Green finance growth prediction model based on time-series conditional generative adversarial networks.

Climate change mitigation necessitates increased investment in green sectors. This study proposes a methodology to predict green finance growth across various countries, aiming to encourage such investments. Our approach leverages time-series Conditional Generative Adversarial Networks (CT-GANs) for data augmentation and Nonlinear Autoregressive Neural Networks (NARNNs) for prediction. The green finance growth predicting model was applied to datasets collected from forty countries across five continents. The Augmented Dickey-Fuller (ADF) test confirmed the non-stationary nature of the data, supporting the use of Nonlinear Autoregressive Neural Networks (NARNNs). CT-GANs were then employed to augment the data for improved prediction accuracy. Results demonstrate the effectiveness of the proposed model. NARNNs trained with CT-GAN augmented data achieved superior performance across all regions, with R-squared (R2) values of 98.8%, 96.6%, and 99% for Europe, Asia, and other countries respectively. While the RMSE for Europe, Asia, and other countries are 1.26e+2, 2.16e+2, and 1.16e+2 respectively. Compared to a baseline NARNN model without augmentation, CT-GAN augmentation significantly improved both R2 and RMSE. The R2 values for the Europe, Asia, and other countries models are 96%, 73%, and 97.2%, respectively. The RMSE values for the Europe, Asia, and various countries models are 2.24e+2, 7e+2, and 2.07e+2, respectively. The Nonlinear Autoregressive Exogenous Neural Network (NARX-NN) exhibited significantly lower performance across Europe, Asia, and other countries with R2 values of 74%, 52%, and 86%, and RMSE values of 1.11e+2, 3.63e+2, and 1.8e+2, respectively.

Intelligent and sustainable waste classification model based on multi-objective beluga whale optimization and deep learning.

Resource recycling is considered necessary for sustainable development, especially in smart cities where increased urbanization and the variety of waste generated require the development of automated waste management models. The development of smart technology offers a possible alternative to traditional waste management techniques that are proving insufficient to reduce the harmful effects of trash on the environment. This paper proposes an intelligent waste classification model to enhance the classification of waste materials, focusing on the critical aspect of waste classification. The proposed model leverages the InceptionV3 deep learning architecture, augmented by multi-objective beluga whale optimization (MBWO) for hyperparameter optimization. In MBWO, sensitivity and specificity evaluation criteria are integrated linearly as the objective function to find the optimal values of the dropout period, learning rate, and batch size. A benchmark dataset, namely TrashNet is adopted to verify the proposed model's performance. By strategically integrating MBWO, the model achieves a considerable increase in accuracy and efficiency in identifying waste materials, contributing to more effective waste management strategies while encouraging sustainable waste management practices. The proposed intelligent waste classification model outperformed the state-of-the-art models with an accuracy of 97.75%, specificity of 99.55%, F1-score of 97.58%, and sensitivity of 98.88%.

Circulating miRNA's biomarkers for early detection of hepatocellular carcinoma in Egyptian patients based on machine learning algorithms.

Liver cancer, which ranks sixth globally and third in cancer-related deaths, is caused by chronic liver disorders and a variety of risk factors. Despite therapeutic improvements, the prognosis for Hepatocellular Carcinoma (HCC) remains poor, with a 5-year survival rate for advanced cases of less than 12%. Although there is a noticeable decrease in the frequency of cases, liver cancer remains a significant worldwide health concern, with estimates surpassing one million cases by 2025. The prevalence of HCC has increased in Egypt, and it includes several neoplasms with distinctive messenger RNA (mRNA) and microRNA (miRNA) expression profiles. In HCC patients, certain miRNAs, such as miRNA-483-5P and miRNA-21, are upregulated, whereas miRNA-155 is elevated in HCV-infected people, encouraging hepatocyte proliferation. Short noncoding RNAs called miRNAs in circulation have the potential as HCC diagnostic and prognostic markers. This paper proposed a model for examining circulating miRNAs as diagnostic and predictive markers for HCC in Egyptian patients and their clinical and pathological characteristics. The proposed HCC detection model consists of three main phases: data preprocessing phase, feature selection based on the proposed Binary African Vulture Optimization Algorithm (BAVO) phase, and finally, classification as well as cross-validation phase. The first phase namely the data preprocessing phase tackle the main problems associated with the adopted datasets. In the feature selection based on the proposed BAVO algorithm phase, a new binary version of the BAVO swarm-based algorithm is introduced to select the relevant markers for HCC. Finally, in the last phase, namely the classification and cross-validation phase, the support vector machine and k-folds cross-validation method are utilized. The proposed model is evaluated on three studies on Egyptians who had HCC. A comparison between the proposed model and traditional statistical studies is reported to demonstrate the superiority of using the machine learning model for evaluating circulating miRNAs as diagnostic markers of HCC. The specificity and sensitivity for differentiation of HCC cases in comparison with the statistical-based method for the first study were 98% against 88% and 99% versus 92%, respectively. The second study revealed the sensitivity and specificity were 97.78% against 90% and 98.89% versus 92.5%, respectively. The third study reported 83.2% against 88.8% and 95.80% versus 92.4%, respectively. Additionally, the results show that circulating miRNA-483-5p, 21, and 155 may be potential new prognostic and early diagnostic biomarkers for HCC.

