Source Identification of Urban dust Heavy Metals Using in Situ and Satellite Data in Three Mega Cities of Iran.

The aim of this study was an integrative assessment of heavy metals associated with urban dust data in Iran (Ahvaz, Isfahan, and Shiraz). Samples of urban dust from four sites (traffic, industrial, residential, and Greenland) were collected, and ten heavy metal concentrations were determined using ICP_MS in each sample. The highest average concentrations of metals were at the traffic site for the Mn, Zn, and Cr metals. The PMF model indicates a higher percentage of Pb participation, which shows the importance of traffic resources. The highest non-carcinogenic risk (HI) was for the Cr and the carcinogenic risk was tolerable. To evaluate aerosol and its effects on urban dust, Aerosol Optical Depth (AOD) data were used during 2003-2023. According to the Mankendall test, the trend of AOD has been increasing in Esfahan (p_value < 0.05) and Shiraz. Although Ahvaz's AOD is about two times greater than other cities, the aerosol trend in Ahvaz is decreasing.

Integrative assessment of urban dust polycyclic aromatic hydrocarbons using ground and satellite data in Iran.

Recently, for quick urbanization and industrialization, pollutants, especially urban dust, have posed many threats to the human environment. Polycyclic aromatic hydrocarbons (PAHs) are regarded as the main dangerous pollutants that are widespread, persistent, and carcinogenic. The present work aimed to investigate the contamination and sources of PAHs, as well as to assess the risk of cancer for 16 priority PAHs, in urban dust samples in Ahvaz, Isfahan, and Shiraz cities in Iran. We measured PAH concentrations by gas chromatography-mass spectrometry (GC-MS). The average concentrations of the 16 PAHs in Ahvaz, Isfahan, and Shiraz were 6215.11, 7611.03, and 7810.37 µg kg-1, respectively. The domination of low-molecular-weight (LMW) PAHs was observed in Ahvaz, while maximum contribution was observed for high-molecular-weight (HMW) PAHs in Esfahan and Shiraz. For PAHs' source identification, diagnostic ratio, correlation analysis, clustering, and positive matrix factorization (PMF) model were used. PAHs had a combustion (coal and wood, oil, fossil fuels) and gasoline/diesel engine emissions in all cities. Comparative studies suggest that the PAH compounds' level is higher in the research area than in other countries, except for China and India. Also, the pollution of urban dust PAHs has increased over time compared to previous studies in the same cities. The cancer risk from exposure to dust contaminated with PAHs was assessed using the Incremental Lifetime Cancer Risk (ILCR) model. According to the findings, a high risk of exposure to cancer was observed in Ahvaz, Isfahan, and Shiraz. However, compared to adults, children are at higher risk of cancer in their daily lives via dermal contact and unconscious ingestion. Based on the ILCR values, the risk of cancer is in the order of Shiraz > Isfahan > Ahvaz. To assess air pollutants and their effects on urban dust, TROPOMI onboard the Sentinel-5P data were used in the studied cities during 2018-2021. The results show that Ahvaz has different high levels of CO compared to the other 2 cities. Also, Isfahan has different high levels of NO2 compared to the other 2 cities, but Shiraz has different low levels of O3. According to satellite time series data, the trend of the Aerosol Absorbing Index (AAI) has been increasing, while there was a decreasing trend in AAI from the beginning of the COVID-19 pandemic until 12 months later. Therefore, the natural and anthropogenic sources of urban dust PAHs have been increasing in all studied cities. Our findings show that PAH compounds in urban dust pose a significant threat to human health. Therefore, strategic management and planning are vital in reducing urban dust pollution.

Schottky graphene/Si photodetector based on metal-dielectric hybrid hollow-core photonic crystal fibers.

This Letter presents a new family of Schottky graphene/silicon (Si) photodetectors (PDs) based on hollow-core photonic crystal fibers (HPCFs), working at both optical communication and room temperature. The proposed structure has the advantage of plasmonic HPCFs in a slow-light regime, and the absorption mechanism is based on an internal photoemission effect. The main feature of this structure is that the enhanced electric field is strongly localized in the hollow core of the guided core mode with the surface plasmon modes at the surface metal wires embedded in the photonic crystal structure. For the proposed graphene/silicon Schottky PD, numerical simulation predicts responsivity of ∼0.39 A/W, and continuous-wave sensitivity of -59 dBm, which reveals substantial improvements compared to that of typical metal/Si Schottky PDs.

The effects of cognitively demanding dual-task driving condition on elderly people's driving performance; Real driving monitoring.

