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1.
J Pediatr Orthop ; 2024 Sep 11.
Artigo em Inglês | MEDLINE | ID: mdl-39256907

RESUMO

INTRODUCTION: Children with cerebral palsy (CP) have high rates of foot deformity. Accurate assessment of foot morphology is crucial for therapeutic planning and outcome evaluation. This study aims to evaluate the reliability of a novel photo-based Modified Foot Posture Index (MFPI) in the evaluation of foot deformity in children with CP. METHODS: Thirteen orthopaedic surgeons with neuromuscular clinical focus from 12 institutions evaluated standardized standing foot photographs of 20 children with CP, scoring foot morphology using the MFPI. Raters scored the standardized photographs based on five standard parameters. Two parameters assessed the hindfoot: curvature above and below the malleoli and calcaneal inversion/eversion. Three parameters assessed the midfoot and forefoot: talonavicular congruence, medial arch height, and forefoot abduction/adduction. Summary MFPI scores range from -10 to +10, where positive numbers connote planovalgus, whereas negative numbers connote a tendency toward cavovarus. Intra- and interrater reliability were calculated using a 2-way mixed model of the intraclass correlation coefficient (ICC) set to absolute agreement. RESULTS: Feet spanned the spectrum of potential pathology assessable by the MFPI, including no deformity, mild, moderate, and severe planovalgus or cavovarus deformities. All scored variables showed high intrarater reliability with ICCs from 0.891 to 1. ICCs for interrater reliability ranged from 0.965 to 0.984. Hindfoot total score had an ICC of 0.979, with a 95% CI, 0.968-0.988 (P<0.001). The forefoot total score had an ICC of 0.984 (95% CI, 0.976-0.991, P<0.001). Mean total score by the MFPI was 3.67 with an ICC of 0.982 (95% CI, 0.972-0.990, P<0.001). CONCLUSIONS: The photo-based MFPI demonstrates high intra- and interrater reliability in assessing foot deformities in children with CP. Its noninvasive nature and ease of use make it a promising tool for both clinical and research settings. MFPI should be considered as part of standard outcomes scores in studies regarding the treatment of CP-associated foot deformities. LEVEL OF EVIDENCE: Level V.

2.
J Pediatr Orthop ; 44(10): e945-e950, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-39099072

RESUMO

BACKGROUND: Osteogenesis imperfecta (OI) is a genetic defect in collagen type I, phenotypically characterized by bony fragility and a propensity to high rates of childhood fracture. Fragility fractures in patients with OI have been reported with routine hospital care. In addition, there is a nonzero rate of iatrogenic fracture during orthopaedic surgery directly related to the technical steps of the procedure itself. The rate of this latter has never been explicitly investigated. METHODS: A review of all patients at a single OI referral center was conducted, including all patients with a diagnosis of OI seen between 2013 and 2023, inclusive. All patients who underwent orthopaedic surgery of any kind were reviewed, and clinical and radiographic details of all procedures were extracted. Among the details examined were the OI subtype, surgery details, any implants used, intraoperative and hospital stay complications, modified Clavien-Dindo classification of complications, and ultimate outcome. RESULTS: Eleven of 60 patients experienced an unplanned, iatrogenic intraoperative fracture during orthopaedic surgery (11/60 = 18.3%). This comprised 15 fractures among 356 total orthopaedic surgical episodes (15/356 = 4.2%). All but one fracture occurred on the operative long bone segment, all were a direct result of surgical steps, and 11 of 15 fractures occurred in the femur. Most fractures were secondary to the removal, insertion, or exchange of intramedullary implants in the lower extremity (11 of 15 fractures), most often the femur. Thirteen of 15 injuries were classified as modified Clavien-Dindo II or III, requiring modification of postop rehabilitation, additional treatments, or surgical intervention (87%). Overall, iatrogenic fracture was the most common intraoperative complication experienced in the cohort. CONCLUSIONS: Iatrogenic fracture during orthopaedic surgery for patients with OI is not uncommon. A sizeable minority of patients with OI undergoing orthopaedic surgery will experience unplanned fractures, most commonly in the femur, and care is altered in most instances. The risk of intraoperative fracture can be discussed with families of children with OI as part of informed consent and shared decision-making. LEVEL OF EVIDENCE: Level IV-retrospective cohort series.


