RESUMO
Introducción: Con el propósito de justificar la decisión diplomática de los Estados Unidos, se publicaron dos artículos científicos en revistas médicas que intentan sostener la idea de que en La Habana hubo un ataque dirigido a personal de la embajada estadounidense. Objetivo: Demostrar la falta de rigor científico en dos investigaciones de series de casos no independientes sobre los síntomas de salud de diplomáticos de los Estados Unidos en La Habana. Método: Se realiza un análisis documental de dos publicaciones de series de casos. Se evalúan hipótesis diagnósticas. Resultados: Existe superposición amplia entre las dos series en cuanto a pacientes compartidos y en contraste se presentan algunas diferencias en los datos clínicos que superan lo esperado. Conclusiones: En ambas publicaciones se desaprovecha la riqueza semiográfica de síntomas y la información psicosocial. Se enfatiza más en argumentos asociados al fetichismo de la tecnología expresado en la interpretación de hallazgos inespecíficos. El análisis de datos clínicos permitió ver que se trata de un grupo heterogéneo de personas cuyas quejas de salud han sido reunidas por la interacción de otros factores psicosociales contextuales(AU)
Introduction: In order to justify the diplomatic decision of the United States, two scientific articles were published in medical journals that attempt to support the idea that, in Havana, there was an attack aimed at US embassy personnel. Objective: To prove the lack of scientific consistency in two investigations of non-independent case series on the health symptoms of United States diplomats in Havana. Method: A documentary analysis of two publications of case series is carried out. Diagnostic hypotheses are evaluated. Results: There is wide overlap between the two series in terms of shared patients and in contrast there are some differences in the clinical data that exceed what was expected. Conclusions: In both publications the semiographic wealth of symptoms and psychosocial information are wasted. More emphasis is placed on arguments associated with the fetishism of technology expressed in the interpretation of nonspecific findings. The analysis of clinical data allowed us to see that it is a heterogeneous group of people whose health complaints have been brought together by the interaction of other contextual psychosocial factors(AU)
Assuntos
Humanos , Política , Pesquisa , Síndrome , Tecnologia , Tontura/etiologia , Cefaleia do Tipo Tensional/etiologiaRESUMO
BACKGROUND: Imaging the lower extremity reproducibly and accurately remains an elusive goal. This is particularly true in the high risk diabetic foot, where tissue loss, edema, and color changes are often concomitant. The purpose of this study was to evaluate the reproducibility of a novel and inexpensive stereotaxic frame in assessment of wound healing. METHODS: The main idea is to keep constant and reproducible the relative position of extremities related to the sensor used for the examination during a serial studies by stereotaxic digital photographic sequence. Ten healthy volunteers were evaluated at 10 different time moments to estimate the foot position variations in the stereotaxic frame. The evolution of 40 of DFU patients under treatment was evaluated before and during the epidemical grow factor intralesional treatment. RESULTS: The wound closing and granulation speeds, the relative contribution of the contraction and tissue restauration mechanism were evaluated by stereotaxic digital photography. CONCLUSIONS: The results of this study suggest that the stereotaxic frame is a robust platform for serial study of the evolution of wound healing which allow to obtain consistent information from a variety of visible and hyperspectral measurement technologies. New stereotaxic digital photography evidences related to the diabetic foot ulcer healing process under treatment has been presented.
Assuntos
Pé Diabético/diagnóstico por imagem , Diagnóstico por Imagem/métodos , Fotografação/métodos , Técnicas Estereotáxicas , Adulto , Diagnóstico por Imagem/instrumentação , Feminino , Humanos , Interpretação de Imagem Assistida por Computador/métodos , Masculino , Fotografação/instrumentação , Técnicas Estereotáxicas/instrumentaçãoRESUMO
Extraordinarily small (2.4 nm) cobalt ferrite nanoparticles (ESCIoNs) were synthesized by a one-pot thermal decomposition approach to study their potential as magnetic resonance imaging (MRI) contrast agents. Fine size control was achieved using oleylamine alone, and annular dark-field scanning transmission electron microscopy revealed highly crystalline cubic spinel particles with atomic resolution. Ligand exchange with dimercaptosuccinic acid rendered the particles stable in physiological conditions with a hydrodynamic diameter of 12 nm. The particles displayed superparamagnetic properties and a low r2/ r1 ratio suitable for a T1 contrast agent. The particles were functionalized with bile acid, which improved biocompatibility by significant reduction of reactive oxygen species generation and is a first step toward liver-targeted T1 MRI. Our study demonstrates the potential of ESCIoNs as T1 MRI contrast agents.
RESUMO
Se realizó un estudio descriptivo para determinar el comportamiento del servicio de los tomógrafos de resonancia magnética cubanos Giroimag-01 y Giroimag-02, desarrollados por el Centro de Biofísica Médica de Santiago de Cuba, durante el período comprendido entre 1996 y 1998, a partir del análisis comparativo de los informes estadísticos mensuales, semestrales y anuales del servicio prestado con estos equipos y teniendo en cuenta los pacientes atendidos en el trienio, la positividad registrada y las lesiones más comúnmente diagnosticadas. A modo de conclusión se relacionan los factores que han condicionado la favorable evolución del servicio prestado por dichos tomógrafos, donde se destaca la necesidad y conveniencia de continuar su generalización en el Sistema Nacional de Salud cubano