Machine Learning Models for Predicting Disability and Pain Following Lumbar Disc Herniation Surgery.

Importance: Lumber disc herniation surgery can reduce pain and disability. However, a sizable minority of individuals experience minimal benefit, necessitating the development of accurate prediction models. Objective: To develop and validate prediction models for disability and pain 12 months after lumbar disc herniation surgery. Design, Setting, and Participants: A prospective, multicenter, registry-based prognostic study was conducted on a cohort of individuals undergoing lumbar disc herniation surgery from January 1, 2007, to May 31, 2021. Patients in the Norwegian Registry for Spine Surgery from all public and private hospitals in Norway performing spine surgery were included. Data analysis was performed from January to June 2023. Exposures: Microdiscectomy or open discectomy. Main Outcomes and Measures: Treatment success at 12 months, defined as improvement in Oswestry Disability Index (ODI) of 22 points or more; Numeric Rating Scale (NRS) back pain improvement of 2 or more points, and NRS leg pain improvement of 4 or more points. Machine learning models were trained for model development and internal-external cross-validation applied over geographic regions to validate the models. Model performance was assessed through discrimination (C statistic) and calibration (slope and intercept). Results: Analysis included 22 707 surgical cases (21 161 patients) (ODI model) (mean [SD] age, 47.0 [14.0] years; 12 952 [57.0%] males). Treatment nonsuccess was experienced by 33% (ODI), 27% (NRS back pain), and 31% (NRS leg pain) of the patients. In internal-external cross-validation, the selected machine learning models showed consistent discrimination and calibration across all 5 regions. The C statistic ranged from 0.81 to 0.84 (pooled random-effects meta-analysis estimate, 0.82; 95% CI, 0.81-0.84) for the ODI model. Calibration slopes (point estimates, 0.94-1.03; pooled estimate, 0.99; 95% CI, 0.93-1.06) and calibration intercepts (point estimates, -0.05 to 0.11; pooled estimate, 0.01; 95% CI, -0.07 to 0.10) were also consistent across regions. For NRS back pain, the C statistic ranged from 0.75 to 0.80 (pooled estimate, 0.77; 95% CI, 0.75-0.79); for NRS leg pain, the C statistic ranged from 0.74 to 0.77 (pooled estimate, 0.75; 95% CI, 0.74-0.76). Only minor heterogeneity was found in calibration slopes and intercepts. Conclusion: The findings of this study suggest that the models developed can inform patients and clinicians about individual prognosis and aid in surgical decision-making.

Quality of Monitoring Optimization in Underwater Sensor Networks through a Multiagent Diversity-Based Gradient Approach.

Due to the complex underwater environment, conventional measurement and sensing methods used for land are difficult to apply directly in the underwater environment. Especially for seabed topography, it is impossible to perform long-distance and accurate detection by electromagnetic waves. Therefore, various types of acoustic and even optical sensing devices for underwater applications have been used. Equipped with submersibles, these underwater sensors can detect a wide underwater range accurately. In addition, the development of sensor technology will be modified and optimized according to the needs of ocean exploitation. In this paper, we propose a multiagent approach for optimizing the quality of monitoring (QoM) in underwater sensor networks. Our framework aspires to optimize the QoM by resorting to the machine learning concept of diversity. We devise a multiagent optimization procedure which is able to both reduce the redundancy among the sensor readings and maximize the diversity in a distributed and adaptive manner. The mobile sensor positions are adjusted iteratively using a gradient type of updates. The overall framework is tested through simulations based on realistic environment conditions. The proposed approach is compared to other placement approaches and is found to achieve a higher QoM with a smaller number of sensors.

Tuning of Elasticsearch Configuration: Parameter Optimization Through Simultaneous Perturbation Stochastic Approximation.

Elasticsearch is currently the most popular search engine for full-text database management systems. By default, its configuration does not change while it receives data. However, when Elasticsearch stores a large amount of data over time, the default configuration becomes an obstacle to improving performance. In addition, the servers that host Elasticsearch may have limited resources, such as internal memory and CPU. A general solution to these problems is to dynamically tune the configuration parameters of Elasticsearch in order to improve its performance. The sheer number of parameters involved in this configuration makes it a complex task. In this work, we apply the Simultaneous Perturbation Stochastic Approximation method for optimizing Elasticsearch with multiple unknown parameters. Using this algorithm, our implementation optimizes the Elasticsearch configuration parameters by observing the performance and automatically changing the configuration to improve performance. The proposed solution makes it possible to change the configuration parameters of Elasticsearch automatically without having to restart the currently running instance of Elasticsearch. The results show a higher than 40% improvement in the combined data insertion capacity and the system's response time.