Initial tweet valence, abuse volume, and observer Dark Tetrad characteristics influence perceptions of female celebrity abuse on Twitter.

Research into relationships between victim-generated content, abuse received, and observer characteristics when considering Twitter abuse has been limited to male victims. We evaluated participant perceptions of female celebrity victims and abuse received on Twitter. We used a 3 (Initial Tweet Valence; negative, neutral, positive) × 2 (Abuse Volume; low, high) repeated measures design and online survey method. Participants were shown tweets generated by six female celebrities, counterbalanced such that each participant saw each celebrity in one Valence-Volume condition. Stimuli were presented across six 'lists' such that celebrity 'victims' could be rotated across Valence-Volume pairings. Participants rated-per target stimulus-the level of blame attributable to the victim and the perceived severity of the incident. Furthermore, participants were asked to complete a Dark Tetrad scale-measuring their Machiavellianism, Narcissism, Psychopathy, and Sadism. Analyses determined that victim-blaming was influenced by victim Initial Tweet Valence (greater victim-blaming associated with more-negative content) and observer Machiavellianism. Perceived severity was influenced by victim Initial Tweet Valence, Volume of Abuse received, and observer Machiavellianism. Results were consistent with previous research involving male celebrity victims. Further research is needed to understand the contributions of participants' hostile and benevolent sexism, as well as the role of victim attractiveness.

The Impact of Mental Illness and Intellectual Disability Information on General Public Perceptions of a Person Convicted of a Child Sex Offence.

A person convicted of sex offences (PCSO) is confronted with several challenges upon re-entry to the community, often facing difficulties accessing housing and employment, and experiencing stigmatisation, hostility and harassment from community members. Given the importance of community support for successful reintegration, we examined differences in public (N = 117) attitudes toward a PCSO against a child (PCSO-C) with mental illness or intellectual disability compared to a neurotypical PCSO-C in an online survey. At present, differences in attitudes towards these groups has not been explored. Results indicated the PCSO-Cs with intellectual disability or mental illness were seen to pose less risk of sexual reoffending and prompted higher levels of reintegration comfort than the neurotypical PCSO-C. Participants' prior personal exposure to mental illness or intellectual disability was unrelated to attitudes, but those who believed that PCSOs in general have a low capacity for change attributed greater risk of sexual reoffending, greater risk of future harm to children, higher levels of blame and lower reintegration comfort, regardless of MI and ID information. Female participants also perceived greater risk of future harm to adults, and older participants estimated higher risk of sexual reoffending than younger participants. Findings have implications for community acceptance of PCSO-Cs and jury decision-making processes and highlight the importance of public education regarding neurodiverse PCSO-Cs and PCSO capacity for change to encourage knowledge-based judgements.

The impact of post-encoding alcohol consumption on episodic memory recall and remember-know responses in heavy drinkers.

Introduction: People often consume alcohol following trauma, particularly in response to distressing memories. To date, little is known about how post-encoding alcohol consumption influences episodic memory recall for negative events. Understanding these effects may help to improve support for trauma victims - for example, witnesses and victims of crimes. Methods: We tested 60 participants who self-described as heavy drinkers. After watching an analog trauma film, half were allocated to consuming a moderate dose of alcohol (Alcohol-Exposed group), while half received a placebo drink (Placebo-Control group). Immediately and after a one-week delay, participants recalled the event via free and cued recall tasks. Participants also gave remember-know responses and confidence ratings, elucidating alcohol's effect on experiential memory. Results: Free recall performance was similar for the Alcohol-Exposed group and the Placebo-Control group during Sessions 1 and 2. The Alcohol-Exposed group benefitted more from the delayed repeated retrieval attempt. For the cued recall task, the Alcohol-Exposed group provided more "Do not Know" responses compared to the Placebo-Control group in both sessions. For the Alcohol-Exposed group only "Correct Know" responses increased from Session 1 to 2. Although memory performance improved across sessions, confidence levels decreased from Session 1 to 2 in the Alcohol-Exposed group. Discussion: Post-encoding alcohol consumption appears to impact immediate episodic memory retrieval; however, this effect is only temporary in nature. No evidence was found that alcohol primarily reduces remembering responses. Much like previous findings focusing on pre-encoding alcohol consumption (Hagsand et al., 2017), current findings suggest that providing individuals who drank alcohol after witnessing an incident with a delayed repeated retrieval attempt can lead to more complete and accurate testimonies.

Dual-task decrements in mono-, bi- and multilingual participants: Evidence for multilingual advantage.

