Long-term stability of angle-stable versus conventional locked intramedullary nails in distal tibia fractures.

BACKGROUND: In the last years intramedullary nailing has become the treatment of choice for most displaced diaphyseal tibia fractures. In contrast intramedullary nailing of distal tibia fractures is accompanied by problems like decreased biomechanical stability. Nevertheless the indications for intramedullary nailing have been extended to include even more distal fractures. The purpose of this study was to compare long-term mechanical characteristics of angle-stable versus conventional locked intramedullary nails in the treatment of unstable distal tibia fractures. Therefore, the effect of time on the mechanical properties of biodegradable sleeves was assessed. METHODS: 8 pairs of fresh, frozen porcine tibiae were used. The expert tibial nail (Synthes) was equipped with either three conventional locking screws (CL) or the angle-stable locking system (AS), consisting of a special ASLS screw and a biodegradable sleeve. Biomechanical testing included torsional and axial loading at different time-points over 12 weeks. RESULTS: The AS group showed a significantly higher torsional stiffness at all time-points (at least 60%) compared to the CL group (p < 0.001). The neutral zone was at least 5 times higher in the CL group (p < 0.001). The mean axial stiffness was maximum 10% higher (week 6) in the angle-stable locked group compared to the conventional group. There was no significant change of the torsional mechanical characteristics over the 12 weeks in both groups (p > 0.05). For axial stiffness and range of motion significant differences were found in the AS group. CONCLUSIONS: The angle-stable locking system (ASLS) with the biodegradable sleeve provides significantly higher long-term stability. Especially the differences determined under torsional loading in this study may have clinical relevance. The ASLS permits the potential to decrease complications like secondary loss of reduction and mal-/non-union.

Biomechanical characterization of an osteoporotic artificial bone model for the distal femur.

The treatment of osteoporotic distal femur fractures is still an unsolved problem of trauma surgery. The poor bone stock often leads to secondary loss of reduction and implant failure. Therefore, the development of new implants and their biomechanical testing is essential. In a previous study, we developed and initially characterized an artificial osteoporotic bone model of the distal femur. This follow-up study was performed to characterize this model in a biomechanical comparison. We investigated two different artificial bones: five foam cortical shell (Sawbones) and 10 custom-made artificial femoral condyles. Additionally, eight human femora were used for comparison. For biomechanical testing, two intramedullary nails (distal femur nail (DFN) and supracondylar nail (SCN)) were cyclically axial loaded in an AO 33 C2 unstable distal femoral fracture model. In our testing, the artificial bone showed a decrease in the axial stiffness of 27% for the SCN and 28% for the DFN compared to the human results. Also the number of cycles for a deformation of 2.5 mm was reduced by 55% (SCN) and 62% (DFN). This decrease was homogenous and caused by the relative high bone mineral density of the human specimen used. The modes of failure showed no difference between the artificial and human bones. Our customized artificial bone provides suitable results. In relation to the human bones classified as mildly osteoporotic, we assume that the biomechanical properties match to serve as an osteoporotic bone. Yet, we suggest to check transferability of the results with human material.

The primary stability of angle-stable versus conventional locked intramedullary nails.

PURPOSE: The aim of this study was to compare the initial biomechanical characteristics of the angle-stable locking system for intramedullary nails using the new biodegradable sleeve with conventional locking in the treatment of unstable distal tibial fractures. METHODS: Eight pairs of fresh, frozen porcine tibiae were used for this study. The expert tibial nail (Synthes) was equipped with either conventional locking screws (CL) or the angle-stable locking system (AS). This system consists of a special ASLS screw with a biodegradable sleeve. For this investigation distal tibias (5.5 cm) were used and the nails were locked with three screws in both groups. Biomechanical testing included non-destructive torsional and axial loading. RESULTS: The AS group showed a significantly higher torsional stiffness (70%) compared to the CL group. The range of motion was 0.5 times smaller for the AS constructs. The neutral zone was eight times higher in the CL group (p < 0.001). In axial loading the AS group also showed a 10% higher axial stiffness and a 12% lower range of motion (p < 0.001). CONCLUSION: The angle-stable locking system (ASLS) using a special screw and sleeve locking for intramedullary nails provides a significantly higher primary stability. The differences determined in this study may have clinical relevance particularly for torsional loads. For the new biodegradable angle-stable sleeve we found a comparable stability to the PEEK-based sleeve system. This system has the potential to decrease complications such as secondary loss of reduction and mal-/non-union.

