Multivalvular destruction as the primary presentation of aggressive infective endocarditis with subaortic valve membrane.

Multivalvular destruction may be a clinical manifestation of infective endocarditis (IE), which is a devastating infection of the heart either alone or superimposed with congenital subaortic membrane as in this case report. Here, we report a case of multivavular destruction with severe vegetation presented as a manifestation of infective endocarditis (IE) in a neglected case of 18-year-old male with previous rheumatic heart disease. Transesophageal echocardiography is an important imaging modality for diagnosis of superimposed aortic and heart lesions. Early necessary investigation and correct diagnosis is mandatory to prevent bad complications.

Gender and side distribution of urinary calculi using ultrasound imaging.

INTRODUCTION: Urinary calculi constitute a significant medical problem worldwide. Due to lack of previous studies on gender and side distribution of urinary calculi, the current study was conducted. PATIENTS AND METHODS: This retrospective study involved 590 urinary calculi from the electronic reports of 266 patients. Gender and side distribution were compared using Chi-square test. Relationship between gender and side of urinary calculi was analyzed using cross tabulation test. RESULTS: This study involved 590 urinary calculi reported in 266 patients. Among 590 calculi; 565 (95.8%) were in adults, and 25 (4.2%) were in children. Urinary calculi were in male in 397 (67.3%) and in female in 193 (32.7%). Calculi were 304 (51.5%) in right side, and 286 (48.5%) in left side. Exactly 507 (85.9%) of calculi were in the kidneys, and 83 (14.1%) in the ureters. No significant relationship between gender and side of the calculi (P = 0.238), (Odds ratio 0.869, 95% Confidence interval 0.615-1.226). CONCLUSION: Urinary calculi affect male more than female and adults more than children. No significant relationship between calculi and right or left side of the body.

Histopathological analysis of sinonasal lesions associated with chronic rhinosinusitis and comparison with computed tomography diagnoses.

BACKGROUND &OBJECTIVE: Chronic rhino sinusitis (CRS) is an inflammatory condition of the paranasal sinuses and the nasal passage lasting more than three months either with or without sinonasal polyps. This study aimed to report the common sinonasal lesions associated with CRS according to the histopathology results, to compare between clinical and histopathological diagnoses, and to compare between radiological and histopathological diagnoses of the sinonasal lesions. METHODS: A retrospective study of the electronic records of 82 patients diagnosed with CRS with nasal polyps. All patients underwent endoscopic sinus surgery and histopathological examination of surgical biopsies. The collected data were analyzed using SPSS program. Coparison between clinical and histopathological diagnoses was done. This study was conducted at Alsafwa Consultative Medical center (ACMC) in Almukalla city, Hadhramout province in Republic of Yemen. RESULTS: Out of 82 patients, the ages ranged from 4 to 90 years (mean: 34.48±17.74 years), and 54.88% were females. Inflammatory polyps were the most common lesion (31.4%), then allergic polyps (30.5%). Nasopharyngeal carcinoma (NPC) was reported in 9.8% of the lesions and all were unilateral. The results revealed strong compatibility between clinical and histopathological diagnoses (p<0.001, kappa= 0.215), and significant compatibility between radiological and histopathology diagnoses (p=0.007). CONCLUSION: Inflammatory and allergic polyps are the most common benign bilateral lesions associated with chronic rhinosinusitis, which can be correctly diagnosed clinically in most cases. Unilateral nasal polyps have high rates of malignancies and should be check carefully by endoscopy and histopathology. Computed tomography has some pitfalls in diagnosing of fungal sinusitis.

Doppler sonographic assessment of carotid arteries in Sudanese stroke patients.

BACKGROUND: Hypertension, diabetes, and smoking were considered to be associated with several public health problems. OBJECTIVE: the study aims to explore the hemodynamic of carotid arteries in association with hypertension, diabetes, and smoking in Sudanese stroke patients. MATERIALS AND METHODS: In a quantitative descriptive study, fifty patients with stroke were scanned by B-mode and Doppler sonography. Carotid arteries were investigated with a 7-MHz linear transducer by a standard carotid sonography protocol. RESULTS: The average Doppler resistive index (RI) was 0.71 ± 0.084 and intima-media thickness was 1.39 ± 0.78 mm. The end diastolic velocities (EDVs) and peak systolic velocities (PSVs) of common carotid arteries were significantly changed in smokers and hypertensive (P < 0.05). The elevation of RI in right and left CCAs were significantly correlated with smokers (P = 0.017 and 0.010 respectively). Hemorrhagic stroke was most prevalent in hypertensive rather than diabetic and smokers. The carotid hemodynamics changed significantly in hypertensive and smokers more than diabetics. CONCLUSION: EDV and PSV were significantly correlated with hypertension and tobacco smoking rather than diabetes. Hypertension, diabetes, and smoking have an association with stroke and hand significant effect on carotid artery hemodynamic and atherosclerotic disease. The Doppler RIs were significantly correlated with smokers. Patients with risk factors of stroke should be scanned with Doppler sonography as early as possible.