Evidence suggests that language processing in bilinguals is less left-lateralized than in monolinguals. We explored dual-task decrement (DTD) for mono-, bi- and multilinguals in a verbal-motor dual-task paradigm. We expected monolinguals to show greater DTD than bilingual participants, who would show greater DTD than multilingual participants. Fifty right-handed participants (18 monolingual, 16 bilingual, 16 multilingual) completed verbal fluency and manual motor tasks in isolation and concurrently. Tasks were completed twice in isolation (left-handed, right-handed) and twice as dual-tasks (left-handed, right-handed); participants' motor-executing hands served proxy for hemispheric activation. Results supported the hypotheses. Completing dual-tasks incurred greater cost for manual motor tasks than for verbal fluency tasks. Negative cost of performing dual-tasks diminished as number of languages spoken increased; in fact, multilingual individuals demonstrated a dual-task advantage in both tasks when using the right hand, strongest in the verbal task. Dual-tasking had the greatest negative impact on verbal fluency of monolingual participants when the motor task was completed with the right hand; for bi- and multi-lingual participants, the greatest negative impact on verbal fluency was seen when the motor task was completed with the left hand. Results provide support for the bi-lateralization of language function in bi- and multilingual individuals.

Emoji Identification and Emoji Effects on Sentence Emotionality in ASD-Diagnosed Adults and Neurotypical Controls.

We investigated ASD-diagnosed adults' and neurotypical (NT) controls' processing of emoji and emoji influence on the emotionality of otherwise-neutral sentences. Study 1 participants categorised emoji representing the six basic emotions using a fixed-set of emotional adjectives. Results showed that ASD-diagnosed participants' classifications of fearful, sad, and surprised emoji were more diverse and less 'typical' than NT controls' responses. Study 2 participants read emotionally-neutral sentences; half paired with sentence-final happy emoji, half with sad emoji. Participants rated sentence + emoji stimuli for emotional valence. ASD-diagnosed and NT participants rated sentences + happy emoji as equally-positive, however, ASD-diagnosed participants rated sentences + sad emoji as more-negative than NT participants. We must acknowledge differential perceptions and effects of emoji, and emoji-text inter-relationships, when working with neurodiverse stakeholders.

Beyond tingles: An exploratory qualitative study of the Autonomous Sensory Meridian Response (ASMR).

This qualitative exploratory study investigated the embodied experiences and the meanings of Autonomous Sensory Meridian Response (ASMR) from the viewer's perspective. ASMR research has been sparse and largely quantitative, assuming it to be a predominantly fixed physiological response of "tingles", despite the acronym being rooted in pseudoscience. A qualitative research design was adopted to facilitate the exploratory nature of the study in this under-researched area. In contrast to the mostly survey-based research on ASMR, this study employed semi-structured interviews as a means to understand the lived experience of ASMR and to promote participant agency. Six self-identifying ASMR consumers were recruited using a mixture of snowball and opportunity sampling. Semi-structured interviews were conducted both in person and using Skype to facilitate transnational data collection. Interview transcripts were analysed using an inductive, data-driven approach to thematic analysis. The analysis suggests that ASMR is felt to provide a social environment of comfort rather than a solely physiological-based experience. Three key themes emerged: who and what defines ASMR? (reflecting the variety of what was classed as ASMR and what content was consumed to produce the response); "real" intimacy tailored to me (reflecting the idiosyncratic perception of intimacy made possible through ASMR); and emotional relief on my terms (reflecting the role of ASMR in self-soothing). The present data reflect a rich, complex experience of the ASMR consumer, pointing to potential wider applications and informing further research.

Exploring the effects of COVID-19 restrictions on wellbeing across different styles of lockdown.

Countries have instigated different restrictions in response to the COVID-19 pandemic. For instance, nationwide, strict "lockdown" in Scotland was enacted with breaches punishable by law, whereas restrictions in Japan allowed for travel and interaction, with citizens requested rather than required to conform. We explored the impact of these differential strategies on health behaviours and wellbeing. In February 2021, 138 Scottish and 139 Japanese participants reported their demographic information, pandemic-induced health behaviour-change (alcohol consumption, diet, perceived sleep quality, physical activity), negative mood, and perceived social isolation. Scottish participants' health behaviours were characterised by greater change (typically negative), most likely due to greater lifestyle disruption, whereas Japanese participants' behaviours were more-stable. Negative changes to health behaviours were typically associated with poorer mental wellbeing and isolation. Interestingly though, Japanese participants reported greater negative mood but not isolation despite the less-restrictive lockdown. Taken together, different lockdown styles led to different changes in health behaviours.

Intimate Partner Stalking/Pursuit: A Pathophysiology of Attachment Style.

