1.
Org Lett
; 9(17): 3241-3, 2007 Aug 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17645346
RESUMO
A concise enantiospecific synthesis of (-)-bakkenolide III was accomplished from (S)-(+)-carvone. The key step involved radical cyclization of an iodoketone intermediate which afforded the cis-hydrindanone skeleton. Further synthetic transformations generated bakkenolide III, which also constitutes the formal total synthesis of (-)-bakkenolides, B, C, H, L, V, and X.