Harnessing machine learning to find synergistic combinations for FDA-approved cancer drugs.

Combination therapy is a fundamental strategy in cancer chemotherapy. It involves administering two or more anti-cancer agents to increase efficacy and overcome multidrug resistance compared to monotherapy. However, drug combinations can exhibit synergy, additivity, or antagonism. This study presents a machine learning framework to classify and predict cancer drug combinations. The framework utilizes several key steps including data collection and annotation from the O'Neil drug interaction dataset, data preprocessing, stratified splitting into training and test sets, construction and evaluation of classification models to categorize combinations as synergistic, additive, or antagonistic, application of regression models to predict combination sensitivity scores for enhanced predictions compared to prior work, and the last step is examination of drug features and mechanisms of action to understand synergy behaviors for optimal combinations. The models identified combination pairs most likely to synergize against different cancers. Kinase inhibitors combined with mTOR inhibitors, DNA damage-inducing drugs or HDAC inhibitors showed benefit, particularly for ovarian, melanoma, prostate, lung and colorectal carcinomas. Analysis highlighted Gemcitabine, MK-8776 and AZD1775 as frequently synergizing across cancer types. This machine learning framework provides a valuable approach to uncover more effective multi-drug regimens.

Insight into Automatic Image Diagnosis of Ear Conditions Based on Optimized Deep Learning Approach.

Examining otoscopic images for ear diseases is necessary when the clinical diagnosis of ear diseases extracted from the knowledge of otolaryngologists is limited. Improved diagnosis approaches based on otoscopic image processing are urgently needed. Recently, convolutional neural networks (CNNs) have been carried out for medical diagnosis to obtain higher accuracy than standard machine learning algorithms and specialists' expertise. Therefore, the proposed approach involves using the Bayesian hyperparameter optimization with the CNN architecture for automatic diagnosis of ear imagery database including four classes: normal, myringosclerosis, earwax plug, and chronic otitis media (COM). The suggested approach was trained using 616 otoscopic images, and the performance of this approach was assessed using 264 testing images. In this paper, the performance of ear disease classification was compared in terms of accuracy, sensitivity, specificity, and positive predictive value (PPV). The results produced a classification accuracy of 98.10%, a sensitivity of 98.11%, a specificity of 99.36%, and a PPV of 98.10%. Finally, the suggested approach demonstrates how to locate optimal CNN hyperparameters for accurate diagnosis of ear diseases while taking time into account. As a result, the usefulness and dependability of the suggested approach will lead to the establishment of an automated tool for better categorization and prediction of different ear diseases.

A multi-task learning model for predicting drugs combination synergy by analyzing drug-drug interactions and integrated multi-view graph data.

