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1.
Acta Otorrinolaringol Esp ; 62(6): 443-7, 2011.
Artigo em Espanhol | MEDLINE | ID: mdl-21958675

RESUMO

OBJECTIVE: The aim of this study was to determine the predictive value of computed tomography (CT) i.e., its sensitivity and specificity in detecting metastatic lymph nodes of head and neck tumours. We also studied the capacity of CT in correct nodal staging. PATIENTS AND METHODS: A CT was performed on 95 patients diagnosed with neoplastic disease of the pharynx and/or larynx. All patients subsequently underwent cervical lymph node dissections. In the imaging study, the following parameters were considered for suspected radiological nodal involvement: lymph node diameter greater than 10mm, lesion margins poorly defined, capsule enhancement after contrast administration and lymph nodes that, despite their size, had signs of central necrosis. RESULTS: In the dissections, 70.53% resulted N+ in the histological study. The sensitivity of CT was 82.09% and the specificity, 85.71%. The CT detected positivity in 55 of the 67 histologically pathological dissections, while the CT detected negativity in 24 of the 28 dissections histologically negative. The weighted kappa index value was 0.6408, indicating limited capacity for appropriate staging of the lymph nodes. CONCLUSIONS: While the ability of CT to detect metastatic lymph nodes in head and neck tumours is quite acceptable, it is less so for correctly staging them. It is therefore necessary to look for other imaging tests that provide greater accuracy to avoid unnecessary elective neck dissections and to reduce morbidity and mortality from them. We must now pay attention to new imaging techniques such as PET and PET/CT.


Assuntos
Neoplasias de Cabeça e Pescoço/diagnóstico por imagem , Metástase Linfática/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Neoplasias de Cabeça e Pescoço/patologia , Humanos , Neoplasias Laríngeas/diagnóstico por imagem , Neoplasias Laríngeas/patologia , Neoplasias Bucais/diagnóstico por imagem , Neoplasias Bucais/patologia , Imagem Multimodal , Pescoço , Esvaziamento Cervical , Neoplasias Faríngeas/diagnóstico por imagem , Neoplasias Faríngeas/patologia , Tomografia por Emissão de Pósitrons , Valor Preditivo dos Testes , Procedimentos Desnecessários
2.
Clin Rheumatol ; 27(1): 107-10, 2008 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-17982708

RESUMO

Schnitzler's syndrome is a rare combination of chronic urticaria, fever of unknown origin, disabling bone pain, and monoclonal gammopathy. We report a case with an unusual radiological manifestation as a solitary sclerotic lesion of the right iliac bone. Its main features on conventional radiography, computed tomography, and magnetic resonance imaging are described, and the main radiological differential diagnoses are discussed to help with the characterization of this syndrome, which requires a combination of clinical, laboratory, and radiological data. On the other hand, although our patient had an excellent clinical response to anakinra, the sclerotic lesion remained unchanged on follow-up X-ray examinations.


Assuntos
Diagnóstico por Imagem/métodos , Síndrome de Schnitzler/diagnóstico por imagem , Síndrome de Schnitzler/patologia , Adulto , Antirreumáticos/uso terapêutico , Quimioterapia Combinada , Humanos , Ílio/diagnóstico por imagem , Ílio/patologia , Imunossupressores/uso terapêutico , Proteína Antagonista do Receptor de Interleucina 1/uso terapêutico , Imageamento por Ressonância Magnética , Masculino , Metotrexato/uso terapêutico , Dor/tratamento farmacológico , Dor/patologia , Síndrome de Schnitzler/tratamento farmacológico , Esclerose/patologia , Tomografia Computadorizada por Raios X , Resultado do Tratamento , Urticária/tratamento farmacológico , Urticária/patologia
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