RESUMO
Among individuals who tested positive for coronavirus disease 2019, smell and taste sensations were significantly less impaired among children than among adults, in a stepwise manner. Sensory impairment was correlated with recent data of angiotensin-converting enzyme 2 expression in the corresponding age groups. This is the first report to compare sensory impairment in children and adults testing positive for coronavirus disease 2019.
Assuntos
Infecções por Coronavirus/fisiopatologia , Hipestesia/virologia , Peptidil Dipeptidase A/biossíntese , Pneumonia Viral/fisiopatologia , Adolescente , Adulto , Fatores Etários , Enzima de Conversão de Angiotensina 2 , Betacoronavirus/isolamento & purificação , COVID-19 , Criança , Pré-Escolar , Infecções por Coronavirus/enzimologia , Infecções por Coronavirus/epidemiologia , Infecções por Coronavirus/virologia , Humanos , Hipestesia/enzimologia , Hipestesia/fisiopatologia , Israel/epidemiologia , Pandemias , Peptidil Dipeptidase A/metabolismo , Pneumonia Viral/enzimologia , Pneumonia Viral/epidemiologia , Pneumonia Viral/virologia , SARS-CoV-2 , Olfato/fisiologia , Paladar/fisiologia , Adulto JovemRESUMO
We examined the dynamics of coronavirus 2019 (COVID-19) transmission within families. Our investigation demonstrated significantly lower rates of COVID-19 positivity in children compared with adults residing in the same household. Children of 5-17 years of age were 61% and children of 0-4 years of age were 47% less likely to have positive polymerase chain reaction results compared with adults residing in the same household.