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Opt Lett ; 48(14): 3785-3788, 2023 Jul 15.
Artigo em Inglês | MEDLINE | ID: mdl-37450750

RESUMO

We demonstrate the feasibility of a multimodal adaptive optics flood-illumination ophthalmoscope, able to provide both bright-field and dark-field images (such as phase contrast). The multimodality was made possible by integrating a digital micromirror device (DMD) at the illumination path to project a sequence of complementary high-resolution patterns into the retina. Through a versatile post-processing method that digitally selects backscattered or multiply scattered photons, we were able: (1) to achieve up to four-fold contrast increase of bright-field images when imaging the photoreceptor mosaic and nerve fibers; and (2) to visualize translucent retinal features such as capillaries, red blood cells, vessel walls, ganglion cells, and photoreceptor inner segments through phase contrast.


Assuntos
Iluminação , Células Fotorreceptoras Retinianas Cones , Células Fotorreceptoras Retinianas Cones/fisiologia , Inundações , Tomografia de Coerência Óptica/métodos , Retina/diagnóstico por imagem , Oftalmoscópios
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