Internal fixation of type-C distal femoral fractures in osteoporotic bone: surgical technique.

BACKGROUND: Fixation of distal femoral fractures remains a challenge, especially in osteoporotic bone. This study was performed to investigate the biomechanical stability of four different fixation devices for the treatment of comminuted distal femoral fractures in osteoporotic bone. METHODS: Four fixation devices were investigated biomechanically under torsional and axial loading. Three intramedullary nails, differing in the mechanism of distal locking (with two lateral-to-medial screws in one construct, one screw and one spiral blade in another construct, and four screws [two oblique and two lateral-to-medial with medial nuts] in the third), and one angular stable plate were used. All constructs were tested in an osteoporotic synthetic bone model of an AO/ASIF type 33-C2 fracture. Two nail constructs (the one-screw and spiral blade construct and the four-screw construct) were also compared under axial loading in eight pairs of fresh-frozen human cadaveric femora. RESULTS: The angular stable plate constructs had significantly higher torsional stiffness than the other constructs; the intramedullary nail with four-screw distal locking achieved nearly comparable results. Furthermore, the four-screw distal locking construct had the greatest torsional strength. Axial stiffness was also the highest for the four-screw distal locking device; the lowest values were achieved with the angular stable plate. The ranking of the constructs for axial cycles to failure was the four-screw locking construct, with the highest number of cycles, followed by the angular stable plate, the spiral blade construct, and two-screw fixation. The findings in the human cadaveric bone were comparable with those in the synthetic bone model. Failure modes under cyclic axial load were comparable for the synthetic and human bone models. CONCLUSIONS: The findings of this study support the concept that, for intramedullary nails, the kind of distal interlocking pattern affects the stabilization of distal femoral fractures. Four-screw distal locking provides the highest axial stability and nearly comparable torsional stability to that of the angular stable plate; the four-screw distal interlocking construct was found to have the best combined (torsional and axial) biomechanical stability.

Evaluation of a polyaxial angle-stable volar plate in a distal radius C-fracture model--a biomechanical study.

INTRODUCTION: Polyaxial angle-stable plating is thought to be particularly beneficial in the management of complex intra-articular fractures of the distal radius. The purpose of the present study was to investigate whether the technique provides stability to match that of conventional (fixed-angle) angle-stable constructs. MATERIAL AND METHODS: In seven pairs of human cadaver radii, an Arbeitsgemeinschaft für Osteosynthese (AO) 23 C2.1 intra-articular fracture was created. One radius of each pair received a juxta-articular 2.4-mm locking compression plate (LCP) Volar Distal Radius Plate, whilst the contralateral one received a 2.4-mm Variable Angle Locking Compression Plate (LCP) Two-Column Volar Distal Radius Plate (both plates: Synthes, Oberdorf, Switzerland). Parameters tested were construct stiffness (static axial loading with 150 N), range of motion and secondary loss of reduction (dynamic 150 N axial loading over 5000 cycles). Stiffness and range of motion were measured both pre- and post-cycling. RESULTS: The polyaxial constructs were significantly stiffer, both before and after cyclic testing. However, the two-column plates showed a significant loss of stiffness during cyclic testing. The range of motion was significantly greater, both initially and at the end of cyclic testing, in the fixed-angle constructs. The conventional constructs had significantly greater secondary loss of reduction. CONCLUSION: The polyaxial two-column plate tested in this study provides a biomechanically sound construct for the management of intra-articular fractures of the distal radius.

Distal femur fractures of the elderly--different treatment options in a biomechanical comparison.

