaire was answered at baseline and at the 1-year follow-up. Before randomization, a higher proportion of asthmatics were satisfied with the overall handling of their disease by the outpatient clinic (86%) compared with their GPs (72%, P=0.027, chi2-test). Equal and high proportions of patients with COPD were satisfied with both their GPs (85%) and the outpatient clinic (87%) and in general seemed more satisfied with their GP than asthmatics (P=0.064). At the 1 year follow-up, 100% of the educated patients with COPD reported overall satisfaction with GPs compared with 78% in the control group (P=0.023), but not for asthmatics (75 and 78%, respectively, P=0.581). We conclude that before being given education, asthmatics are more satisfied with the pulmonary outpatient clinic than with GPs, regarding the overall handling of their disease. Patients with COPD seemed more satisfied with GPs than asthmatics. For patients with COPD, patient education seemed to improve overall patient satisfaction with GPs, but this was not true for asthmatics. At baseline, overall satisfaction with the outpatient clinic was so beneficial that we had little chance of detecting any improvement.

Smoking status, disease duration, and educational level in females, are related to asthma school participation.

Limited data is available on those who do not want to attend an asthma school. Two hundred and forty-five asthmatics aged 18-65 yrs with an FEV1 >50% predicted who had been seen at our outpatient asthma clinic within the last 3 yrs were invited to participate in an asthma school. The patients were contacted by phone by a nurse, offered a 2 day asthma school without personal costs. Altogether 78% of those contacted answered positively. In a logistic regression analysis including sex, age, smoking status, educational level, asthma duration and own opinion of the disease, the-adjusted odds ratio (OR) for nonsmokers wanting to participate versus smokers was 4.0 (95% confidence interval (CI): 1.8-8.3). The corresponding figure for patients with a recent asthma attack was 3.4 (95% CI: 1.5-7.6) compared to those without. For every 10 yr duration of disease the OR for wanting to take part in the asthma school increased by 1.6 (95% CI: 1.0-2.3). When analysing males and females separately, highly educated females were less willing to take part, while an opposite tendency was present in males. In conclusion those interested in taking part in an asthma school were characterized by highly motivated nonsmokers with long duration of disease and with a recent asthma attack, and not being highly educated females.

[Do health personnel talk about passive smoking with parents of small children?]. / Snakker helsepersonell med småbarnsforeldre om passiv røyking?

INTRODUCTION: Almost seven out of ten parents who smoke state that they have never received information on passive smoking from health personnel when they bring their children in for routine medical examination. We examined what GPs, doctors and nurses at mother-and-child clinics and midwives reported. MATERIAL AND METHODS: A self-administered questionnaire focusing on practice as regards the matter of passive smoking and children was mailed to a representative sample of 1050 GPs, the senior midwives at Norway's 77 maternity departments, 492 senior public health nurses, and health personnel at 1024 mother-and-child clinics. The response rate varied from 71% (GPs) to 82% (senior midwives). RESULTS: 70% of the personnel at mother-and-child clinics less often than "always" ask about exposure to passive smoking. 60% of the senior midwives report that the department's personnel less than "to a large extent" allocate time to talk with parents about passive smoking. 40% of the GPs and 50% of the paediatricians say that they "never" bring up the matter of passive smoking when they examine small children and do not know whether members of the household smoke or not. The rest of the GPs bring up the matter in 46% of consultations and the rest of the paediatricians in 63% of consultations. When the child has symptoms that can be associated with passive smoking, the GPs discuss the parents' smoking habits in 88% of the consultations and paediatricians in 100% of consultations. INTERPRETATION: Only to a small extent do health personnel use their opportunities of motivating parents to change their smoking habits for the sake of the health of their children. Smoking is only brought up by professionals as a matter routine when the children develop symptoms of exposure to tobacco smoke.

[Smoking cessation practice among Norwegian hospital physicians]. / Norske sykehuslegers praksis ved røykeavvenning.