This paper proposes a multi-task deep learning model for determining drug combination synergistic by simultaneously output synergy scores and synergy class labels. Initially, the two drugs are represented using a Simplified Molecular-Input Line-Entry (SMILE) system. Chemical structural features of the drugs are extracted from the SMILE using the RedKit package. Additionally, an improved Multi-view representation is proposed to extract graph-based drug features. Furthermore, the cancer cell line is represented by gene expression. Then, a three fully connected layers are learned to extract cancer cell line features. To investigate the impact of drug interactions on cell lines, the drug interaction features are extracted from a pretrained drugs interaction network and fed into an attention mechanism along with the cancer cell line features, resulting in the output of affected cancer cell line features. Subsequently, the drug and cell line features are concatenated and fed into an attention mechanism, which produces a two-feature representation for the two predicted tasks. The relationship between the two tasks is learned using the cross-stitch algorithm. Finally, each task feature is inputted into a fully connected subnetwork to predict the synergy score and synergy label. The proposed model 'MutliSyn' is evaluated using the O'Neil cancer dataset, comprising 38 unique drugs combined to form 22,737 drug combination pairs, tested on 39 cancer cell lines. For the synergy score, the model achieves a mean square error (MSE) of 219.14, a root mean square error (RMSE) of 14.75, and a Pearson score of 0.76. Regarding the synergy class label, the model achieves an area under the ROC curve (ROC-AUC) of 0.95, an area under the precision-recall curve (PR-AUC) of 0.85, precision of 0.93, kappa of 0.61, and accuracy of 0.90.

A deep learning predictive model for public health concerns and hesitancy toward the COVID-19 vaccines.

Throughout the pandemic era, COVID-19 was one of the remarkable unexpected situations over the past few years, but with the decentralization and globalization of efforts and knowledge, a successful vaccine-based control strategy was efficiently designed and applied worldwide. On the other hand, excused confusion and hesitation have widely impacted public health. This paper aims to reduce COVID-19 vaccine hesitancy taking into consideration the patient's medical history. The dataset used in this study is the Vaccine Adverse Event Reporting System (VAERS) dataset which was created as a corporation between the Food and Drug Administration (FDA) and Centers for Disease Control and Prevention (CDC) to gather reported side effects that may be caused by PFIEZER, JANSSEN, and MODERNA vaccines. In this paper, a Deep Learning (DL) model has been developed to identify the relationship between a certain type of COVID-19 vaccine (i.e. PFIEZER, JANSSEN, and MODERNA) and the adverse reactions that may occur in vaccinated patients. The adverse reactions under study are the recovery condition, possibility to be hospitalized, and death status. In the first phase of the proposed model, the dataset has been pre-proceesed, while in the second phase, the Pigeon swarm optimization algorithm is used to optimally select the most promising features that affect the performance of the proposed model. The patient's status after vaccination dataset is grouped into three target classes (Death, Hospitalized, and Recovered). In the third phase, Recurrent Neural Network (RNN) is implemented for both each vaccine type and each target class. The results show that the proposed model gives the highest accuracy scores which are 96.031% for the Death target class in the case of PFIEZER vaccination. While in JANSSEN vaccination, the Hospitalized target class has shown the highest performance with an accuracy of 94.7%. Finally, the model has the best performance for the Recovered target class in MODERNA vaccination with an accuracy of 97.794%. Based on the accuracy and the Wilcoxon Signed Rank test, we can conclude that the proposed model is promising for identifying the relationship between the side effects of COVID-19 vaccines and the patient's status after vaccination. The study displayed that certain side effects were increased in patients according to the type of COVID-19 vaccines. Side effects related to CNS and hemopoietic systems demonstrated high values in all studied COVID-19 vaccines. In the frame of precision medicine, these findings can support the medical staff to select the best COVID-19 vaccine based on the medical history of the patient.

Retraction Note: Hybrid intelligent model for classifying chest X-ray images of COVID-19 patients using genetic algorithm and neutrosophic logic.

[This retracts the article DOI: 10.1007/s00500-021-06103-7.].

Pattern and predictors of death from aluminum and zinc phosphide poisoning using multi-kernel optimized relevance vector machine.

