RESUMO
COVID-19 has changed the global health system and has great impact on different types of medical specialties including, dermatology and rheumatology. This point is important because although these two specialties are distinct subfields of medicine, there is some overlap between them. The overlap can be described by a number of rheumatic diseases that have cutaneous manifestations and vice versa. A good example of this is psoriatic arthritis because, in up to 42% of people, cutaneous lesions and arthritis coexist. Interestingly, emerging reports have described the possible occurrence of psoriasis and psoriatic arthritis in COVID-19 patients. Although the exact mechanism is unclear, some common pathophysiological mechanisms may contribute to disease pathogenesis. Therefore, elucidation of shared pathological pathways that connect these diseases will be valuable for better diagnosis and the complete treatment of COVID-19 patients with cutaneous and rheumatologic diseases.
Assuntos
Artrite Psoriásica , COVID-19 , Dermatologia , Psoríase , Reumatologia , Humanos , Artrite Psoriásica/complicações , Reumatologistas , Dermatologistas , COVID-19/complicaçõesRESUMO
How to cite this article: Jadali Z. Neurological Adverse Events Associated with COVID-19 Vaccination. Indian J Crit Care Med 2023;27(2):154-155.
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BACKGROUND: The purpose of present study was to investigate mitochondrial DNA copy number (mtDNAcn) and mtDNA damage in peripheral blood of patients with Hashimoto's thyroiditis (HT) and healthy controls (HC). METHODS: The relative mtDNAcn and oxidative DNA damage in this case-control study were measured in peripheral blood of 50 patients with Hashimoto's thyroiditis and 50 healthy controls using quantitative real-time PCR. The study was conducted in Tehran University of Medical Sciences hospital, Tehran, Iran in 2018. RESULTS: HT patients had significantly higher mitochondrial DNA copy number and mitochondrial oxidative damage than the comparison group. CONCLUSION: These data suggest the possible involvement of mitochondria and oxidative stress in the pathophysiology of HT.
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There is no abstract.
Assuntos
COVID-19 , Saúde da Criança , Índice de Gravidade de Doença , Adolescente , Adulto , Fatores Etários , COVID-19/epidemiologia , Criança , Humanos , Incidência , Fatores de Risco , SARS-CoV-2RESUMO
No abstract.