BACKGROUND: Limited data is available as to what extent Norwegian hospital doctors ask their patients about their smoking habits, and to what extent doctors offer their patients help in smoking cessation. MATERIAL AND METHODS: A random sample of 1,025 hospital doctors was mailed a questionnaire. After 14 days a reminder letter was sent to non-responders; 76% of the doctors responded. RESULTS: Altogether 98% of the doctors stated that they asked their patients with smoking-related disease about their smoking habits. In cases of non-smoking related disease, 73% of the doctors stated that they asked about the smoking habits of their patients (83% of female and 69% of male doctors). If doctors knew that a patient wanted to quit smoking, 25% of them stated that they often recommended nicotine replacement therapy. Less than 7% of the doctors regularly offered smoking cessation courses, handed out self-assistant material, or gave the patients other smoking cessation advice. INTERPRETATION: The study indicates that doctors often ask their patients about their smoking habits, but there is clear potential for improvement as to the smoking cessation advice.

Impact of patient education and self-management on morbidity in asthmatics and patients with chronic obstructive pulmonary disease.

The effect of patient education on morbidity in asthmatics and COPD patients has not previously been investigated in a single study. We randomized 78 asthmatics and 62 COPD patients after ordinary outpatient management. Intervention consisted of educational group sessions and individual sessions administered by a trained nurse and physiotherapist. A self-management plan was developed. The utilization of health resources and absenteeism from work was self-reported monthly. During the 12-month follow-up, approximately two (P= 0.001) and three (P= 0.001) times as many uneducated asthmatics and COPD patients, respectively, visited their general practitioner (GP) compared with educated. The mean reduction in GP consultations for the educated were 73% (P<0.001) and 85% (P<0.0001) for the asthma and COPD group, respectively, compared with uneducated. Fifty percent of uneducated asthmatics reported absenteeism from work compared with 24% of the educated (P = 0.06). The mean reduction in days offwork for the educated was 69% (P = 0.03), compared with uneducated. A positive correlation was observed between St George's Respiratory Questionnaire total score and number of GP visits for both the asthma and COPD group (P < 0.001). We conclude that patient education in asthmatics and COPD patients reduced the need for GP visits and kept a greater proportion of patients independent of their GP. Patient education among asthmatics also reduced the number of days off work and appeared to increase the proportion of patients not reporting absenteeism from work at all. Increasing number of GP visits was correlated with decreased health-related quality of life as measured by the SGRQ for both the asthmatics and the COPD patients.

How does patient education and self-management among asthmatics and patients with chronic obstructive pulmonary disease affect medication?

The effect of patient education on steroid inhaler compliance and rescue medication utilization in patients with asthma or chronic obstructive pulmonary disease (COPD) has not been previously investigated in a single study. We randomized 78 asthmatics and 62 patients with COPD after ordinary outpatient management. Intervention consisted of two 2-h group sessions and 1 to 2 individual sessions by a trained nurse and physiotherapist. A self-management plan was developed. We registered for 12 mo medication dispensed from pharmacies according to the Anatomical Therapeutic Chemical (ATC) classification index. Steroid inhaler compliance (SIC) was defined as (dispensed/prescribed) x 100 and being compliant as SIC > 75%. Among asthmatics 32% and 57% were compliant (p = 0.04) with a median (25th/75th percentiles) SIC of 55% (27/96) and 82% (44/127) (p = 0.08) in the control and intervention groups, respectively. Patient education did not seem to change SIC in the COPD group. Uneducated patients with COPD were dispensed double the amount of short-acting inhaled beta(2)-agonists compared with the educated group (p = 0.03). We conclude that patient education can change medication habits by reducing the amount of short-acting inhaled beta(2)-agonists being dispensed among patients with COPD. Educated asthmatics showed improved steroid inhaler compliance compared with the uneducated patients, whereas this seemed unaffected by education in the COPD group.

Quality of life assessment after patient education in a randomized controlled study on asthma and chronic obstructive pulmonary disease.