Assuntos
Doença Iatrogênica , Complicações Intraoperatórias , Osteogênese Imperfeita , Humanos , Osteogênese Imperfeita/complicações , Osteogênese Imperfeita/cirurgia , Feminino , Criança , Masculino , Pré-Escolar , Estudos Retrospectivos , Adolescente , Complicações Intraoperatórias/etiologia , Fraturas Ósseas/cirurgia , Fraturas Ósseas/etiologia , Procedimentos Ortopédicos/efeitos adversos , Procedimentos Ortopédicos/métodos , Lactente
3.
J Child Orthop ; 18(2): 200-207, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38567040

RESUMO

Purpose: Congenital femoral deficiency is characterized by limb length discrepancy and genu valgum. Lengthening of the femur along its anatomic axis increases valgus alignment by medial knee translation. Pairing limb lengthening with simultaneous medial distal femoral hemiepiphysiodesis can simultaneously correct two limb deformities. Methods: All skeletally immature patients with congenital femoral deficiency who underwent antegrade femoral lengthening and concomitant guided growth over a 4-year period were reviewed. Length and alignment data were quantified during lengthening, consolidation, and for 1 year after guided growth implants were removed or the patient reached skeletal maturity. Digital simulation was performed for all lengthenings to assess the mechanical alignment that would have been achieved had lengthening been performed without medial distal femoral hemiepiphysiodesis. Results: Nine patients (five males, four females, mean age = 12.3 ± 1.9 years) underwent 10 antegrade intramedullary femoral lengthenings with simultaneous medial distal femoral hemiepiphysiodesis. All had improvement in valgus alignment (average improvement in mechanical axis deviation was 18 ± 11 mm, average change in limb alignment was 6 ± 5°). In simulated lengthenings without guided growth, all limbs would have experienced increased lateral mechanical axis deviation of 5 ± 3 mm. The hemiepiphysiodesis implant and lengthening device were explanted simultaneously in 7 of 10 lengthenings. Conclusion: Simultaneous medial distal femoral hemiepiphysiodesis with antegrade femoral lengthening for ongenital femoral deficiency can minimize the number of surgical episodes for the skeletally immature patient. The lengthening device and guided growth construct can be removed simultaneously in a majority of cases, saving children one or two additional surgical treatments.

4.
PLoS One ; 19(4): e0301230, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38593122

RESUMO

BACKGROUND: Instrumented gait analysis (IGA) has been around for a long time but has never been shown to be useful for improving patient outcomes. In this study we demonstrate the potential utility of IGA by showing that machine learning models are better able to estimate treatment outcomes when they include both IGA and clinical (CLI) features compared to when they include CLI features alone. DESIGN: We carried out a retrospective analysis of data from ambulatory children diagnosed with cerebral palsy who were seen at least twice at our gait analysis center. Individuals underwent a variety of treatments (including no treatment) between sequential gait analyses. We fit Bayesian Additive Regression Tree (BART) models that estimated outcomes for mean stance foot progression to demonstrate the approach. We built two models: one using CLI features only, and one using CLI and IGA features. We then compared the models' performance in detail. We performed similar, but less detailed, analyses for a number of other outcomes. All results were based on independent test data from a 70%/30% training/testing split. RESULTS: The IGA model was more accurate than the CLI model for mean stance-phase foot progression outcomes (RMSEIGA = 11∘, RMSECLI = 13∘) and explained more than 1.5 × as much of the variance (R2IGA = .45, R2CLI = .28). The IGA model outperformed the CLI model for every level of treatment complexity, as measured by number of simultaneous surgeries. The IGA model also exhibited superior performance for estimating outcomes of mean stance-phase knee flexion, mean stance-phase ankle dorsiflexion, maximum swing-phase knee flexion, gait deviation index (GDI), and dimensionless speed. INTERPRETATION: The results show that IGA has the potential to be useful in the treatment planning process for ambulatory children diagnosed with cerebral palsy. We propose that the results of machine learning outcome estimators-including estimates of uncertainty-become the primary IGA tool utilized in the clinical process, complementing the standard medical practice of conducting a through patient history and physical exam, eliciting patient goals, reviewing relevant imaging data, and so on.