BACKGROUND: Fractures of the distal femur, especially in the elderly patient, are an unsolved problem in orthopaedic and trauma surgery. Poor bone stock quality caused by osteoporosis often results in bad implant anchorage in the distal part with a high risk of secondary failures such as cutout. This study investigates the biomechanical characteristics of four implants with different distal locking options under quasi-static torsional and cyclic axial loading. Therefore, an osteoporotic bone model simulating severe osteoporotic conditions was used. METHODS: Four different implants (T2 intramedullary nail, supracondylar nail (SCN), distal femoral nail (DFN) and the AxSOS angular stable plate) with different distal locking options were instrumented using an osteoporotic bone model. Five specimens per implant and per loading type (torsional and axial) were used. Mechanical testing was performed under physiologic loading conditions. First, a torsional test was performed in internal and external rotation (10 Nm), with a new specimen; a stepwise cyclic axial loading was conducted until failure of the construct. FINDINGS: For torsional loading, the lowest range of motion (ROM) and neutral zone (NZ) was found for the AxSOS plate construct. The SCN and T2 constructs showed similar results, and the highest ROM and NZ were found for the constructs treated with the DFN. Axial stiffness was highest for SCN constructs and in the same range for DFN and T2. The lowest stiffness showed in the AxSOS plate constructs with 47% of SCN stiffness. Under cyclic axial loading, the SCN constructs showed the highest number of cycles to failure, followed by AxSOS (70%), DFN (69%) and T2 (48%). INTERPRETATION: In conclusion of this biomechanical study, we can clinically suggest that, if, in general, torsional stability is required (e.g., for bedridden patients) the AxSOS plate will be sufficient. By contrast, the findings of this study support the fact that the SCN should be considered for mobile patients where early postoperative mobilisation for rehabilitation is desired.

Evaluation of a customized artificial osteoporotic bone model of the distal femur.

In the development of new implants biomechanical testing is essential. Since human bones vary markedly in density and geometry their suitability for biomechanical testing is limited. In contrast artificial bones are of great uniformity and therefore appropriate for biomechanical testing. However, the applied artificial bones have to be proved as comparable to human bone. An anatomical shaped artificial bone representing the distal human femur was created by foaming polyurethane. To get a bone model with properties of osteoporotic bone a foam density of 150 kg/m3 was used. The biomechanical properties of our artificial bones were evaluated against eight mildly osteoporotic fresh frozen human femora by mechanical testing. At the artificial bones all tested parameters showed a very small variation. In contrast significant correlation between bone mass density and tested parameters was found for the human bones. The artificial bones reached 39% of the compression strength and 41% of the screw pullout force of the human bone. In indentation testing the artificial bones reached 27% (cancellous) and 59% (cortical) respectively of the human bones strength. Regarding Shore hardness artificial bone and human bone showed comparable results for the cortical layer and at the cancellous layer the artificial bone reached 57% of human bones hardness. Our described method for customizing of artificial bones regarding their shape and bone stock quality provides suitable results. In relation to the as mildly osteoporotic classified human bones we assume that the biomechanical properties matching to serve osteoporotic bone.

Plantar versus dorsomedial locked plating for Lapidus arthrodesis: a biomechanical comparison.

BACKGROUND: Lapidus arthrodesis with a plate and a compression screw is an established procedure in hallux valgus surgery. The present study was performed to investigate the potential benefit of a compression screw combined with a plantarly applied angle-stable, anatomically precontoured plate or a dorsomedially applied angle-stable plate. METHODS: In six pairs of human cadaver specimens, one specimen each was randomized to receive a dorsomedial H-shaped plate, while the other received a plantar plate. Bone mineral density was measured with peripheral quantitative computed tomography. The specimens were loaded quasi-statically, followed by cyclic loading. Finally, they were loaded to failure. In the static tests, stiffness and range of motion (ROM) data were obtained. In the cyclic tests, the constructs' displacement was studied. In the load-to-failure test, stiffness and maximum load to failure were measured. RESULTS: The two groups did not differ significantly with regard to BMD (p = 0.25). Any significant differences observed were in favor of the plantar constructs, which had greater initial stiffness (p = 0.028) and final stiffness (p = 0.042), a smaller ROM (p = 0.028), and a greater load to failure (p = 0.043). There was no significant difference regarding displacement (p = 0.14). CONCLUSION: In the static tests, the plantar angle-stable plate construct was superior to the dorsomedial angle-stable plate construct. CLINICAL RELEVANCE: Plantar plating appears to offer biomechanical benefit. Clinical studies will be required to show whether this translates into earlier resumption of weightbearing and into lower rates of nonunion.

Choosing a proper working length can improve the lifespan of locked plates. A biomechanical study.

