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1.
Antibiotics (Basel) ; 12(5)2023 Apr 30.
Artigo em Inglês | MEDLINE | ID: mdl-37237737

RESUMO

Antimicrobial stewardship programs (AMSPs) are essential elements in reducing the unnecessary overprescription of antibiotics. Most of the actions of these programs have focused on actions during acute hospitalization. However, most prescriptions occur after hospital discharge, which represents a necessary and real opportunity for improvement in these programs. We present an AMSP multifaceted strategy implemented in a surgical department which was carried out by a multidisciplinary team to verify its reliability and effectiveness. Over a 1-year post-implementation period, compared to the pre-intervention period, a significant reduction of around 60% in antibiotic exposure occurred, with lower economic cost and greater safety.

6.
Ann Otol Rhinol Laryngol ; 128(11): 1078-1080, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-31204488

RESUMO

OBJECTIVES: Inflammatory myofibroblastic tumor (IMT) is a rare benign lesion, especially in the pediatric age. There are several cases described in pulmonary, digestive and renal localizations, but involvement in head and neck area is infrequent. METHODS: Case report and review of the literature. RESULTS: A 1 year and 11 months old child, during 2 months had clinical signs of nasal respiratory insufficiency and epistaxis subsequently developing a purulent rhinorrhea and a sleep apnea. His pediatrician previously requested a sinus and cavum X-ray with the finding of an image compatible with an intranasal mass. Endoscopic resection was performed of the mass with further immunohistochemical analysis showing the result of a lesion compatible with IMT. CONCLUSIONS: Even though there are very few cases in scientific literature of a tumor with these characteristics in infants, IMT must be present as a differential diagnosis of intranasal masses. The role of the pathologist is essential to reach the definitive diagnosis and the performance of an early surgical treatment decreases aesthetic consequences in this pathology.


Assuntos
Endoscopia/métodos , Epistaxe/etiologia , Cavidade Nasal/patologia , Neoplasias de Tecido Muscular/diagnóstico , Neoplasias dos Seios Paranasais/diagnóstico , Seios Paranasais/diagnóstico por imagem , Diagnóstico Diferencial , Epistaxe/diagnóstico , Humanos , Lactente , Imageamento por Ressonância Magnética , Masculino , Neoplasias de Tecido Muscular/complicações , Neoplasias de Tecido Muscular/cirurgia , Neoplasias dos Seios Paranasais/complicações , Neoplasias dos Seios Paranasais/cirurgia , Tomografia Computadorizada por Raios X
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