Assuntos
Paralisia Cerebral , Transtornos Neurológicos da Marcha , Criança , Humanos , Análise da Marcha , Estudos Retrospectivos , Paralisia Cerebral/cirurgia , Teorema de Bayes , Marcha , Amplitude de Movimento Articular , Imunoglobulina A , Fenômenos Biomecânicos , Transtornos Neurológicos da Marcha/terapia
5.
JBJS Case Connect ; 14(1)2024 01 01.
Artigo em Inglês | MEDLINE | ID: mdl-38306444

RESUMO

CASE: A 19-year-old female athlete experienced calf pain during sport. A complete Achilles tendon rupture was diagnosed 4 weeks after injury. Ultrasound revealed discontinuity of the Achilles tendon with 2.0 cm of diastasis, persisting in plantarflexion. Plantarflexion immobilization was initiated, and progressive dorsiflexion was used until 10 weeks from injury. At 1 year from injury, ankle magnetic resonance imaging revealed a contiguous tendon, the patient was pain-free, and had returned to high-level athletics with equivalent sport performance relative to her preoperative status. CONCLUSION: Certain Achilles tendon ruptures in young people may be treated nonoperatively with good clinical outcomes, even if diagnosis and immobilization are delayed and tendon diastasis persists in maximum plantarflexion.


Assuntos
Tendão do Calcâneo , Traumatismos do Tornozelo , Traumatismos dos Tendões , Feminino , Adolescente , Humanos , Adulto Jovem , Adulto , Tendão do Calcâneo/cirurgia , Diagnóstico Tardio , Ruptura/terapia , Ruptura/cirurgia , Traumatismos dos Tendões/terapia , Traumatismos dos Tendões/cirurgia , Atletas
6.
J Am Acad Orthop Surg ; 32(9): e413-e424, 2024 May 01.
Artigo em Inglês | MEDLINE | ID: mdl-38091584

RESUMO

Genu recurvatum-valgus arises from the proximal tibia and poses challenges in its treatment. The etiology of the combined deformities can include physeal trauma (often unrecognized), iatrogenic injury, infection, tumor, Osgood-Schlatter syndrome, skeletal dysplasia, and ligamentous laxity. Both osseous and ligamentous contributions must be recognized for successful treatment. A graphical planning method identifies the true (oblique) plane of deformity. Surgical treatment options include epiphysiodesis to prevent progressive deformity, guided growth, opening-wedge proximal tibial osteotomy, and gradual correction with concomitant limb lengthening using external fixation or motorized internal lengthening. Opening-wedge proximal tibial osteotomy conducted along the true deformity plane is a reliable surgical method for lesser-magnitude deformities. Gradual correction using circular external fixation is considered when the magnitude of correction is greater than 25º or when limb shortening and/or multiplanar deformity is present. After successful surgical management, patients can expect to achieve correction of knee hyperextension, posterior tibial slope, and mechanical axis. Restoration of these parameters re-establishes physiologic loading of the knee. This review illustrates the clinical and radiographic assessment of the deformity, relevant anatomy, and five surgical techniques for the genu recurvatum-valgus deformity of the proximal tibia.

7.
Strategies Trauma Limb Reconstr ; 18(2): 106-110, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37942433

RESUMO

Aim: This study reviews the re-use of implanted motorised intramedullary lengthening nails previously used for limb lengthening. Materials and methods: A retrospective review was performed on the re-use of motorised intramedullary lengthening nails. All patients had a magnetically controlled intramedullary lengthening nail in the femur, tibia, or humerus previously utilised for either lengthening or compression. Patients were included if the magnetically controlled intramedullary lengthening nail underwent attempted re-use either in the same lengthening episode or in a temporally separate lengthening treatment requiring another corticotomy. Results: Ten patients with 12 lengthening episodes were analysed including five tibial, five femoral and two humeral segments. Overall, seven of 12 nails (58%) were successfully re-deployed without the need for nail exchange. Two of three nails were successfully retracted and re-used for continued distraction in the same lengthening treatment. Five of nine nails (56%) were successfully reactivated in a subsequent, later lengthening episode. Conclusion: Re-use of a magnetically controlled limb lengthening nail is an off-label technique that may be considered for patients requiring ongoing or later lengthening of the femur, tibia or humerus. Regardless of whether the nail is used in the same lengthening episode or separate lengthening episode, surgeons should be prepared for exchange to a new implant. Clinical significance: Re-use of a magnetically controlled intramedullary lengthening nail will reduce surgical trauma and save implant cost in limb lengthening treatment but may only be possible in half of attempted cases. How to cite this article: Georgiadis AG, Nahm NJ, Dahl MT. Re-use of Motorised Intramedullary Limb Lengthening Nails. Strategies Trauma Limb Reconstr 2023;18(2):106-110.