BACKGROUND: Using in-vehicle audio technologies such as audio systems and voice messages is regarded as a common secondary task. Such tasks, known as the sources of non-visual distraction, affect the driving performance. Given the elderly drivers' cognitive limitations, driving can be even more challenging to drivers. The current study examined how listening to economic news, as a cognitively demanding secondary task, affects elderly subjects' driving performance and whether their comprehension accuracy is associated with these effects. METHODS: Participants of the study (N=22) drove in a real condition with and without listening to economic news. Measurements included driving performance (speed control, forward crash risk, and lateral lane position) and task performance (comprehension accuracy). RESULTS: The mean driving speed, duration of driving in unsafe zones and numbers of overtaking decreased significantly when drivers were engaged in the dual-task condition. Moreover, the cognitive secondary task led to a higher speed variability. Our results demonstrate that there was not a significant relationship between the lane changes and the activity of listening to economic news. However, a meaningful difference was observed between general comprehension and deep comprehension on the one hand and driving performance on the other. Another aspect of our study concerning the drivers' ages and their comprehension revealed a significant relationship between age above 75 and comprehension level. Drivers aging 75 and older showed a lower level of deep comprehension. CONCLUSION: Our study demonstrates that elderly drivers compensated driving performance with safety margin adoption while they were cognitively engaged. In this condition, however, maintaining speed proved more demanding for drivers aging 75 and older.

Midinfrared supercontinuum generation via As2Se3 chalcogenide photonic crystal fibers.

Using numerical analysis, we compare the results of optofluidic and rod filling techniques for the broadening of supercontinuum spectra generated by As2Se3 chalcogenide photonic crystal fibers (PCFs). The numerical results show that when air-holes constituting the innermost ring in a PCF made of As2Se3-based chalcogenide glass are filled with rods of As2Se3-based chalcogenide glass, over a wide range of mid-IR wavelengths, an ultra-flattened near-zero dispersion can be obtained, while the total loss is negligible and the PCF nonlinearity is very high. The simulations also show that when a 50 fs input optical pulse of 10 kW peak power and center wavelength of 4.6 µm is launched into a 50 mm long rod-filled chalcogenide PCF, a ripple-free spectral broadening as wide as 3.86 µm can be obtained.

Design and numerical simulation of an optofluidic pressure sensor.

We present a numerical design procedure for an all-optical compact sensor by means of integrating the optofluidic switch polymer interferometers to measure the microfluidic air pressure and flow rate. The design is based on a flexible air gap optical cavity that can generate an interference pattern when illuminated by a monochromatic light. The optical interference pattern directly depends on the pressure. In our numerical simulations, we take the effects of fluid flow rate, solid deformation, and the light interference into account. We use the beam propagation method for simulating the optics and the finite element method for simulating the mechanics. The significance of the proposed sensor lies with its low power consumption, compactness, low cost, and short length. This sensor can operate under pressure range of 0-60±6% Pa at a constant temperature of 20 °C.

Design of an ultracompact low-power all-optical modulator by means of dispersion engineered slow light regime in a photonic crystal Mach-Zehnder interferometer.

We present the design procedure for an ultracompact low-power all-optical modulator based on a dispersion-engineered slow-light regime in a photonic crystal Mach-Zehnder interferometer (PhC MZI), selectively infiltrated by nonlinear optical fluids. The dispersionless slow-light regime enhancing the nonlinearities enabled a 22 µm long PhC MZI to operate as a modulator with an input power as low as 3 mW/µm. Simulations reveal that the switching threshold can be controlled by varying the optofluidic infiltration.

Proposal for enhancing the transmission efficiency of photonic crystal 60° waveguide bends by means of optofluidic infiltration.

We are proposing a procedure to enhance the transmission efficiency of 60° photonic crystal (PhC) waveguide bends by means of selective optofluidic infiltration of an air hole, which is created as a point defect at the center of the conventional 60° PhC bend. Numerical studies demonstrate that by varying the defect radius and indices of optical fluids, one may enhance the bend transmission level and tune its 3 dB bandwidth over a substantial range of 88-138 nm. In order to perform the numerical simulations, we have used two-dimensional (2D) finite difference time domain plane wave method, keeping in mind that the spectral features obtained by these 2D calculations are about 15% redshifted from those of real three-dimensional structures.

The relationship between cellular adhesion and surface roughness in polystyrene modified by microwave plasma radiation.

BACKGROUND: Surface modification of medical polymers can improve biocompatibility. Pure polystyrene is hydrophobic and cannot provide a suitable environment for cell cultures. The conventional method for surface modification of polystyrene is treatment with plasma. In this study, conventional polystyrene was exposed to microwave plasma treatment with oxygen and argon gases for 30, 60, and 180 seconds. METHODS AND RESULTS: Attenuated total reflection Fourier transform infrared spectra investigations of irradiated samples indicated clearly the presence of functional groups. Atomic force microscopic images of samples irradiated with inert and active gases indicated nanometric surface topography. Samples irradiated with oxygen plasma showed more roughness (31 nm) compared with those irradiated with inert plasma (16 nm) at 180 seconds. Surface roughness increased with increasing duration of exposure, which could be due to reduction of the contact angle of samples irradiated with oxygen plasma. Contact angle analysis showed reduction in samples irradiated with inert plasma. Samples irradiated with oxygen plasma showed a lower contact angle compared with those irradiated by argon plasma. CONCLUSION: Cellular investigations with unrestricted somatic stem cells showed better adhesion, cell growth, and proliferation for samples radiated by oxygen plasma with increasing duration of exposure than those of normal samples.

