[The feeding of newborns with low birth weight with milk formula "Nenatal" and "Nutrilon-premium"].

The aim of the study is to make retrospective analysis of 9 years experience in the feeding of praematuries and high risk newborn in that ward in First City Hospital-Sofia with formula milks "Nenatal" and "Nutrilon-premium". 721--42.4% from all babies in this period were feed with those formulas. With Nenatal only--11.8%, with Nutrilon-premium 88.2%. This the fact is due that all babies under 2000 gr. were fed with Nenatal, and after reaching 2000 gr.--with Nutrilon-premium. The results confirm that Nenatal is right formula for feeding of low and very low birth weight infant, due to its special content and qualities. The results from Nutrilon-premium illustrated that mean gain weight is the biggest in I grade of prematurity--33 grams, followed by matures--30 gr, after them II grade--29 gr., III grade--27 gr., IV grade--26 gr. As a conclusion we may say that mean gain weight for all groups is 29 grams. Consuming all gain weight of the babies feeding with Nutrilon-premium data appear that the biggest is in III of prematurity--1499 grams, followed by IV grade--1418 gr., I grade--1341 spama, II grade--1219 gr., and last matures--745 gr.

[Alpha-2 macroglobulin in serum and synovial fluid of patients with rheumatoid arthritis and osteoarthrosis]. / Alpha2-makroglobulin v syvorotke i sinovial'noi zhidkosti bol'nykh revmatoidnym artritom i osteoartrozom.

AIM: To study concentrations of alpha-2-macroglobulin (A-2-MG) in blood serum and synovial fluid (SF) in patients with rheumatoid arthritis and formulation of basic clinical, laboratory and x-ray criteria of RA activity. MATERIALS AND METHODS: A-2-MG levels were measured in the serum and SF from 151 RA patients and in the serum of 20 patients with osteoarthrosis (OA) and 62 healthy donors. The serum concentration for RA patients was 166 +/- 65.3 mg%, for OA patients--175.26 +/- 36.99 mg% and for healthy donors--177.772 +/- 50 mg%. Mean concentration of SF A-2-MG in RA patients was 98.77 +/- 82.43 mg%. CONCLUSION: Changes in the concentration of A-2-MG are unrelated to inflammation activity in the joints of RA and OA patients. Serum and synovial concentration of this protein corresponds to changes in the concentration of IgM and rheumatoid factors in RA patients.

[The evaluation of energy balance in pregnancy]. / Otsenka na energiiniia balans pri bremennost.

Energy balance assessment of 317 pregnant women in Sofia was conducted. Energy intake and energy expenditure during the first and the third trimester, gestational weight gain and prepregnancy body mass index have been studied. The regression analysis revealed a significant correlation between neonate body mass and energy expenditure level, but the decreased metabolic constants of physical activity, suggested an influence of increased basal metabolic rate, corresponding to the gestational body mass gain.

[The effect of the diet on the iron status and incidence of anemia in pregnant women]. / Vuzdeistvie na dietata vurkhu zhelezniia status i chestotata na anemiia pri bremenni zheni.

The influence of dietary intakes during I and III trimester of pregnancy on iron status and anemia incidence [correction of prevalence] in 44 healthy pregnant women were studied. For evaluation of iron intake the probability approach calculations were used. Iron status was assessed by using multiple criteria--iron in serum, TIBC, transferrin saturation capacity and hemoglobin level. Iron deficient anemia is diagnosed in pregnant woman when hemoglobin level is less than 110 g/l and the least two of the other indices are abnormal. More than 70% of the women studied have low dietary intake of iron during pregnancy, but only 21% are anemic. The half of women with anemia are with iron deficient anemia. The results of iron intake may overestimate the risk of developing iron deficiency. Iron status during pregnancy is influenced by the dietary intake and diet structure, iron body stores and adaptive mechanisms.