Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 1 de 1
Filtrar
Mais filtros








Base de dados
Intervalo de ano de publicação
1.
Am J Trop Med Hyg ; 103(3): 1009-1016, 2020 09.
Artigo em Inglês | MEDLINE | ID: mdl-32588804

RESUMO

For the last decade, the New Jersey (NJ) Department of Health has reported between 42 and 144 new cases each year of "spotted fever group rickettsiosis" (SFGR), a statistic that reflects uncertainty regarding which rickettsial agents (Proteobacteria: Rickettsiaceae: Rickettsia) are infecting NJ residents. To identify the Rickettsia circulating in NJ ticks, we used a combination of conventional and real time PCR approaches to screen 560 Dermacentor variabilis Say and 245 Amblyomma americanum L. obtained from a 1-day state-wide surveillance in May 2018 and an additional 394 D. variabilis collected across NJ in 2013-2018. We found zero D. variabilis infected with Rickettsia rickettsii, the agent of Rocky Mountain spotted fever and, on average, 1.3% infected with presumed nonpathogenic Rickettsia montanensis. We also found zero A. americanum infected with R. rickettsii, and 20% infected with Rickettsia amblyommatis, a prevalence somewhat lower than in more southern states. Overall, we conclude that it is unlikely that R. rickettsii vectored by D. variabilis is a primary cause of SFGR cases in NJ and discuss our findings in the context of known facts and current limitations. We conclude that understanding the causes of SFGR east of the Mississippi will require collaboration among medical doctors, public health authorities, and medical entomologists to follow up presumptive human cases of SFGR with detailed histories of exposure, species-specific molecular assays, and active surveillance of putative vectors and the pathogens they may carry.


Assuntos
Vetores Aracnídeos/microbiologia , Dermacentor/microbiologia , Ixodes/microbiologia , Febre Maculosa das Montanhas Rochosas/epidemiologia , Rickettsiose do Grupo da Febre Maculosa/epidemiologia , Animais , Técnicas de Tipagem Bacteriana , DNA Bacteriano/genética , Humanos , Larva/microbiologia , New Jersey/epidemiologia , Ninfa/microbiologia , Reação em Cadeia da Polimerase em Tempo Real , Rickettsia/classificação , Rickettsia/genética , Rickettsia/isolamento & purificação , Rickettsia rickettsii/classificação , Rickettsia rickettsii/genética , Rickettsia rickettsii/isolamento & purificação , Febre Maculosa das Montanhas Rochosas/transmissão , Rickettsiose do Grupo da Febre Maculosa/transmissão
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA