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1.
Phys Sportsmed ; 51(6): 549-557, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-36373406

RESUMO

Exercise-induced bronchoconstriction (EIB) is the most common chronic disease among elite athletes and when left untreated, can impact both respiratory health and sports performance. In recent years, there has been an increase in the awareness and detection of EIB in elite athletes. This narrative review aims to evaluate the risk, prevention, diagnosis, medication, and anti-doping policies of EIB in elite athletes, and to provide more references for athletes with EIB. The results showed that athletes of endurance, winter, and water sports generally have a higher prevalence of EIB than athletes of other sports. Adaptive warm-up before formal exercise and using heat exchange masks at low temperatures are effective ways for athletes to prevent EIB. For physicians, the exercise challenge test and eucapnic voluntary hyperpnea are the recommended diagnostic methods for EIB in athletes. The treatment of athletes with EIB is medication-based, such as inhaled corticosteroids and beta-2 agonists, but current anti-doping policies should be considered when used.


Assuntos
Asma Induzida por Exercício , Desempenho Atlético , Humanos , Broncoconstrição , Asma Induzida por Exercício/diagnóstico , Asma Induzida por Exercício/epidemiologia , Asma Induzida por Exercício/terapia , Atletas , Testes de Provocação Brônquica
2.
Comput Intell Neurosci ; 2021: 2324352, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34824575

RESUMO

Based on video, the human movement can be analyzed to achieve scientific training and skill improvement. Specifically, according to the video data during the movement, the human body can be detected and tracked, and relevant trajectory data can be obtained. On this basis, key motion parameters can be obtained and quantitative analysis of motion can be achieved. This paper uses video processing technologies to analyze the long jump posture in physical education. According to the video sequences measured during the athlete's long jump, the target detection and tracking algorithms are used to obtain the athlete's trajectory after preprocessing. Afterwards, further processing is carried out to calculate speed, angle, posture, and other related information to assist scientific sports training. The experimental results based on the measured data show that the algorithm can realize the analysis of the long jump scene and complete the quantitative analysis of the key indicators of the athletes. The research results can effectively support school physical education and guidance training and also provide a reference for other competitive video analysis.


Assuntos
Educação Física e Treinamento , Esportes , Atletas , Humanos , Postura , Instituições Acadêmicas
3.
Fitoterapia ; 151: 104904, 2021 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-33813000

RESUMO

Five new compounds (xuejieins A-E), including three new phenolic glycosides (1, 2, and 5) and two new flavonoids (10 and 11), together with six known compounds were isolated from the resins of Dracaena cochinchinensis (Chinese dragon's blood). The structures of the new compounds were confirmed by extensive spectroscopic methods and electronic circular dichroism (ECD) data analysis. Especially, the absolute configurations of the sugar moieties in compounds 1, 2, and 5 were clarified by GC analysis after acid hydrolysis. All isolated compounds have been tested for antifungal and wound healing promoting activities, The results showed that compound 9 shows significant antifungal activities against Botrytis cinerea, Magnaporthe grisea, Penicillium digitatum, and Sclerotinia sclerotiorum. In addition, compound 4 could significantly stimulate human keratinocytes (HaCAT) proliferation, mobility, and human umbilical vein vascular endothelial cells (HUVECs) tube formation at 40 µM.


Assuntos
Antifúngicos/farmacologia , Dracaena/química , Resinas Vegetais/química , Cicatrização , Antifúngicos/isolamento & purificação , China , Flavonoides/isolamento & purificação , Flavonoides/farmacologia , Glicosídeos/isolamento & purificação , Glicosídeos/farmacologia , Células HaCaT , Células Endoteliais da Veia Umbilical Humana , Humanos , Estrutura Molecular , Compostos Fitoquímicos/isolamento & purificação , Compostos Fitoquímicos/farmacologia , Extratos Vegetais
4.
Fitoterapia ; 143: 104560, 2020 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-32199957

RESUMO

Five new terpenoids including one new abietane diterpenoid (1), one new aromadendrane diterpenoid (6), two new norsesquiterpenoids (8 and 9), and a new cembrane-derived diterpenoid (12), together with seven known compounds were isolated from Populus euphratica resins. The structures of these new compounds, including their absolute configurations, were characterized by spectroscopic and computational methods. All the compounds except 8 were test for their neuroprotective activities. The result revealed that compounds 1, 7, and 10-12 display neuroprotective activities in glutamate-induced SH-SY5Y cells in a concentration-dependent manner.


Assuntos
Fármacos Neuroprotetores/farmacologia , Populus/química , Resinas Vegetais/química , Terpenos/farmacologia , Abietanos , Linhagem Celular Tumoral , China , Diterpenos , Humanos , Estrutura Molecular , Fármacos Neuroprotetores/isolamento & purificação , Compostos Fitoquímicos/isolamento & purificação , Compostos Fitoquímicos/farmacologia , Sesquiterpenos , Terpenos/isolamento & purificação
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