1.
Clin Perinatol
; 38(4): 703-17, 2011 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22107899
RESUMO
Early-life adversity can affect brain development and behavior. Emerging evidence from studies on both humans and rodents suggests that epigenetic mechanisms may play a critical role in shaping our biology in response to the quality of the environment. This article highlights the research findings suggesting that prenatal maternal stress, postnatal maternal care, and infant neglect/abuse can lead to epigenetic variation, which may have long-term effects on stress responsivity, neuronal plasticity, and behavior.