Vicarious punishment of moral violations in naturalistic drama narratives predicts cortical synchronization.

Punishment of moral norm violators is instrumental for human cooperation. Yet, social and affective neuroscience research has primarily focused on second- and third-party norm enforcement, neglecting the neural architecture underlying observed (vicarious) punishment of moral wrongdoers. We used naturalistic television drama as a sampling space for observing outcomes of morally-relevant behaviors to assess how individuals cognitively process dynamically evolving moral actions and their consequences. Drawing on Affective Disposition Theory, we derived hypotheses linking character morality with viewers' neural processing of characters' rewards and punishments. We used functional magnetic resonance imaging (fMRI) to examine neural responses of 28 female participants while free-viewing 15 short story summary video clips of episodes from a popular US television soap opera. Each summary included a complete narrative structure, fully crossing main character behaviors (moral/immoral) and the consequences (reward/punishment) characters faced for their actions. Narrative engagement was examined via intersubject correlation and representational similarity analysis. Highest cortical synchronization in 9 specifically selected regions previously implicated in processing moral information was observed when characters who act immorally are punished for their actions with participants' empathy as an important moderator. The results advance our understanding of the moral brain and the role of normative considerations and character outcomes in viewers' engagement with popular narratives.

Cognitive and perceptual load have opposing effects on brain network efficiency and behavioral variability in ADHD.

Attention-deficit/hyperactivity disorder (ADHD) is a highly prevalent neurodevelopmental disorder associated with suboptimal outcomes throughout the life-span. Extant work suggests that ADHD-related deficits in task performance may be magnified under high cognitive load and minimized under high perceptual load, but these effects have yet to be systematically examined, and the neural mechanisms that undergird these effects are as yet unknown. Herein, we report results from three experiments investigating how performance in ADHD is modulated by cognitive load and perceptual load during a naturalistic task. Results indicate that cognitive load and perceptual load influence task performance, reaction time variability (RTV), and brain network topology in an ADHD-specific fashion. Increasing cognitive load resulted in reduced performance, greater RTV, and reduced brain network efficiency in individuals with ADHD relative to those without. In contrast, increased perceptual load led to relatively greater performance, reduced RTV, and greater brain network efficiency in ADHD. These results provide converging evidence that brain network efficiency and intraindividual variability in ADHD are modulated by both cognitive and perceptual load during naturalistic task performance.

Moral foundations elicit shared and dissociable cortical activation modulated by political ideology.

Moral foundations theory (MFT) holds that moral judgements are driven by modular and ideologically variable moral foundations but where and how these foundations are represented in the brain and shaped by political beliefs remains an open question. Using a moral vignette judgement task (n = 64), we probed the neural (dis)unity of moral foundations. Univariate analyses revealed that moral judgement of moral foundations, versus conventional norms, reliably recruits core areas implicated in theory of mind. Yet, multivariate pattern analysis demonstrated that each moral foundation elicits dissociable neural representations distributed throughout the cortex. As predicted by MFT, individuals' liberal or conservative orientation modulated neural responses to moral foundations. Our results confirm that each moral foundation recruits domain-general mechanisms of social cognition but also has a dissociable neural signature malleable by sociomoral experience. We discuss these findings in view of unified versus dissociable accounts of morality and their neurological support for MFT.

Reproducing FSL's fMRI data analysis via Nipype: Relevance, challenges, and solutions.

The "replication crisis" in neuroscientific research has led to calls for improving reproducibility. In traditional neuroscience analyses, irreproducibility may occur as a result of issues across various stages of the methodological process. For example, different operating systems, different software packages, and even different versions of the same package can lead to variable results. Nipype, an open-source Python project, integrates different neuroimaging software packages uniformly to improve the reproducibility of neuroimaging analyses. Nipype has the advantage over traditional software packages (e.g., FSL, ANFI, SPM, etc.) by (1) providing comprehensive software development frameworks and usage information, (2) improving computational efficiency, (3) facilitating reproducibility through sufficient details, and (4) easing the steep learning curve. Despite the rich tutorials it has provided, the Nipype community lacks a standard three-level GLM tutorial for FSL. Using the classical Flanker task dataset, we first precisely reproduce a three-level GLM analysis with FSL via Nipype. Next, we point out some undocumented discrepancies between Nipype and FSL functions that led to substantial differences in results. Finally, we provide revised Nipype code in re-executable notebooks that assure result invariability between FSL and Nipype. Our analyses, notebooks, and operating software specifications (e.g., docker build files) are available on the Open Science Framework platform.

The extended Moral Foundations Dictionary (eMFD): Development and applications of a crowd-sourced approach to extracting moral intuitions from text.

Moral intuitions are a central motivator in human behavior. Recent work highlights the importance of moral intuitions for understanding a wide range of issues ranging from online radicalization to vaccine hesitancy. Extracting and analyzing moral content in messages, narratives, and other forms of public discourse is a critical step toward understanding how the psychological influence of moral judgments unfolds at a global scale. Extant approaches for extracting moral content are limited in their ability to capture the intuitive nature of moral sensibilities, constraining their usefulness for understanding and predicting human moral behavior. Here we introduce the extended Moral Foundations Dictionary (eMFD), a dictionary-based tool for extracting moral content from textual corpora. The eMFD, unlike previous methods, is constructed from text annotations generated by a large sample of human coders. We demonstrate that the eMFD outperforms existing approaches in a variety of domains. We anticipate that the eMFD will contribute to advance the study of moral intuitions and their influence on social, psychological, and communicative processes.