The use of metal phosphides, particularly aluminum phosphide, poses a significant threat to human safety and results in high mortality rates. This study aimed to determine mortality patterns and predictive factors for acute zinc and aluminum phosphide poisoning cases that were admitted to Menoufia University Poison and Dependence Control Center from 2017 to 2021. Statistical analysis revealed that poisoning was more common among females (59.7%), aged between 10 and 20 years, and from rural regions. Most cases were students, and most poisonings were the result of suicidal intentions (78.6%). A new hybrid model named Bayesian Optimization-Relevance Vector Machine (BO-RVM) was proposed to forecast fatal poisoning. The model achieved an overall accuracy of 97%, with high positive predictive value (PPV) and negative predictive value (NPV) values of 100% and 96%, respectively. The sensitivity was 89.3%, while the specificity was 100%. The F1 score was 94.3%, indicating a good balance between precision and recall. These results suggest that the model performs well in identifying both positive and negative cases. Additionally, the BO-RVM model has a fast and accurate processing time of 379.9595 s, making it a promising tool for various applications. The study underscores the need for public health policies to restrict the availability and use of phosphides in Egypt and adopt effective treatment methods for phosphide-poisoned patients. Clinical suspicion, positive silver nitrate test for phosphine, and analysis of cholinesterase levels are useful in diagnosing metal phosphide poisoning, which can cause various symptoms.

Many-objective African vulture optimization algorithm: A novel approach for many-objective problems.

Several optimization problems can be abstracted into many-objective optimization problems (MaOPs). The key to solving MaOPs is designing an effective algorithm to balance the exploration and exploitation issues. This paper proposes a novel many-objective African vulture optimization algorithm (MaAVOA) that simulating the African vultures' foraging and navigation behaviours to solve the MaOPs. MaAVOA is an updated version of the African Vulture Optimization Algorithm (AVOA), which was recently proposed to solve the MaOPs. A new social leader vulture for the selection process is introduced and integrated into the proposed model. In addition, an environmental selection mechanism based on the alternative pool is adapted to improve the selection process to maintain diversity for approximating different parts of the whole Pareto Front (PF). The best-nondominated solutions are saved in an external Archive based on the Fitness Assignment Method (FAM) during the population evolution. FAM is based on a convergence measure that promotes convergence and a density measure that promotes variety. Also, a Reproduction of Archive Solutions (RAS) procedure is developed to improve the quality of archiving solutions. RAS has been designed to help reach out to the missing areas of the PF that the vultures easily miss. Two experiments are conducted to verify and validate the suggested MaAVOA's performance efficacy. First, MaAVOA was applied to the DTLZ functions, and its performance was compared to that of several popular many-objective algorithms and according to the results, MaAVOA outperforms the competitor algorithms in terms of inverted generational distance and hypervolume performance measures and has a beneficial adaptation ability in terms of both convergence and diversity performance measures. Also, statistical tests are implemented to demonstrate the suggested algorithm's statistical relevance. Second, MaAVOA has been applied to solve two real-life constrained engineering MaOPs applications, namely, the series-parallel system and overspeed protection for gas turbine problems. The experiments show that the suggested algorithm can tackle many-objective real-world applications and provide promising choices for decision-makers.

An Optimized Ensemble Deep Learning Model for Predicting Plant miRNA-IncRNA Based on Artificial Gorilla Troops Algorithm.

MicroRNAs (miRNA) are small, non-coding regulatory molecules whose effective alteration might result in abnormal gene manifestation in the downstream pathway of their target. miRNA gene variants can impact miRNA transcription, maturation, or target selectivity, impairing their usefulness in plant growth and stress responses. Simple Sequence Repeat (SSR) based on miRNA is a newly introduced functional marker that has recently been used in plant breeding. MicroRNA and long non-coding RNA (lncRNA) are two examples of non-coding RNA (ncRNA) that play a vital role in controlling the biological processes of animals and plants. According to recent studies, the major objective for decoding their functional activities is predicting the relationship between lncRNA and miRNA. Traditional feature-based classification systems' prediction accuracy and reliability are frequently harmed because of the small data size, human factors' limits, and huge quantity of noise. This paper proposes an optimized deep learning model built with Independently Recurrent Neural Networks (IndRNNs) and Convolutional Neural Networks (CNNs) to predict the interaction in plants between lncRNA and miRNA. The deep learning ensemble model automatically investigates the function characteristics of genetic sequences. The proposed model's main advantage is the enhanced accuracy in plant miRNA-IncRNA prediction due to optimal hyperparameter tuning, which is performed by the artificial Gorilla Troops Algorithm and the proposed intelligent preying algorithm. IndRNN is adapted to derive the representation of learned sequence dependencies and sequence features by overcoming the inaccuracies of natural factors in traditional feature architecture. Working with large-scale data, the suggested model outperforms the current deep learning model and shallow machine learning, notably for extended sequences, according to the findings of the experiments, where we obtained an accuracy of 97.7% in the proposed method.

