1.
Org Lett
; 2(16): 2393-5, 2000 Aug 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-10956504
RESUMO
(S)-(-)-2-Diazo-1-oxiranyl-ethanone, prepared in two steps from (R)-(+)-glycidol, has been employed as an intermediate in several characteristic diazocarbonyl reactions to yield novel, nonracemic products including an epoxy quinoxaline and epoxy thiazoles and oxazoles.
2.
Bioorg Med Chem Lett
; 10(2): 153-5, 2000 Jan 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-10673100
RESUMO
The reductive amination of an amino acid derived glyoxal, with the free amino group of a protected amino acid or oligopeptide fragment, has been developed as a simple and efficient method for the preparation of ketomethylene amino pseudo-oligopeptide isosteres Aa psi(COCH2NH)Aa. Trichlorosilane-DMF is the reagent of choice for the reduction.
Assuntos
Aminoácidos/química , Glioxal/análogos & derivados , Peptídeos/síntese química , Aminação , Espectroscopia de Ressonância Magnética , Oxirredução , Estereoisomerismo
3.
Am J Med
; 96(1): 95-6, 1994 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-8304371