Approximately half of stalking victims were previously in an intimate relationship with the perpetrator, and attachment style is strongly correlated with intimate partner stalking (IPS). In the first study to investigate polyvagal theory in IPS, we examined 58 adult participants' attachment style, sex, history of IPS, vagal tone activity (i.e., heart rate variability; HRV), and cognitive processing disruptions (i.e., Stroop performance) in either participants who wished a relationship or in those who wished to maintain a relationship post-break-up. Results showed that males were more likely to perpetrate IPS than females. Anxious-style participants were more likely to have perpetrated IPS, showed greater cognitive disruption and HRV than avoidant-style participants. Our results support theories that attachment is a biological imperative with neurobiological implications that can be indexed physiologically and cognitively. This study is the first to demonstrate a pathophysiology of attachment style to IPS, in a replicable way. IPS is discussed as reflective of disordered arousal and related to anxiety. Recommendations for further research and clinically-relevant interventions are presented.

Social isolation during COVID-19 lockdown impairs cognitive function.

Studies examining the effect of social isolation on cognitive function typically involve older adults and/or specialist groups (e.g., expeditions). We considered the effects of COVID-19-induced social isolation on cognitive function within a representative sample of the general population. We additionally considered how participants 'shielding' due to underlying health complications, or living alone, performed. We predicted that performance would be poorest under strictest, most-isolating conditions. At five timepoints over 13 weeks, participants (N = 342; aged 18-72 years) completed online tasks measuring attention, memory, decision-making, time-estimation, and learning. Participants indicated their mood as 'lockdown' was eased. Performance typically improved as opportunities for social contact increased. Interactions between participant sub-groups and timepoint demonstrated that performance was shaped by individuals' social isolation levels. Social isolation is linked to cognitive decline in the absence of ageing covariates. The impact of social isolation on cognitive function should be considered when implementing prolonged pandemic-related restrictive conditions.

Corrigendum: Changes in Diet, Sleep, and Physical Activity Are Associated With Differences in Negative Mood During COVID-19 Lockdown.

[This corrects the article DOI: 10.3389/fpsyg.2020.588604.].

Changes in Diet, Sleep, and Physical Activity Are Associated With Differences in Negative Mood During COVID-19 Lockdown.

The United Kingdom and Scottish governments instigated a societal lockdown in response to the COVID-19 pandemic. Subsequently, many experienced substantial lifestyle changes alongside the stresses of potentially catching the virus or experiencing bereavement. Stressful situations and poorer health behaviors (e.g., higher alcohol consumption, unhealthy diet, poorer sleep quality, physical inactivity) are frequently linked to poor mental health. Our objective was to examine changes in health behaviors and their relationship with negative mood during COVID-19 lockdown. We also considered associations between health behaviors and socio-demographic differences and COVID-19-induced changes. 399 participants completed a questionnaire asking about their personal situation and health behaviors during lockdown as well as a negative mood scale. The significance threshold for all analyses was α = 0.05. Poorer diet was linked to more-negative mood, and to changes to working status. Poorer sleep quality was linked with more-negative mood, and with 'shielding' from the virus. Being less physically active was related to more-negative mood and student status, whereas being more physically active was linked to having or suspecting COVID-19 infection within the household. Increased alcohol consumption was linked to living with children, but not to negative mood. Changes to diet, sleep quality, and physical activity related to differences in negative mood during COVID-19 lockdown. This study adds to reports on poor mental health during lockdown and identifies lifestyle restrictions and changes to health behaviors which may, to some extent, be responsible for higher negative mood. Our data suggests that it is advisable to maintain or improve health behaviors during pandemic-associated restrictions.

Words from the wizarding world: Fictional words, context, and domain knowledge.

The influence of domain knowledge on reading behavior has received limited investigation compared to the influence of, for example, context and/or word frequency. The current study tested participants with and without domain knowledge of the Harry Potter (HP) universe. Fans and non-fans read sentences containing HP, high-frequency (HF), or low-frequency target-words. Targets were presented in contexts that were supportive or unsupportive within a 2 (group: fans, non-fans) × 3 (context: HP, HF, LF) × 3 (word type: HP, HF, LF) mixed design. Thirty-two fans and 22 non-fans read 72 two-sentence experimental items while eye-movement behavior was recorded: Initial sentences established context; second sentences contained target-words. Fans processed HP words faster than non-fans. No group difference was observed on HF or LF processing durations, suggesting equivalent reading capabilities. In HP contexts, HP and LF targets were processed equivalently. Processing of HF and LF words was facilitated by their supportive context as expected. Non-fans made more regressions into the target region in HP contexts and regressed more into HP targets than other targets; fans regressed into target word regions equivalently across all context and word types. Results suggest that domain knowledge influences early but not immediate lexical access, while the processing effect of novelty was seen in regressive eye movements. These results are more supportive of modular accounts of linguistic processing and serial models of eye movement control. Words without grounding in reality, or true embodiment, were integrated into fans' mental lexicons. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

Analytical validation of new ELISAs for the quantitation of polyclonal free light chains and comparison to existing assays for healthy and patient samples.

