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Surg Infect (Larchmt) ; 25(4): 272-290, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38700753

RESUMO

Background: Improvements in liver transplant (LT) outcomes are attributed to advances in surgical techniques, use of potent immunosuppressants, and rigorous pre-LT testing. Despite these improvements, post-LT infections remain the most common complication in this population. Bacteria constitute the most common infectious agents, while fungal and viral infections are also frequently encountered. Multi-drug-resistant bacterial infections develop because of polymicrobial overuse and prolonged hospital stays. Immediate post-LT infections are commonly caused by viruses. Conclusions: Appropriate vaccination, screening of both donor and recipients before LT and antiviral prophylaxis in high-risk individuals are recommended. Antimicrobial drug resistance is common in high-risk LT and associated with poor outcomes; epidemiology and management of these cases is discussed. Additionally, we also discuss the effect of coronavirus disease 2019 (COVID-19) infection and monkeypox in the LT population.


Assuntos
COVID-19 , Transplante de Fígado , Transplantados , Humanos , Infecções Bacterianas/epidemiologia , Infecções Bacterianas/tratamento farmacológico , Infecções Bacterianas/prevenção & controle , COVID-19/epidemiologia , Transplante de Fígado/efeitos adversos , Micoses/epidemiologia , Micoses/tratamento farmacológico , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/prevenção & controle , SARS-CoV-2 , Viroses/epidemiologia , Viroses/prevenção & controle
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