What is the effect of lactoferrin on oral and jawbone tissue repair? A systematic review.

Currently, there is growing interest in the potential use of lactoferrin (LTF), a member of the transferrin family, for the improvement of tissue healing. In this sense, a literature search was conducted to integrate data published on the effect of LTF on jawbone repair. PubMed/MEDLINE, Scopus, Embase, Web of Science, LILACS, and Cochrane databases were retrieved according to the PRISMA 2020 statement. Articles in English, Spanish, and Portuguese were recovered, with no year restriction. In vitro, in vivo, and clinical studies were selected. A total of 742 articles were retrieved, 11 of which met the inclusion criteria (5 in vitro and 5 in vivo studies, and one clinical trial). The included data demonstrated wide variations in study design and LTF therapy protocols. Cell proliferation and viability were the primary outcomes evaluated in the in vitro studies, all of which reported a potential effect of LTF on the repair process. Of three in vivo studies, one reported a reduction in the overall healing rate, whereas the other two showed that LTF inhibited bone resorption and increased bone formation. The clinical trial's findings showed that LTF is a potential promoter of wound repair in patients with medication-related osteonecrosis of the jaws. Overall, data from the studies support a potential effect of LTF therapy on the process of jawbone repair.

Percutaneous treatments of primary aneurysmal bone cysts: systematic review and meta-analysis.

PURPOSE: To systematically review the literature to determine recurrence rates of percutaneous treatments for primary aneurysmal bone cysts (ABC). METHODS: Search strategies were performed in the following databases: PubMed, SCIELO, LILACS and BVS, using terms in English, Spanish and Portuguese (PROSPERO Registration Number: CRD42020170340). Longitudinal studies, either observational or clinical trials, with at least five patients and with a mean of 18 months of follow-up were included. Studies had to use any type of percutaneous treatments and report the recurrence rates of primary ABC treatment. Studies selection, data extraction and risk of bias assessment were performed independently by two researchers. A global meta-analysis was carried out to assess the proportion of recurrence. Studies were categorized into two subgroups: selective arterial embolization and sclerotherapy. RESULTS: Thirteen studies were included in the present study. The average success rate of percutaneous treatments for ABC was 91.11%, with a total of 37 lesions recurrences in the 416 patients. The sex ratio was 1:1. The subgroup of sclerotherapies presented a lower proportion of recurrence. The proportion of recurrence in the subgroup of selective arterial embolization was 19% (95%IC 12.11-27.54) and that of sclerotherapies was 6% (95%IC 3.65-9.19). CONCLUSIONS: Both percutaneous treatments for ABC are effective, showing a lower rate of recurrence. Sclerotherapy treatments seem to be promising, but further clinical trials must be conducted with a longer follow-up.

Acidentes com material biológico no dia-a-dia da clínica odontológica: como proceder? / Accidents with biological material in day-to-day odontological clinic: what to do?

O estudo em questão objetiva esclarecer as condutas que o cirurgião-dentista e seus auxiliares devem tomar frente a acidentes com material biológico, durante a prática odontológica. Neste artigo, serão abordados os principais patógenos de risco durante a exposição, as medidas a serem tomadas, o acompanhamento sorológico, bem como a prevenção. O profissional deve, junto aos colegas da clínica médica, imediatamente após o acidente, realizar a avaliação do risco e do tratamento, que pode incluir desde cuidados locais na área exposta, medidas de quimioprofilaxia, bem como o acompanhamento sorológico para a Hepatite B, C e AIDS, e uma terapia de apoio psicológico

Transplante autógeno de germe de terceiro molar inferior com rizogênese completa para alvéolo de primeiro molar inferior / Autogenous transplantation of lower lip molar with complete rizogenesis to lower first molar alveolus

Os autores realizam um estudo da bibliografia sobre os transplantes dentais, assim como mostram caso clínico de um transplante autógeno de terceiro molar inferior com rizogênese completa. Mostram claramente o sucesso da manobra e a conseqüente eficiência do tratamento

Transplante autógeno - caso clínico: avaliação clínico-radiográfica / Autogenous transplant - clinical case: evaluation clinical - radiographic

Tem sido propostas várias técnicas clínicas e cirúrgicas para a manutenção do elemento dental. No entanto, em algumas situações extermas, a exodontia ainda têm suas indicações. O objetivo deste trabalho foi possibilitar ao paciente uma técnica acessível de substituição de um primeiro molar que seria perdido, por um terceiro molar retido e com rizogênese incompleta através da técnica de transplantação dental. A paciente vem sendo avaliada periodicamente há nove anos com resultados satisfatórios