Swing effect of spatial solitons propagating through Gaussian and triangular waveguides.

We report the behavior of spatial optical solitons propagating through inhomogeneous waveguides with Gaussian, single triangular, and double-triangular refractive index profiles. In a given Gaussian profile, as the soliton amplitude decreases below a certain value, its behavior deviates from that of a particlelike soliton. Dependence of the swing period of a spatial soliton in a single triangular index profile on its amplitude, eta, is less significant than that in a Gaussian profile. We also report the interacting behavior of two solitons propagating simultaneously through a waveguide with a double-triangular index profile. Furthermore, we present the effects of the solitons' initial phase factors and amplitude on their behavior.

Slow light enhancement of nonlinear effects in silicon engineered photonic crystal waveguides.

We report nonlinear measurements on 80microm silicon photonic crystal waveguides that are designed to support dispersionless slow light with group velocities between c/20 and c/50. By launching picoseconds pulses into the waveguides and comparing their output spectral signatures, we show how self phase modulation induced spectral broadening is enhanced due to slow light. Comparison of the measurements and numerical simulations of the pulse propagation elucidates the contribution of the various effects that determine the output pulse shape and the waveguide transfer function. In particular, both experimental and simulated results highlight the significant role of two photon absorption and free carriers in the silicon waveguides and their reinforcement in the slow light regime.

Effect of the mechanical activation on size reduction of crystalline acetaminophen drug particles.

The decrease in particle size may offer new properties to drugs. In this study, we investigated the size reduction influence of the acetaminophen (C(8)H(9)O(2)N) particles by mechanical activation using a dry ball mill. The activated samples with the average size of 1 microm were then investigated in different time periods with the infrared (IR), inductively coupled plasma (ICP), atomic force microscopy (AFM), and X-ray diffraction (XRD) methods. The results of the IR and XRD images showed no change in the drug structure after the mechanical activation of all samples. With the peak height at full width at half maximum from XRD and the Scherrer equation, the size of the activated crystallite samples illustrated that the AFM images were in sound agreement with the Scherrer equation. According to the peaks of the AFM images, the average size of the particles in 30 hours of activation was 24 nm with a normal particle distribution. The ICP analysis demonstrated the presence of tungsten carbide particle impurities after activation from the powder sample impacting with the ball and jar. The greatest reduction in size was after milling for 30 hours.

Oral vs intravenous antibiotic prophylaxis in elective laparoscopic cholecystectomy: an exploratory trial.

INTRODUCTION: The application of perioperative intravenous antibiotic prophylaxis is often considered a necessary routine procedure. The only way to decide whether an antibiotic prophylaxis is necessary in elective gallbladder surgery is to conduct a multicenter randomized trial. The aim of this exploratory trial was to clarify whether an oral application of an antibiotic prophylaxis is a feasible and safe procedure compared to intravenous application. This exploratory trial was conducted prospective randomized, using a double-dummy design. The main target criteria included tolerance, adverse effects, pharmacokinetics, and cost of treatment. MATERIAL AND METHODS: Patients undergoing elective laparoscopic cholecystectomy were randomized double-blinded to an oral or intravenous application group of one antibiotic (gyrase inhibitor) using a double-dummy design. Exclusion criteria were acute cholecystitis, icterus, and choledocholithiasis. In addition to a tolerance analysis, the antibiotic concentration was determined in serum and bile by high-pressure liquid chromatography (HPLC). RESULTS: One hundred fifty one patients (75 patients with oral and 76 with intravenous prophylaxis) were evaluated for the tolerance analysis. Four patients (1 p.o., 3 i.v.) had adverse reactions to the antibiotics. The antibiotic serum concentration was 0.83 mg/l (p.o.) vs 8.44 mg/l (i.v.) before surgery, 0.81 mg/l (p.o.) vs 4.43 mg/l (i.v.) during surgery, and 0.69 mg/l (p.o.) vs 2.77 mg/l (i.v.) after surgery. The bile concentration was higher after oral administration with 9.20 mg/l than after intravenous application with 5.79 mg/l. The costs of medication for intravenous application were 20 times higher than those for oral application. CONCLUSION: The oral application of an antibiotic (gyrase inhibitor) was feasible and safe for perioperative antibiotic prophylaxis in laparoscopic cholecystectomy in this exploratory trial.