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1.
Philos Trans A Math Phys Eng Sci ; 378(2178): 20190493, 2020 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-32713314

RESUMO

Initial selection of tidal stream energy sites is primarily based on identifying areas with the maximum current speeds. However, optimal design and deployment of turbines requires detailed investigations of the temporal variability of the available resource, focusing on areas with reduced variability, and hence the potential for more continuous energy supply. These aspects are investigated here for some of the most promising sites for tidal array development across the north-western European shelf seas: the Alderney Race, the Fromveur Strait, the Pentland Firth and the channels of Orkney. Particular attention was dedicated to asymmetry between the flood and ebb phases of the tidal cycle (due to the phase relationship between M2 and M4 constituents), and spring-neap variability of the available resource (due to M2 and S2 compound tides). A series of high-resolution models were exploited to (i) produce a detailed harmonic database of these three components, and (ii) characterize, using energy resource metrics, temporal variability of the available power density. There was a clear contrast between the Alderney Race, with reduced temporal variability over semi-diurnal and fortnightly time scales, and sites in western Brittany and North Scotland which, due to increased variability, appeared less attractive for optimal energy conversion. This article is part of the theme issue 'New insights on tidal dynamics and tidal energy harvesting in the Alderney Race'.

2.
Philos Trans A Math Phys Eng Sci ; 378(2178): 20190498, 2020 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-32713317

RESUMO

The tides are a predictable, renewable, source of energy that, if harnessed, can provide significant levels of electricity generation. The Alderney Race (AR), with current speeds that exceed 5 m s-1 during spring tides, is one of the most concentrated regions of tidal energy in the world, with the upper-bound resource estimated at 5.1 GW. Owing to its significance, the AR is frequently used for model case studies of tidal energy conversion, and here we review these model applications and outcomes. We examine a range of temporal and spatial modelling scales, from regional models applied to resource assessment and characterization, to more detailed models that include energy extraction and array optimization. We also examine a range of physical processes that influence the tidal energy resource, including the role of waves and turbulence in tidal energy resource assessment and loadings on turbines. The review discusses model validation, and covers a range of numerical modelling approaches, from two-dimensional to three-dimensional tidal models, two-way coupled wave-tide models, Large Eddy Simulation (LES) models, and the application of optimization techniques. The review contains guidance on model approaches and sources of data that can be used for future studies of the AR, or translated to other tidal energy regions. This article is part of the theme issue 'New insights on tidal dynamics and tidal energy harvesting in the Alderney Race'.

3.
Int J Clin Exp Hypn ; 66(2): 134-146, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29601275

RESUMO

This two-center quasiexperimental pilot study was to determine the effect of conversational hypnosis on patient comfort and parasympathetic tone, which may represent a quantitative measure of hypnotic depth, during regional anesthesia. The patients received conversational hypnosis in one center and oral premedication in the other. The patients' subjective comfort (0-10 rating scale) and objective parasympathetic tone, as assessed by the Analgesia/Nociception Index (ANI), were measured before and after regional anesthesia. The parasympathetic tone and comfort scores evidenced a significantly greater increase in the hypnosis patients than in controls. These findings suggest that using conversational hypnosis during regional anesthesia may be followed by a subjective increase in patient comfort and an objective increase in parasympathetic tone, monitored by ANI.


Assuntos
Braço/cirurgia , Bloqueio do Plexo Braquial/métodos , Hipnose/métodos , Conforto do Paciente/métodos , Adulto , Bloqueio do Plexo Braquial/efeitos adversos , Bloqueio do Plexo Braquial/psicologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Sistema Nervoso Parassimpático/fisiologia , Projetos Piloto , Estudos Prospectivos
4.
Int J Clin Exp Hypn ; 65(1): 64-85, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-27935457

RESUMO

The purpose of this study was to evaluate the effects of a hypnotically-based intervention for pain and fear in women undergoing labor who are about to receive an epidural catheter. A group of 155 women received interventions that included either (a) patient rocking, gentle touching, and hypnotic communication or (b) patient rocking, gentle touching, and standard communication. The authors found that the hypnotic communication intervention was more effective than the standard communication intervention for reducing both pain intensity and fear. The results support the use of hypnotic communication just before and during epidural placement for women who are in labor and also indicate that additional research to evaluate the benefits and mechanism of this treatment is warranted.


Assuntos
Doulas/psicologia , Medo/psicologia , Hipnose Anestésica/métodos , Dor do Parto/terapia , Adulto , Feminino , Humanos , Hipnose Anestésica/psicologia , Dor do Parto/psicologia , Pessoa de Meia-Idade , Gravidez
5.
Anesth Analg ; 97(3): 843-847, 2003 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-12933413

RESUMO

In a randomized, double-blinded study, we evaluated the analgesic effect of ketamine in the management of pain in a surgical intensive care unit after major abdominal surgery. Patients received morphine patient-controlled analgesia with either placebo (Group M) or ketamine (Group K). Morphine was administered with initial loading doses of 2 mg until the visual analog scale (VAS) score was <30 and thereafter with bolus doses of 1 mg and a lockout time of 7 min. Ketamine was administered with an initial bolus of 0.5 mg/kg followed by a perfusion of 2 micro g x kg(-1) x min(-1) during the first 24 h and 1 micro g x kg(-1) x min(-1) during the following 24 h. The 4-h cumulative morphine doses were measured over 48 h. The VAS scores at rest and at mobilization were measured every 4 h during 48 h. A total of 101 patients were enrolled, and 93 were analyzed (41 in Group K and 52 in Group M). VAS scores at rest and at mobilization were similar. The cumulative consumption of morphine was significantly smaller in Group K (P < 0.05). We concluded that small doses of ketamine were a valuable adjunct to opioids in surgical intensive care unit patients after major abdominal surgery.


Assuntos
Analgésicos Opioides/uso terapêutico , Anestésicos Dissociativos/uso terapêutico , Ketamina/uso terapêutico , Morfina/uso terapêutico , Dor Pós-Operatória/tratamento farmacológico , Abdome/cirurgia , Idoso , Analgésicos Opioides/administração & dosagem , Analgésicos Opioides/efeitos adversos , Anestésicos Dissociativos/administração & dosagem , Cuidados Críticos , Método Duplo-Cego , Quimioterapia Combinada , Feminino , Humanos , Ketamina/administração & dosagem , Masculino , Pessoa de Meia-Idade , Morfina/administração & dosagem , Morfina/efeitos adversos , Medição da Dor , Estudos Prospectivos
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