A hybrid equilibrium algorithm and pattern search technique for wind farm layout optimization problem.

The layout optimization-based model is a significant issue for increasing the utilization rate of the wind farm and minimizing its cost per unit of power. For the accurate and reliable wind farm layout optimization design, a novel algorithm based on the hybridization of equilibrium optimizer (EO) and pattern search (PS) technique, named EO-PS, is proposed in this paper. The proposed EO-PS operates in two phases. The first phase implements the EO to explore the search space and reach the promising regions by using an equilibrium pool of elite particles, which contributes to maintaining the diversity of solutions. The second phase integrates the PS to guide the searching towards better vicinities and achieve a high-quality solution by using its detecting and pattern movements to boost the exploitation ability of the proposed method in the last steps. The presented EO-PS algorithm is implemented to deal with single and multi-objective optimization aspects of wind farm layout optimization using different wind speed scenarios. Furthermore, the proposed algorithm is investigated on irregular land space in the Gulf of Suez-Red Sea in Egypt to achieve the optimal layout configuration of the wind farm, which is vital for possible practical planning trends. The comprehensive results and analyses have affirmed that the proposed EO-PS can achieve competitive performance compared to the other state-of-the-state methods, especially in terms of the solution' quality and reliability.

Hybrid intelligent model for classifying chest X-ray images of COVID-19 patients using genetic algorithm and neutrosophic logic.

The highly spreading virus, COVID-19, created a huge need for an accurate and speedy diagnosis method. The famous RT-PCR test is costly and not available for many suspected cases. This article proposes a neurotrophic model to diagnose COVID-19 patients based on their chest X-ray images. The proposed model has five main phases. First, the speeded up robust features (SURF) method is applied to each X-ray image to extract robust invariant features. Second, three sampling algorithms are applied to treat imbalanced dataset. Third, the neutrosophic rule-based classification system is proposed to generate a set of rules based on the three neutrosophic values < T; I; F>, the degrees of truth, indeterminacy falsity. Fourth, a genetic algorithm is applied to select the optimal neutrosophic rules to improve the classification performance. Fifth, in this phase, the classification-based neutrosophic logic is proposed. The testing rule matrix is constructed with no class label, and the goal of this phase is to determine the class label for each testing rule using intersection percentage between testing and training rules. The proposed model is referred to as GNRCS. It is compared with six state-of-the-art classifiers such as multilayer perceptron (MLP), support vector machines (SVM), linear discriminant analysis (LDA), decision tree (DT), naive Bayes (NB), and random forest classifiers (RFC) with quality measures of accuracy, precision, sensitivity, specificity, and F1-score. The results show that the proposed model is powerful for COVID-19 recognition with high specificity and high sensitivity and less computational complexity. Therefore, the proposed GNRCS model could be used for real-time automatic early recognition of COVID-19.

A pre-trained convolutional neural network with optimized capsule networks for chest X-rays COVID-19 diagnosis.

Coronavirus disease (COVID-19) is rapidly spreading worldwide. Recent studies show that radiological images contain accurate data for detecting the coronavirus. This paper proposes a pre-trained convolutional neural network (VGG16) with Capsule Neural Networks (CapsNet) to detect COVID-19 with unbalanced data sets. The CapsNet is proposed due to its ability to define features such as perspective, orientation, and size. Synthetic Minority Over-sampling Technique (SMOTE) was employed to ensure that new samples were generated close to the sample center, avoiding the production of outliers or changes in data distribution. As the results may change by changing capsule network parameters (Capsule dimensionality and routing number), the Gaussian optimization method has been used to optimize these parameters. Four experiments have been done, (1) CapsNet with the unbalanced data sets, (2) CapsNet with balanced data sets based on class weight, (3) CapsNet with balanced data sets based on SMOTE, and (4) CapsNet hyperparameters optimization with balanced data sets based on SMOTE. The performance has improved and achieved an accuracy rate of 96.58% and an F1- score of 97.08%, a competitive optimized model compared to other related models.