BACKGROUND: Polyclonal FLCs can be used as a biomarker of inflammation and immune activation in a range of diseases. This study evaluated the performance of new FLC ELISAs (Seralite FLC ELISA) for the quantitation of polyclonal κ and λ FLC, including comparisons to existing assays. METHODS: Technical performance was assessed for the ELISA and reference ranges were generated using healthy donor serum (N = 91). Patients with a range of conditions associated with polyclonal FLC dysregulation (N = 164) were measured across platforms. RESULTS: The ELISAs generated references ranges of: 8.72-23.0 mg/L κ FLC, and 8.52-25.24 mg/L for λ FLC. ELISAs demonstrated linearity across the calibration range and intra-assay (≤ 8.7%) and inter-assay (≤ 12.3%) imprecision was low. The limit of detection was 0.63 mg/L for κ and 0.57 mg/L for λ FLC. Minimal cross-reactivity was observed for interference agents, alternate FLC and whole immunoglobulin (median change ≤3.6 mg/L). Assays showed good batch-to-batch consistency. For patient samples, methods generated different κ and λ FLC concentrations and differences were seen between methods for the number of patients classified as below, with and above references ranges for κ and λ FLC. There was no significant difference in the FLC sum between the different techniques. CONCLUSIONS: The ELISAs displayed good analytical and technical performance. The quantification of individual κ and λ FLC appears inherently different between platforms. These differences are attenuated if using the FLC sum, which was similar between methods and provided agreement in relation to patients having normal or elevated FLCs.

Verification of representative data for output factors of SRS cones utilizing IAEA TRS 483 recommendations.

Measurements of small fields continue to be a clinical challenge despite the recent work done to identify their characteristics. Due to this challenge, many physicists use representative data supplied by their vendors to verify their own measurements for small field output factors. However, with recent guidelines being released in IAEA TRS 483, the question remains if this representative data provides an accurate representation for small field dosimetry. A Sun Nuclear EDGE detector, PTW 60012 stereotactic diode, and GafChromic EBT3 films were used to measure the output factor for a set of Varian SRS cones (4 mm-17.5 mm diameters) on a TrueBeam linear accelerator. The measured output factors were then compared to the Varian provided SRS representative data. IAEA TRS 483 recommendations for measuring small field output factors were applied and the impact of those recommendations were examined. The EDGE detector showed good agreement with the representative data when correction factors were not applied (0.01%-1.64% difference) but the PTW 60012 diode showed larger deviation (0.61%-3.35% difference). The EBT3 film showed the largest difference with the representative data (0.66%-9.19%). After application of IAEA TRS 483 detector specific correction factors the output factors measured by the diodes showed good agreement with the EBT3 film for 6MV (<1.8% difference) but showed a large deviation with the representative data (up to 9% difference). The 6FFF energy output factors agreed between the EDGE, the PTW 60012, and EBT3 Film. This work shows that the use of uncorrected representative data on the Truebeam can lead to a significant over estimation of the SRS cone output factors.

A New Technique Using 4DCT Scans to Create Custom Cardiac Blocks for Left-Sided Breast Cancer Treatments.

PURPOSE: For patients who receive treatment for left breast cancer, cardiac toxicity increases with increased radiation dose to the heart. A new method was developed using 4-dimensional computed tomography (CT) scans to improve custom cardiac blocks to minimize heart dose. METHODS AND MATERIALS: Four-dimensional CT scans were acquired, and a maximum intensity projection (MIP) heart was contoured for 20 patients. Custom heart blocks were created to fully block the MIP heart volume. A heart block based on the standard free-breathing (FB) CT image was retrospectively created. Differences in heart block sizes were compared. Differences in heart block areas and dose statistics were analyzed. RESULTS: In all 20 cases, the heart block created using the 4-dimensional scan had a larger area than the corresponding FB block. The mean increase in multileaf collimator coverage was 3.9 mm (range, 0.5-20.1 mm). The mean increase in the area of the heart block was 2.58 cm2 (range, 0.22-6.65 cm2). The dose-volume histogram showed that the MIP heart received 17.8 cGy (range, 0.02-70.3 cGy) more than the FB heart on average. Replanning with an FB heart block showed that the mean dose to the MIP heart increased by 16.2 cGy (range, 1.8-44.8 cGy) compared with the FB heart dose. CONCLUSIONS: Four-dimensional heart blocks accounting for intrinsic respiratory motion and cardiac motion were greater in size than FB heart blocks. These larger blocks resulted from the larger contour created from the MIP image and blocked more dose to the heart. This technique for improving custom heart blocks can be easily implemented with 4DCT machine capabilities that are currently available in clinical practice.