8.
PLoS One ; 17(12): e0270731, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36576918

RESUMO

Walking is an important skill with positive impacts on health, function, and well-being. Many disorders impair walking and its positive impacts through a variety of complex and interrelated mechanisms. Any attempt to understand walking impairments, or the effects of interventions intended to treat these impairments, must respect this complexity. Therefore, our main objectives in conducting this study were to (1) propose a comprehensive model for quantifying the causes and consequences of walking impairments and (2) demonstrate the potential utility of the model for supporting clinical care and addressing basic scientific questions related to walking. To achieve these goals, we introduced a model, described by a directed acyclic graph, consisting of 10 nodes and 23 primary causal paths. We gave detailed descriptions of each node and path based on domain knowledge. We then demonstrated the model's utility using a large sample of gait data (N = 9504) acquired as part of routine care at a regional referral center. We analyzed five relevant examples that involved many of the model's nodes and paths. We computed causal effect magnitudes as Shapley values and displayed the overall importance of variables (mean absolute Shapley value), the variation of Shapley values with respect to underlying variables, and Shapley values for individual observations (case studies). We showed that the model was plausible, captured some well-known cause-effect relationships, provided new insights into others, and generated novel hypotheses requiring further testing through simulation or experiment. To aid in transparency, reproducibility, and future enhancements we have included an extensively commented Rmarkdown file and a deidentified data set.


Assuntos
Marcha , Caminhada , Reprodutibilidade dos Testes , Simulação por Computador , Nível de Saúde
9.
J Am Acad Orthop Surg ; 30(23): e1483-e1494, 2022 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-36137096

RESUMO

Park-Harris lines are radiographically apparent linear opacities that occur in a metaphyseal bone in proximity to a physis. Lines correspond to a temporary interruption of the normally ossifying physis with a sclerotic line corresponding to transversely oriented trabeculae. They were first appreciated in the long bones of diabetic children and have since been described in various metabolic, endocrinologic, infectious, neoplastic, and posttraumatic conditions as well as in response to systemic medications. Park-Harris lines are clinically useful in demarcating notable events in whole-body or individual bone development, in tracking longitudinal growth, or in assessing physeal arrest and responses to its treatment. There remains controversy about whether these lines are pathologic or a component of physiologic development and whether they constitute true "growth arrest" or rather "growth recovery." In this review, the history, pathophysiology, imaging, and clinical use of Park-Harris lines as well as an anthropological perspective on their utility for studying illness, nutrition, and historical living conditions over time are discussed.


Assuntos
Desenvolvimento Ósseo , Lâmina de Crescimento , Humanos , Criança , Osso e Ossos
10.
J Pediatr Orthop ; 42(10): e987-e993, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36084628