BACKGROUND: It is hypothesized that the working length influences the implants fatigue behavior. However, few studies addressing this issue came to contrary results. Therefore, we tested systematically the influence of working length and implant material on the plate's endurance. METHODS: We used an artificial model providing the substantial angle and length conditions of a human femur. A fracture gap of 10mm was bridged with identical shaped plate implants made of stainless steel and grade-2 titanium. The fatigue strength was tested for a short, medium and long working length. Aiming at an implant failure within 80,000 loading cycles the upper load threshold was set to 265N for the titanium plates and to 420N for the steel plates. The lower load threshold was -20N for both plates. FINDINGS: For the steel plates there was no correlation between fatigue strength and working length. The construct stiffness did not differ at short and medium working length and was reduced by 10% (P=0.047) at long working length. For the titanium plates the fatigue strength tends to increase with the working length but this correlation was not significant (τ=0.417, P=0.051). Further there was a negative correlation between working length and construct stiffness (τ=0.552; P=0.01). INTERPRETATION: The working length has no appreciable effect on the endurance of the steel plates. Compared to the grade 2-titanium plates the stainless steel plates sustain a larger amount of cyclic load. However, for the titanium plates a larger working length tends to improve the endurance.

Internal fixation of type-C distal femoral fractures in osteoporotic bone.

BACKGROUND: Fixation of distal femoral fractures remains a challenge, especially in osteoporotic bone. This study was performed to investigate the biomechanical stability of four different fixation devices for the treatment of comminuted distal femoral fractures in osteoporotic bone. METHODS: Four fixation devices were investigated biomechanically under torsional and axial loading. Three intramedullary nails, differing in the mechanism of distal locking (with two lateral-to-medial screws in one construct, one screw and one spiral blade in another construct, and four screws [two oblique and two lateral-to-medial with medial nuts] in the third), and one angular stable plate were used. All constructs were tested in an osteoporotic synthetic bone model of an AO/ASIF type 33-C2 fracture. Two nail constructs (the one-screw and spiral blade construct and the four-screw construct) were also compared under axial loading in eight pairs of fresh-frozen human cadaveric femora. RESULTS: The angular stable plate constructs had significantly higher torsional stiffness than the other constructs; the intramedullary nail with four-screw distal locking achieved nearly comparable results. Furthermore, the four-screw distal locking construct had the greatest torsional strength. Axial stiffness was also the highest for the four-screw distal locking device; the lowest values were achieved with the angular stable plate. The ranking of the constructs for axial cycles to failure was the four-screw locking construct, with the highest number of cycles, followed by the angular stable plate, the spiral blade construct, and two-screw fixation. The findings in the human cadaveric bone were comparable with those in the synthetic bone model. Failure modes under cyclic axial load were comparable for the synthetic and human bone models. CONCLUSIONS: The findings of this study support the concept that, for intramedullary nails, the kind of distal interlocking pattern affects the stabilization of distal femoral fractures. Four-screw distal locking provides the highest axial stability and nearly comparable torsional stability to that of the angular stable plate; the four-screw distal interlocking construct was found to have the best combined (torsional and axial) biomechanical stability.

How do visual, spectroscopic and biomechanical changes of cartilage correlate in osteoarthritic knee joints?

BACKGROUND: Characteristic changes in cartilage of human knee joints with different degrees of osteoarthritis (OA) have been investigated by visual, biophotonical and biomechanical examination. Knowledge about the cartilage composition and changes during the development of OA is important for diagnostic decisions and understanding the pathogenesis of OA. METHODS: Thirty two patients with severe knee OA received endoprosthetic replacement. During surgical intervention cartilage specimen were harvested from defined surface areas of the joints. The degree of cartilage defects was classified visually (ICRS Grade: International Cartilage Repair Society), biophotonically (NIRS: near infrared spectroscopy) and biomechanically (Young's Modulus). To characterise links between the investigated parameters the Spearman's rank correlation coefficient was used. FINDINGS: Significant negative correlations were found between visual macroscopic degree of degeneration (ICRS Grade) and biophotonic characteristics (NIRS) (rho=-0.467) or cartilage stiffness (Young's Modulus) (rho=-0.501). Between NIRS and Young's Modulus significant positive correlation of rho=0.535 was detected. INTERPRETATION: Visual, biophotonic and biomechanical properties of cartilage reveal strong correlations in all degrees of cartilage defects in patients with severe OA. According to these results, we indicate that an objective, non-invasive and non-destructive measurement of cartilage properties during open and arthroscopic knee surgery is possible by NIRS and provide a novel tool to evaluate disease intervention and treatment.

The strength of polyaxial locking interfaces of distal radius plates.