Testing the limits of contextual constraint: Interactions with word frequency and parafoveal preview during fluent reading.

Contextual constraint is a key factor affecting a word's fixation duration and its likelihood of being fixated during reading. Previous research has generally demonstrated additive effects of predictability and frequency in fixation times. Studies examining the role of parafoveal preview have shown that greater preview benefit is obtained from more predictable and higher frequency words versus less predictable and lower frequency words. In two experiments, we investigated effects of target word predictability, frequency and parafoveal preview. A 3 (Predictability: low, medium, high) × 2 (Frequency: low, high) design was used with Preview (valid, invalid) manipulated between experiments. With valid previews, we found main effects of Predictability and Frequency in both fixation time and fixation probability measures, including an interaction in early fixation measures. With invalid preview, we again found main effects of Predictability and Frequency in fixation times, but no evidence of an interaction. Fixation probability showed a weak Predictability effect and Predictability-Frequency interaction. Predictability interacted with Preview in early fixation time and fixation probability measures. Our findings suggest that high levels of contextual constraint exert an early influence during lexical processing in reading. Results are discussed in terms of models of language processing and eye movement control.

Development of a rapid and quantitative lateral flow assay for the simultaneous measurement of serum κ and λ immunoglobulin free light chains (FLC): inception of a new near-patient FLC screening tool.

BACKGROUND: Serum free light chains (FLC) are sensitive biomarkers used for the diagnosis and management of plasma cell dyscrasias, such as multiple myeloma (MM), and are central to clinical screening algorithms and therapy response criteria. We have developed a portable, near-patient, lateral-flow test (Seralite®) that quantitates serum FLC in 10 min, and is designed to eliminate sample processing delays and accelerate decision-making in the clinic. METHODS: Assay interference, imprecision, lot-to-lot variability, linearity, and the utility of a competitive-inhibition design for the elimination of antigen-excess ('hook effect') were assessed. Reference ranges were calculated from 91 healthy donor sera. Preliminary clinical validation was conducted by retrospective analysis of sera from 329 patients. Quantitative and diagnostic results were compared to Freelite®. RESULTS: Seralite® gave a broad competitive-inhibition calibration curve from below 2.5 mg/L to above 200 mg/L, provided good assay linearity (between 1.6 and 208.7 mg/L for κ FLC and between 3.5 and 249.7 mg/L for λ FLC) and sensitivity (1.4 mg/L for κ FLC and 1.7 mg/L for λ FLC), and eliminated anomalous results from antigen-excess. Seralite® gave good diagnostic concordance with Freelite® (Roche Hitachi Cobas C501) identifying an abnormal FLC ratio and FLC difference in 209 patients with newly diagnosed MM and differentiating these patients from normal healthy donors with polyclonal FLC. CONCLUSIONS: Seralite® sensitively quantitates FLC and rapidly identifies clinical conditions where FLC are abnormal, including MM.

Exploring the Measurement of Markedness and Its Relationship with Other Linguistic Variables.

Antonym pair members can be differentiated by each word's markedness-that distinction attributable to the presence or absence of features at morphological or semantic levels. Morphologically marked words incorporate their unmarked counterpart with additional morphs (e.g., "unlucky" vs. "lucky"); properties used to determine semantically marked words (e.g., "short" vs. "long") are less clearly defined. Despite extensive theoretical scrutiny, the lexical properties of markedness have received scant empirical study. The current paper employs an antonym sequencing approach to measure markedness: establishing markedness probabilities for individual words and evaluating their relationship with other lexical properties (e.g., length, frequency, valence). Regression analyses reveal that markedness probability is, as predicted, related to affixation and also strongly related to valence. Our results support the suggestion that antonym sequence is reflected in discourse, and further analysis demonstrates that markedness probabilities, derived from the antonym sequencing task, reflect the ordering of antonyms within natural language. In line with the Pollyanna Hypothesis, we argue that markedness is closely related to valence; language users demonstrate a tendency to present words evaluated positively ahead of those evaluated negatively if given the choice. Future research should consider the relationship of markedness and valence, and the influence of contextual information in determining which member of an antonym pair is marked or unmarked within discourse.