The effect of patient education in patients with asthma and Chronic Obstructive Pulmonary Disease (COPD) on health-related quality of life (HRQoL) is not previously investigated using the St. George's Respiratory Questionnaire (SGRQ). We randomly allocated at our out-patient clinic 78 asthmatics and 62 patients with COPD to either a control or an intervention group. Intervention consisted of two 2-h group sessions and one to two individual sessions each by a nurse and a physiotherapist. A self-management plan was developed. Baseline quality of life assessment showed comparable scores independent of treatment groups among asthmatics and patients with COPD, but statistically significantly better scores (p < 0.05) for the educated asthma group after 12 mo compared with the control group. This aligned with the 12-mo SGRQ assessment, which revealed better symptoms, activity, impact, and total scores by 11 (p < 0.02), 15 (p < 0.01), 19 (p < 0.001), and 16 (p < 0.001) units, respectively. Patient education among asthmatics increased the FEV1 by a mean value of 6.1% (SD, 12) compared with the control group (p < 0.05). Education among patients with COPD did not indicate a significant increase in HRQoL as measured by the SGRQ or increased FEV1. We conclude that patient education increased HRQoL and FEV1 among asthmatics, but not among patients with COPD.

[Medication practice and personal knowledge of the disease among patients with obstructive lung disease]. / Medikamentvaner og kunnskap om egen sykdom blant pasienter med obstruktiv lungesykdom.

250 patients with obstructive lung disease who had attended an out-patient clinic were assessed after reporting on individual medication practices and their personal knowledge of the disease. 56% of the patients reported using two types of asthma medicine. The use of three, four, and five or more antasthmatica was reported by 26%, 9% and 5%, respectively. 90% had been prescribed an inhalation corticosteroid. Of these, one in five reported using it only when required, whereas in the age group 18-34 years the corresponding figure was one in three (34%). Regardless of what medication the patients were using, 20% reported that they often forgot to take it, 20% that they stopped taking it when their asthma improved, and 38% that they did not think about what time of the day they took their medicine. These practices of taking medication occurred more frequently in the young than in older patients. Practices did not vary with either a person's sex, duration of disease, or the patient's personal assessment of the seriousness of the disease. Patients with a higher level of education seemed to have greater knowledge of their disease than those with only secondary education, as was also the case with nonsmokers compared to smokers.

Primary hyperparathyroidism or hypercalcaemia of malignancy?

The introduction of two-site immunometric assays measuring intact parathyroid hormone (PTH) and radioimmunoassays measuring PTH-related peptide (PTH-RP) have simplified the evaluation of patients with hypercalcaemia. We present a 63-year-old man with recurrent hypercalcaemia after surgical treatment for primary hyperparathyroidism 3 years previously. PTH measured with a mid-region radioimmunoassay gave normal values, at the same level as during his primary hyperparathyroidism. Intact PTH was, however, clearly suppressed, and he had a highly elevated level of PTH-RP. This suggested that he had humoral hypercalcaemia of malignancy. The patient died after 2 months, and at autopsy an adenocarcinoma of the pancreas with no skeletal metastases was found.

[Hypothyroid cardiomyopathy--an underdiagnosed cause of heart failure]. / Hypotyreot kardiomyopati--en underdiagnostisert årsak til hjertesvikt.

20 patients with hypothyroid cardiomyopathy were evaluated by M-mode echocardiography. The mean interventricular septum (IVSd) thickness was 1.94 cm before treatment and was reduced to 1.21 cm after 4-6 months of thyroxin therapy. The mean left ventricular posterior wall (LVPWd) thickness was 1.14 cm before and 1.05 cm after treatment. The IVS/LVPW ratio decreased from 1.7 to 1.15 within 4-6 months. Pericardial effusion was demonstrated in 15 of the patients, but disappeared during thyroxin therapy. The study confirms the importance of examining for hypothyreoidism in the case of patients with symptoms of heart failure of unknown cause, and of patients with echocardiographic evidence of asymmetric septal hypertrophy (ASH) and idiopathic hypertrophic subaortic stenosis (IHSS).