RESUMO

BACKGROUND: Limb lengthening by distraction osteogenesis can be performed with motorized internal devices, but intramedullary implants risk avascular necrosis of the femoral head in young children. A method of internal limb lengthening using a motorized expandable plate has been developed and preliminary results are presented. METHODS: Seven skeletally immature patients (ages 2.7 to 9.7 y) with congenital femoral deficiencies underwent femoral lengthening with the use of a magnetic expandable plate. Surgical details, lengthening parameters, Limb Lengthening and Reconstruction Society-Angular deformity, Infection, Motion index, and complications were reviewed and classified according to the modified Clavien-Dindo system. RESULTS: An average lengthening was 4.1 cm (range, 3.3 to 4.4 cm) comprising 18% of initial femoral segment length (range, 14% to 21%). The average lengthening phase was 50.2 days (range, 40 to 57 d) and weight-bearing was initiated at an average of 13 weeks from surgery (range, 8 to 18 wk). Limb deformities and length discrepancies were of moderate complexity, with an Limb Lengthening and Reconstruction Society-Angular deformity, Infection, Motion score of 6.57 (range, 6 to 7). Complication rates were comparable to previously reported methods of femoral lengthening. One patient underwent reoperation for patellar instability and 1 patient experienced radiographic hip subluxation which was observed. Small magnitude varus was observed in regenerate in 3 of 7 cases, none requiring treatment. Preoperative planning consisted of careful localization of the corticotomy site, acute deformity correction at the lengthening site in 3 cases, and implant orientation. CONCLUSIONS: Limb lengthening with motorized internal plates is feasible for young children with congenital femoral deficiency for whom intramedullary lengthening is unsafe or if external fixation is to be avoided. However, the fundamental principles of distraction osteogenesis and risks of lengthening for congenital discrepancies remain unchanged. Specific considerations herein include: careful planning of implant length and positioning, adjacent joint protection with adjunctive means, and mitigating deformity of the regenerate during distraction. LEVEL OF EVIDENCE: Level IV, retrospective case series.


Assuntos
Alongamento Ósseo , Instabilidade Articular , Osteogênese por Distração , Articulação Patelofemoral , Alongamento Ósseo/métodos , Pinos Ortopédicos , Criança , Pré-Escolar , Fêmur/anormalidades , Fêmur/cirurgia , Humanos , Desigualdade de Membros Inferiores/cirurgia , Osteogênese por Distração/métodos , Estudos Retrospectivos , Resultado do Tratamento
11.
Sci Rep ; 12(1): 7818, 2022 05 12.
Artigo em Inglês | MEDLINE | ID: mdl-35551496

RESUMO

Orthopedic and neurological impairments (e.g., muscle contractures, spasticity) are often treated in children and young adults with cerebral palsy (CP). Due to challenges arising from combinatorics, research funding priorities, and medical practicalities, and despite extensive study, the evidence base is weak. Our goal was to estimate the short-term effectiveness of 13 common orthopedic and neurological treatments at four different levels of outcome in children and young adults diagnosed with CP. The outcome levels considered were body structures, specific gait kinematic deviations, overall gait kinematic deviations, and functional mobility. We used three well-establish causal inference approaches (direct matching, virtual twins, and Bayesian causal forests) and a large clinical gait analysis database to estimate the average treatment effect on the treated (ATT). We then examined the effectiveness across treatments, methods, and outcome levels. The dataset consisted of 2851 limbs from 933 individuals (some individuals underwent multiple treatment episodes). Current treatments have medium effects on body structures, but modest to minimal effects on gait and functional mobility. The median ATT of 13 common treatments in children and young adults with CP, measured as Cohen's D, bordered on medium at the body structures level (median [IQR] = 0.42 [0.05, 0.60]) and became smaller as we moved along the causal chain through specific kinematic deviations (0.21 [0.01, 0.33]), overall kinematic deviations (0.09 [0.03, 0.19]), and functional mobility (-0.01 [-0.06, 0.13]). Further work is needed to understand the source of heterogeneous treatment effects, which are large in this patient population. Replication or refutation of these findings by other centers will be valuable to establish the generalizability of these results and for benchmarking of best practices.


Assuntos
Paralisia Cerebral , Teorema de Bayes , Paralisia Cerebral/terapia , Criança , Marcha , Análise da Marcha , Humanos , Aprendizado de Máquina , Adulto Jovem
12.
JBJS Case Connect ; 12(1)2022 03 03.
Artigo em Inglês | MEDLINE | ID: mdl-35239520

RESUMO

CASES: This case report describes 3 pediatric patients presenting with acute calf or knee pain, calf swelling, and a ruptured popliteal cyst diagnosed by magnetic resonance imaging. Lyme disease was serologically confirmed in each case. In all instances, treatment was delayed because of atypical presentation. All patients responded favorably after antibiotic therapy. CONCLUSION: The differential diagnosis of Lyme disease should be considered in the context of children presenting with atraumatic unilateral calf pain and a ruptured popliteal cyst. Otherwise, this unusual presentation could delay diagnosis or result in unnecessary surgical intervention, particularly in pediatric patients.