BACKGROUND: Currently available polyaxial locking plates represent the consequent enhancement of fixed-angle, first-generation locking plates. In contrast to fixed-angle locking plates which are sufficiently investigated, the strength of the new polyaxial locking options has not yet been evaluated biomechanically. This study investigates the mechanical strength of single polyaxial interfaces of different volar radius plates. METHODS: Single screw-plate interfaces of the implants Palmar 2.7 (Königsee Implantate und Instrumente zur Osteosynthese GmbH, Allendorf, Germany), VariAx (Stryker Leibinger GmbH & Co. KG, Freiburg, Germany) und Viper (Integra LifeSciences Corporation, Plainsboro, NJ, USA) were tested by cantilever bending. The strength of 0 degrees, 10 degrees and 20 degrees screw locking angle was obtained during static and dynamic loading. FINDINGS: The Palmar 2.7 interfaces showed greater ultimate strength and fatigue strength than the interfaces of the other implants. The strength of the VariAx interfaces was about 60% of Palmar 2.7 in both, static and dynamic loading. No dynamic testing was applied to the Viper plate because of its low ultimate strength. By static loading, an increase in screw locking angle caused a reduction of strength for the Palmar 2.7 and Viper locking interfaces. No influence was observed for the VariAx locking interfaces. During dynamic loading; angulation had no influence on the locking strength of Palmar 2.7. However, reduction of locking strength with increasing screw angulation was observed for VariAx. INTERPRETATION: The strength of the polyaxial locking interfaces differs remarkably between the examined implants. Depending on the implant an increase of the screw locking angle causes a reduction of ultimate or fatigue strength, but not in all cases a significant impact was observed.

Biomechanical evaluation of plate osteosynthesis of distal fibula fractures with biodegradable devices.

BACKGROUND: This study compared fixation with a titanium one-third tubular plate and one lag-screw vs. fixation with biodegradable plates with one lag-screw applied with two different plate-screw patterns. MATERIALS AND METHODS: Ten pairs of fibulas were osteotomied, plated (titanium plate with one lag screw vs. absorbable 2/8 plate-screws crossing vs. 0/8 plate-screws crossing the osteotomy gap). and tested in torsion and bending to obtain stiffness and neutral-zone (NZ) data. Tests were performed using 5 load cycles. No load to failure was performed. Biodegradation was simulated by 6 week immersion in phosphate-buffered saline after which the testing protocol was repeated. The specimens were then loaded with 100 N in bending. RESULTS: Post-implantation, there were no significant differences, in torsion and bending, regarding the NZ or the stiffness, between the 2/8 biodegradable plate and the titanium plate. The 0/8 pattern performed significantly less well in terms of stiffness and NZ in the initial torsion test, and significantly less well in terms of stiffness in the initial bending test. After 6 weeks' immersion, all biodegradable constructs showed a significantly larger NZ and significantly reduced bending and torsional stiffness. When loaded with 100 N, four of the six 0/8 osteosyntheses failed. There were no significant differences between the 2/8 pattern and the titanium plates. CONCLUSION: In a model of a Weber-B fracture, the use of a 2/8 biodegradable plate construct initially did not differ statistically to that obtained with a one-third tubular titanium plate. After immersion the 2/8 construct withstood some physiological load. CLINICAL RELEVANCE: For the fixation of ankle fractures with a biodegradable plate of the type employed in this study, the use of fracture-gap-crossing screws is recommended.

Temperature influence on DXA measurements: bone mineral density acquisition in frozen and thawed human femora.

BACKGROUND: Determining bone mineral density (BMD) with dual-energy x-ray absorptiometry (DXA) is an established and widely used method that is also applied prior to biomechanical testing. However, DXA is affected by a number of factors. In order to delay decompositional processes, human specimens for biomechanical studies are usually stored at about -20 degrees C; similarly, bone mineral density measurements are usually performed in the frozen state. The aim of our study was to investigate the influence of bone temperature on the measured bone mineral density. METHODS: Using DXA, bone mineral density measurements were taken in 19 fresh-frozen human femora, in the frozen and the thawed state. Water was used to mimic the missing soft tissue around the specimens. Measurements were taken with the specimens in standardized internal rotation. Total-BMD and single-BMD values of different regions of interest were used for evaluation. RESULTS: Fourteen of the 19 specimens showed a decrease in BMD after thawing. The measured total-BMD of the frozen specimens was significantly (1.4%) higher than the measured BMD of the thawed specimens. CONCLUSION: Based on our findings we recommend that the measurement of bone density, for example prior to biomechanical testing, should be standardized to thawed or frozen specimens. Temperature should not be changed during measurements. When using score systems for data interpretation (e.g. T- or Z-score), BMD measurements should be performed only on thawed specimens.

