RESUMO
The combination of propranolol and pulsed dye laser for the treatment of infantile hemangiomas may be superior to either alone. This case report illustrates the additive effect of propranolol and pulsed dye laser for an infantile hemangioma in a high-risk location. Although thorough clinical trials are needed, combination therapy for infantile hemangiomas may prove to be optimal for efficacy.
Assuntos
Hemangioma Capilar/radioterapia , Doenças do Prematuro/terapia , Lasers de Corante/uso terapêutico , Terapia com Luz de Baixa Intensidade , Síndromes Neoplásicas Hereditárias/radioterapia , Propranolol/uso terapêutico , Neoplasias Vulvares/radioterapia , Terapia Combinada , Feminino , Hemangioma Capilar/tratamento farmacológico , Humanos , Lactente , Recém-Nascido Prematuro , Doenças do Prematuro/tratamento farmacológico , Síndromes Neoplásicas Hereditárias/tratamento farmacológico , Indução de Remissão , Neoplasias Vulvares/tratamento farmacológicoAssuntos
Fatores Imunológicos/uso terapêutico , Ceratose/patologia , Mieloma Múltiplo/tratamento farmacológico , Mieloma Múltiplo/patologia , Talidomida/análogos & derivados , Diagnóstico Diferencial , Humanos , Ceratose/diagnóstico , Lenalidomida , Masculino , Pessoa de Meia-Idade , Talidomida/uso terapêuticoRESUMO
Warts are the most common nail tumor generally caused by human papilloma virus (HPV) 1, 2, 4, 27, and 57. HPV 16 and 18 are associated with malignant transformation to squamous cell carcinoma, while HPV 2 and 7 are associated with "butcher's warts." Current treatments range from topical and intralesional therapies to systemic agents and surgical procedures. Despite the numerous available possibilities for treatment, intralesional bleomycin appears to be the most effective treatment for periungual warts.
Assuntos
Antibióticos Antineoplásicos/uso terapêutico , Bleomicina/uso terapêutico , Criocirurgia/métodos , Doenças da Unha/terapia , Neoplasias Cutâneas/terapia , Verrugas/terapia , Administração Tópica , Humanos , Injeções Intralesionais , PapillomaviridaeRESUMO
Chronic venous ulceration is a common and important medical problem that causes significant morbidity. Venous ulcers are expensive to treat, have substantial economic effects in terms of days of work lost, and adversely impact the patient's quality of life. Relying on evidence allows for a rationale of clinical decision making. The objectives of venous ulcer management include the healing of the ulcer, prevention of recurrence, and improvement of edema. Compression is the cornerstone of venous ulcer therapy. Adjunctive modalities such as surgery, growth factors, grafting, biologic skin substitutes, dressings, and oral medication have differing levels of evidence supporting their use, and may also facilitate the healing process.