Assuntos
Cistos , Doença de Lyme , Cisto Popliteal , Criança , Cistos/complicações , Cistos/diagnóstico por imagem , Humanos , Joelho , Articulação do Joelho/patologia , Doença de Lyme/complicações , Doença de Lyme/diagnóstico , Doença de Lyme/tratamento farmacológico , Cisto Popliteal/diagnóstico por imagem , Cisto Popliteal/etiologia
14.
Dev Med Child Neurol ; 64(3): 379-386, 2022 03.
Artigo em Inglês | MEDLINE | ID: mdl-34534360

RESUMO

AIM: To expand upon previous validation of the Gait Outcomes Assessment List (GOAL) questionnaire in individuals with cerebral palsy (CP), to rank items by importance, and to summarize written-in (free text) goals. METHOD: For this cross-sectional study, the parent-version 5.0 of the GOAL was completed by 310 consecutive caregivers of 310 individuals aged 3 to 25 years with CP (189 males, 121 females; mean [SD] age: 10y [4y 2mo]; Gross Motor Function Classification System [GMFCS] levels I-IV) concurrent with a gait analysis. Distribution properties and validity were quantified using questionnaires, kinematics, and oxygen consumption. Items classified as at least 'difficult' to perform and 'very important' to improve were considered caregiver priorities and rank ordered. Free text goals were categorized. Results were summarized for everyone and by GMFCS level. RESULTS: Most scores were normally distributed. Validity was acceptable, with concurrent greater than construct validity. Among all 310 caregivers, fatigue was the highest priority, followed by gait pattern and appearance items. The rank of priorities varied by GMFCS level. Common free text goals included toileting independently as well as improved fine motor and ball sport skills. INTERPRETATION: The GOAL is a valid tool that can help prioritize goals across GMFCS levels I to IV. Identifying the top goals may improve shared decision-making and prioritize research for this sample.


Assuntos
Atividades Cotidianas , Cuidadores , Paralisia Cerebral/diagnóstico , Transtornos Neurológicos da Marcha/diagnóstico , Índice de Gravidade de Doença , Adolescente , Adulto , Paralisia Cerebral/complicações , Paralisia Cerebral/fisiopatologia , Criança , Pré-Escolar , Estudos Transversais , Exercício Físico/fisiologia , Fadiga/diagnóstico , Fadiga/etiologia , Fadiga/fisiopatologia , Feminino , Transtornos Neurológicos da Marcha/etiologia , Transtornos Neurológicos da Marcha/fisiopatologia , Humanos , Masculino , Dor/diagnóstico , Dor/etiologia , Dor/fisiopatologia , Medidas de Resultados Relatados pelo Paciente , Reprodutibilidade dos Testes , Estudos Retrospectivos , Adulto Jovem
16.
J Pediatr Orthop ; 41(3): 182-189, 2021 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-33323879

RESUMO

BACKGROUND: There are reports of spinal cord injury (SCI) occurring after lower extremity (LE) surgery in children with mucopolysaccharidoses (MPS). Intraoperative neurological monitoring (IONM) has been adopted in some centers to assess real-time spinal cord function during these procedures. The aim of this investigation was to review 3 specialty centers' experiences with MPS patients undergoing LE surgery. We report how IONM affected care and the details of spinal cord injuries in these patients. METHODS: All pediatric MPS patients who underwent LE surgery between 2001 and 2018 were reviewed at 3 children's orthopaedic specialty centers. Demographic and surgical details were reviewed. Estimated blood loss (EBL), surgical time, positioning, use of IONM, and changes in management as a result of IONM were recorded. Details of any spinal cord injuries were examined in detail. RESULTS: During the study period, 92 patients with MPS underwent 252 LE surgeries. IONM was used in 83 of 252 (32.9%) surgeries, and intraoperative care was altered in 17 of 83 (20.5%) cases, including serial repositioning (n=7), aggressive blood pressure management (n=6), and abortion of procedures (n=8). IONM was utilized in cases with larger EBL (279 vs. 130 mL) and longer operative time (274 vs. 175 min) compared with procedures without IONM. Three patients without IONM sustained complete thoracic SCI postoperatively, all from cord infarction in the upper thoracic region. These 3 cases were characterized by long surgical time (328±41 min) and substantial EBL (533±416 mL or 30.5% of total blood volume; range, 11% to 50%). No LE surgeries accompanied by IONM experienced SCI. CONCLUSIONS: Patients with MPS undergoing LE orthopaedic surgery may be at risk for SCI, particularly if the procedures are long or are expected to have large EBL. One hypothesis for the etiology of SCI in this setting is hypoperfusion of the upper thoracic spinal cord due to prolonged intraoperative or postoperative hypotension. IONM during these procedures may mitigate the risk of SCI by identifying real-time changes in spinal cord function during surgery, inciting a change in the surgical plan. LEVEL OF EVIDENCE: Level III-retrospective comparative series.