Angle-stable and compressed angle-stable locking for tibiotalocalcaneal arthrodesis with retrograde intramedullary nails. Biomechanical evaluation.

BACKGROUND: Retrograde intramedullary nailing is an established procedure for tibiotalocalcaneal arthrodesis. The goal of this study was to evaluate the effects of angle-stable locking or compressed angle-stable locking on the initial stability of the nails and on the behavior of the constructs under cyclic loading conditions. METHODS: Tibiotalocalcaneal arthrodesis was performed in fifteen third-generation synthetic bones and twenty-four fresh-frozen cadaver legs with use of retrograde intramedullary nailing with three different locking modes: a Stryker nail with compressed angle-stable locking, a Stryker nail with angle-stable locking, and a statically locked Biomet nail. Analyses were performed of the initial stability of the specimens (range of motion) and the laxity of the constructs (neutral zone) in dorsiflexion/plantar flexion, varus/valgus, and external rotation/internal rotation. Cyclic testing up to 100,000 cycles was also performed. The range of motion and the neutral zone in dorsiflexion/plantar flexion at specific cycle increments were determined. RESULTS: In both bone models, the intramedullary nails with compressed angle-stable locking and those with angle-stable locking were significantly superior, in terms of a smaller range of motion and neutral zone, to the statically locked nails. The compressed angle-stable nails were superior to the angle-stable nails only in the synthetic bone model, in external/internal rotation. Cyclic testing showed the nails with angle-stable locking and those with compressed angle-stable locking to have greater stability in both models. In the synthetic bone model, compressed angle-stable locking was significantly better than angle-stable locking; in the cadaver bone model, there was no significant difference between these two locking modes. During cyclic testing, five statically locked nails in the cadaver bone model failed, whereas one nail with angle-stable locking and one with compressed angle-stable locking failed. CONCLUSIONS: Regardless of the bone model, the nails with angle-stable or compressed angle-stable locking had better initial stability and better stability following cycling than did the nails with static locking.

Biomechanical evaluation of primary stiffness of tibiotalocalcaneal fusion with intramedullary nails.

BACKGROUND: Intramedullary implants are being used with increasing frequency for tibiotalocalcaneal fusion (TTCF). Clinically, the question arises whether intramedullary (IM) nails should have a compression mode to enhance biomechanical stiffness and fusion-site compression. This biomechanical study compared the primary stability of TTCF constructs using compressed and uncompressed retrograde IM nails and a screw technique in a bone model. METHODS: For each technique, three composite bone models were used. The implants were a Biomet nail (static locking mode and compressed mode), a T2 femoral nail (compressed mode); a prototype IM nail 1 (PT1, compressed mode), a prototype IM nail 2 (PT2, dynamic locking mode and compressed mode), and a three-screw construct. The compressed contact surface of each construct was measured with pressure-sensitive film and expressed as percent of the available fusion-site area. Stiffness was tested in dorsiflexion and plantarflexion (D/P), varus and valgus (V/V), and internal rotation and external rotation (I/E) (20 load cycles per loading mode). RESULTS: Mean contact surfaces were 84.0 +/- 6.0% for the Biomet nail, 84.0 +/- 13.0% for the T2 nail, 70.0 +/- 7.2% for the PTI nail, and 83.5 +/- 5.5% for the compressed PT2 nail. The greatest primary stiffness in D/P was obtained with the compressed PT2, followed by the compressed Biomet nail. The dynamically locked PT2 produced the least primary stiffness. In V/V, PT1 had the (significantly) greatest primary stiffness, followed by the compressed PT2. The statically locked Biomet nail and the dynamically locked PT2 had the least primary stiffness in V/V. In I/E, the compressed PT2 had the greatest primary stiffness, followed by the PT1 and the T2 nails, which did not differ significantly from each other. The dynamically locked PT2 produced the least primary stiffness. The screw construct's contact surface and stiffness were intermediate. CONCLUSIONS: The IM nails with compression used for TTCF produced good contact surfaces and primary stiffness. They were significantly superior in these respects to the uncompressed nails and the screw construct. The large contact surfaces and great primary stiffness provided by the IM nails in a bone model may translate into improved union rates in patients who have TTCF.