Design and analysis of a highly sensitive SPR based PCF biosensor with double step dual peak shift sensitivity.

This paper introduces a comprehensive study of a quad-cluster multi-functional Photonic Crystal Fiber (PCF) sensor where gold and Aluminum doped with zinc oxide (AZO) were used as plasmonic materials. A maximum Amplitude Sensitivity (AS) of 5336 RIU-1 and Wavelength Sensitivity (WS) of 40,500 nm/RIU in y pol was obtained incorporating Gold as plasmonic material. When AZO was included as the plasmonic material, AS of 3763 RIU-1 & WS of 9100 nm/RIU for y polarization were determined. The RI detecting range was increased from 1.32 to 1.43 to 1.19-1.42 after using AZO instead of Au that opens up a new horizon for detection. A novel detection technique, 'Double Step Dual Peak Shift Sensitivity (DS-DPSS)' was proposed in sensing temperature where highest sensitivity of 1.05 nm/°C having resolution of 0.095 °C for x pol. was achieved. Due to its diverse functionality, the suggested sensor represents a significant advancement in the detection of numerous analytes in biochemical applications.

Immobilisation of extra-articular distal radius fractures (Colles type) in dorsiflexion. The functional and anatomical outcome.

BACKGROUND: Cast immobilisation after successful closed reduction is a standard treatment for displaced extra-articular fractures of lower end radius. The position of the wrist during immobilisation is controversial. Immobilisation in dorsiflexion prevents redisplacement after closed reduction. Our aim is to determine the effectiveness of immobilization of wrist in dorsiflexion in such cases and evaluate anatomical and functional outcome. MATERIALS AND METHODS: Study included 54 patients, above 19 years of age with closed extra-articular fractures of lower end radius treated conservatively with below elbow cast application. The wrist was maintained in 15° of dorsiflexion during plaster immobilisation. At 24 weeks, functional results were evaluated with subjective symptoms and objective signs, as per modified Demerit Point Score System. Anatomical result was evaluated based on the scheme devised by Lidstrom (1959) and modified by Sarmiento et al. (1980). RESULTS: 76% patients had Excellent to Good subjective symptoms. Out of 42 patients that had residual dorsal angulation of less than 10°, 37 had excellent to good functional outcome. 39 of the 43 patients who had loss of radial length less than 6 mm had excellent to good functional outcome. 40 out of 49 patients having loss of radial angulation less than 9° showed excellent to good functional outcome. Functional result was directly proportional to anatomical outcome. CONCLUSION: Cast immobilization of extra articular fractures of lower end radius with wrist in dorsiflexion prevents re-displacement of the fragments resulting in satisfactory anatomical & functional outcome.