Assuntos
Monitorização Neurofisiológica Intraoperatória/estatística & dados numéricos , Extremidade Inferior/cirurgia , Mucopolissacaridoses/cirurgia , Procedimentos Ortopédicos/efeitos adversos , Traumatismos da Medula Espinal/etiologia , Criança , Feminino , Humanos , Masculino , Procedimentos Ortopédicos/estatística & dados numéricos , Estudos Retrospectivos , Traumatismos do Sistema Nervoso
17.
J Bone Joint Surg Am ; 102(23): 2077-2086, 2020 Dec 02.
Artigo em Inglês | MEDLINE | ID: mdl-33093298

RESUMO

BACKGROUND: Congenital pseudarthrosis of the tibia is a rare and challenging pediatric condition. The pre-fracture state, called congenital tibial dysplasia or anterolateral bowing of the tibia, presents a high fracture risk due to underlying bowing and dysplasia. After fracture, there is a substantial risk of nonunion. Any union achieved may be complicated by refracture, deformity, leg-length discrepancy, stiffness, pain, and dysfunction. We present the results of using distal tibial growth modulation to improve tibial alignment and to decrease fracture risk in this condition. To our knowledge, this is the first report of isolated distal tibial growth modulation as the primary surgical treatment for this condition. METHODS: This is a retrospective study of 10 patients with congenital tibial dysplasia who presented prior to pseudarthrosis and underwent distal tibial growth modulation as a primary treatment. The medical records and radiographs were reviewed for age at the times of diagnosis and treatment, fracture, secondary procedures, complications, residual deformity, cystic changes, and leg-length discrepancy. RESULTS: Ten patients had a mean follow-up (and standard deviation) of 5.1 ± 1.9 years. No patient sustained a tibial fracture, and no patient developed a tibial pseudarthrosis after guided growth was initiated. The mean age at the initiation of growth modulation was 2.6 ± 1.3 years. Six patients required a plate exchange. The mean residual tibial diaphyseal angular deformity at the most recent follow-up was 4.3° ± 3.2° of varus and 8.4° ± 5.8° in the sagittal plane. Only 1 patient had a clinically important leg-length discrepancy, with the affected leg being longer. CONCLUSIONS: In this series of 10 patients with congenital tibial dysplasia, distal tibial growth modulation delayed or possibly prevented fracture, decreased tibial malalignment, improved radiographic appearance of bone quality, and preserved leg length. No patient developed tibial fracture or pseudarthrosis after the initiation of guided growth treatment. Although early results are promising, follow-up to maturity is required to define the exact role of this simple outpatient procedure in congenital tibial dysplasia. LEVEL OF EVIDENCE: Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.


Assuntos
Pseudoartrose/congênito , Fraturas da Tíbia/prevenção & controle , Placas Ósseas , Parafusos Ósseos , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Masculino , Pseudoartrose/cirurgia , Estudos Retrospectivos , Tíbia/anormalidades , Tíbia/crescimento & desenvolvimento , Tíbia/cirurgia
18.
JBJS Case Connect ; 10(3): e20.00083, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32910578

RESUMO

CASE: A 10-year-old boy experienced a pathologic diaphyseal femur fracture through a large cyst encompassing 40% of femoral length. At age 5, he had had a traumatic ipsilateral diaphyseal femur fracture, treated with flexible nailing. Biopsy at age 10 revealed a simple bone cyst with components of aneurysmal bone cyst. Curettage, antegrade nailing, and allograft resulted in successful osseous healing. CONCLUSION: Post-traumatic cysts of long bones are rare and have not been reported to cause pathologic fracture in children. This case highlights that close scrutiny of follow-up radiographs of long bone fractures may identify clinically important post-traumatic cysts.