Deep learning in drug discovery: an integrative review and future challenges.

Recently, using artificial intelligence (AI) in drug discovery has received much attention since it significantly shortens the time and cost of developing new drugs. Deep learning (DL)-based approaches are increasingly being used in all stages of drug development as DL technology advances, and drug-related data grows. Therefore, this paper presents a systematic Literature review (SLR) that integrates the recent DL technologies and applications in drug discovery Including, drug-target interactions (DTIs), drug-drug similarity interactions (DDIs), drug sensitivity and responsiveness, and drug-side effect predictions. We present a review of more than 300 articles between 2000 and 2022. The benchmark data sets, the databases, and the evaluation measures are also presented. In addition, this paper provides an overview of how explainable AI (XAI) supports drug discovery problems. The drug dosing optimization and success stories are discussed as well. Finally, digital twining (DT) and open issues are suggested as future research challenges for drug discovery problems. Challenges to be addressed, future research directions are identified, and an extensive bibliography is also included.

Deep neural network prediction of modified stepped double-slope solar still with a cotton wick and cobalt oxide nanofluid.

This research work intends to enhance the stepped double-slope solar still performance through an experimental assessment of combining linen wicks and cobalt oxide nanoparticles to the stepped double-slope solar still to improve the water evaporation and water production. The results illustrated that the cotton wicks and cobalt oxide (Co3O4) nanofluid with 1wt% increased the hourly freshwater output (HP) and instantaneous thermal efficiency (ITE). On the other hand, this study compares four machine learning methods to create a prediction model of tubular solar still performance. The methods developed and compared are support vector regressor (SVR), decision tree regressor, neural network, and deep neural network based on experimental data. This problem is a multi-output prediction problem which is HP and ITE. The prediction performance for the SVR was the lowest, with 70 (ml/m2 h) mean absolute error (MAE) for HP and 4.5% for ITE. Decision tree regressor has a better prediction for HP with 33 (ml/m2 h) MAE and almost the same MAE for ITE. Neural network has a better prediction for HP with 28 (ml/m2 h) MAE and a bit worse prediction for ITE with 5.7%. The best model used the deep neural network with 1.94 (ml/m2 h) MAE for HP and 0.67% MAE for ITE.

Classification of Ear Imagery Database using Bayesian Optimization based on CNN-LSTM Architecture.

The external and middle ear conditions are diagnosed using a digital otoscope. The clinical diagnosis of ear conditions is suffered from restricted accuracy due to the increased dependency on otolaryngologist expertise, patient complaint, blurring of the otoscopic images, and complexity of lesions definition. There is a high requirement for improved diagnosis algorithms based on otoscopic image processing. This paper presented an ear diagnosis approach based on a convolutional neural network (CNN) as feature extraction and long short-term memory (LSTM) as a classifier algorithm. However, the suggested LSTM model accuracy may be decreased by the omission of a hyperparameter tuning process. Therefore, Bayesian optimization is used for selecting the hyperparameters to improve the results of the LSTM network to obtain a good classification. This study is based on an ear imagery database that consists of four categories: normal, myringosclerosis, earwax plug, and chronic otitis media (COM). This study used 880 otoscopic images divided into 792 training images and 88 testing images to evaluate the approach performance. In this paper, the evaluation metrics of ear condition classification are based on a percentage of accuracy, sensitivity, specificity, and positive predictive value (PPV). The findings yielded a classification accuracy of 100%, a sensitivity of 100%, a specificity of 100%, and a PPV of 100% for the testing database. Finally, the proposed approach shows how to find the best hyperparameters concerning the Bayesian optimization for reliable diagnosis of ear conditions under the consideration of LSTM architecture. This approach demonstrates that CNN-LSTM has higher performance and lower training time than CNN, which has not been used in previous studies for classifying ear diseases. Consequently, the usefulness and reliability of the proposed approach will create an automatic tool for improving the classification and prediction of various ear pathologies.