Assuntos
Cistos Ósseos Aneurismáticos/complicações , Fraturas do Fêmur/etiologia , Fêmur/patologia , Fraturas Espontâneas/etiologia , Complicações Pós-Operatórias/etiologia , Cistos Ósseos Aneurismáticos/patologia , Cistos Ósseos Aneurismáticos/cirurgia , Criança , Pré-Escolar , Fraturas do Fêmur/cirurgia , Fêmur/cirurgia , Fraturas Espontâneas/cirurgia , Humanos , Masculino , Complicações Pós-Operatórias/patologia , Complicações Pós-Operatórias/cirurgia
19.
J Pediatr Orthop ; 40(10): e978-e983, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32604346

RESUMO

BACKGROUND: Limb lengthening by distraction osteogenesis is now achievable via motorized intramedullary devices, mitigating many complications of lengthening by external fixation. In young patients, antegrade intramedullary nailing of the femur risks avascular necrosis of the femoral head. A method of extramedullary placement of a motorized expandable intramedullary nail has been employed by the senior author to safely achieve femoral lengthening without the use of an external fixator in young patients. METHODS: Eleven skeletally immature patients with lower limb length discrepancy were reviewed who underwent extramedullary placement of a magnetic, expandable intramedullary nail for lengthening of the femur. Surgical details, lengthening parameters, and complications were reviewed and classified according to the modified Clavien-Dindo Classification. RESULTS: Average lengthening was 32.3 mm (range: 27 to 40 mm) comprising an average 14.8% of femoral segment length. The average lengthening duration was 6.3 weeks, and average full weight-bearing began at 12.6 weeks. All but 1 patient underwent early removal of the device at an average of 4.5 months, and 5 had immediate plating of the femur. Complications rates were comparable to other methods of femoral lengthening, including varus or procurvatum through the regenerate, and unplanned reoperation in 3 of 11 cases. Preoperative considerations included careful planning of implant length due to short femoral segments and protection of the knee joint from contracture or iatrogenic instability. CONCLUSIONS: Extramedullary placement of a magnetic expandable intramedullary lengthening nail can achieve lengthening of the femur without the use of external fixation. Considerations with this technique include careful planning of implant length relative to trochanteric-physeal distance, protection against knee subluxation during lengthening, and mitigating deformity of the regenerate. Off-label, extramedullary use of these devices can be considered to decrease the burdens of external fixation in young children. The technique begs the advent of future all-internal technology specifically designed for safe limb lengthening in this age group. LEVEL OF EVIDENCE: Level IV-retrospective case series.


Assuntos
Pinos Ortopédicos , Fêmur/cirurgia , Desigualdade de Membros Inferiores/cirurgia , Osteogênese por Distração/métodos , Criança , Pré-Escolar , Feminino , Fixação Intramedular de Fraturas/efeitos adversos , Fixação Intramedular de Fraturas/instrumentação , Humanos , Imãs , Masculino , Osteogênese por Distração/efeitos adversos , Osteogênese por Distração/instrumentação , Complicações Pós-Operatórias/etiologia , Reoperação , Estudos Retrospectivos , Resultado do Tratamento
20.
J Am Acad Orthop Surg ; 28(18): e803-e809, 2020 Sep 15.
Artigo em Inglês | MEDLINE | ID: mdl-32520902

RESUMO

Intramedullary limb lengthening (LL) is now achievable through motorized intramedullary devices. While this technology mitigates some complications of external-fixation-based lengthening, many complications common to all lengthening procedures persist. New challenges and complications exclusive to this newer technology are also presented. The LL surgeon should be aware of and ready to respond to complications involving device malfunctions, poor local bony and soft-tissue biology, patient compliance, neurovascular compromise, joint instability, regenerate problems, and others. While technology will continue to evolve, study of and adherence to foundational principles of LL will minimize risks and optimize patient outcomes.


Assuntos
Alongamento Ósseo/efeitos adversos , Alongamento Ósseo/métodos , Pinos Ortopédicos/efeitos adversos , Extremidades , Regeneração Óssea , Tecido Conjuntivo , Falha de Equipamento , Humanos , Instabilidade Articular , Cooperação do Paciente , Risco
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