Genetic-based adaptive momentum estimation for predicting mortality risk factors for COVID-19 patients using deep learning.

The mortality risk factors for coronavirus disease (COVID-19) must be early predicted, especially for severe cases, to provide intensive care before they develop to critically ill immediately. This paper aims to develop an optimized convolution neural network (CNN) for predicting mortality risk factors for COVID-19 patients. The proposed model supports two types of input data clinical variables and the computed tomography (CT) scans. The features are extracted from the optimized CNN phase and then applied to the classification phase. The CNN model's hyperparameters were optimized using a proposed genetic-based adaptive momentum estimation (GB-ADAM) algorithm. The GB-ADAM algorithm employs the genetic algorithm (GA) to optimize Adam optimizer's configuration parameters, consequently improving the classification accuracy. The model is validated using three recent cohorts from New York, Mexico, and Wuhan, consisting of 3055, 7497,504 patients, respectively. The results indicated that the most significant mortality risk factors are: CD 8 + T Lymphocyte (Count), D-dimer greater than 1 Ug/ml, high values of lactate dehydrogenase (LDH), C-reactive protein (CRP), hypertension, and diabetes. Early identification of these factors would help the clinicians in providing immediate care. The results also show that the most frequent COVID-19 signs in CT scans included ground-glass opacity (GGO), followed by crazy-paving pattern, consolidations, and the number of lobes. Moreover, the experimental results show encouraging performance for the proposed model compared with different predicting models.

Chaos-opposition-enhanced slime mould algorithm for minimizing the cost of energy for the wind turbines on high-altitude sites.

This paper presents a chaos-opposition-enhanced slime mould algorithm (CO-SMA) to minimize energy (COE) cost for the wind turbines on high-altitude sites. The COE model is established based on rotor radius, rated power, and hub height needed to achieve an optimal design model. In this context, an improved variant of SMA, named CO-SMA, is proposed based on a chaotic search strategy (CSS) and crossover-opposition strategy (COS) to cope with the potential weaknesses classical SMA while dealing with nonlinear tasks. First, the COS is introduced to enhance the diversity of solutions and thus improves the exploratory tendencies. The CSS is incorporated into the basic SMA to improve the exploitative abilities and thus avoids the premature convergence dilemma. The proposed CO-SMA is validated on the design of wind turbines with high-altitude sites. Furthermore, the sensitivity analysis based on the Taguchi method is developed to exhibit the impact of the COE model's optimized parameters. The influence of uncertainty based on the fuzziness scheme of wind resource statistics is also explored to depict a real scheme for the changes that occurred by seasonal time, atmospheric conditions, and topographic conditions. The proposed CO-SMA is compared with the PSO, WOA, GWO, MDWA, and SMA, where the COE values are recorded as 0.052408, 0.052462, 0.052435, 0.052409, 0.052413, and 0.052915, respectively. Furthermore, the proposed CO-SMA records the faster convergence than the others. On the other hand, the Taguchi method reveals that the rated power is the most significant parameter on the COE model. Also, the impact of the fuzziness scheme on COE is exhibited, where the increasing interval of vagueness can increase the value of COE.

A novel melanoma prediction model for imbalanced data using optimized SqueezeNet by bald eagle search optimization.

Skin lesion classification plays a crucial role in diagnosing various gene and related local medical cases in the field of dermoscopy. In this paper, a new model for the classification of skin lesions as either normal or melanoma is presented. The proposed melanoma prediction model was evaluated on a large publicly available dataset called ISIC 2020. The main challenge of this dataset is severe class imbalance. This paper proposes an approach to overcome this problem using a random over-sampling method followed by data augmentation. Moreover, a new hybrid version of a convolutional neural network architecture and bald eagle search (BES) optimization is proposed. The BES algorithm is used to find the optimal values of the hyperparameters of a SqueezeNet architecture. The proposed melanoma skin cancer prediction model obtained an overall accuracy of 98.37%, specificity of 96.47%, sensitivity of 100%, f-score of 98.40%, and area under the curve of 99%. The experimental results showed the robustness and efficiency of the proposed model compared with VGG19, GoogleNet, and ResNet50. Additionally, the results showed that the proposed model was very competitive compared with the state of the art.