RESUMO
Resumen. Objetivo. Este estudo teve como objetivo identificar as características teóricas e metodológicas, assim como os resultados de estudos empíricos, que abordaram a socialização parental da emoção em diversos grupos culturais não ocidentais. Método. Para isso, foi realizada uma revisão integrativa da literatura com um enfoque qualitativo. Resultados. Os resultados mostraram que as principais abordagens teóricas foram os enfoques ecológicos e o modelo heurístico da socialização das emoções. Quanto à metodologia, prevaleceram os estudos quantitativos com maior presença de mães. Os principais resultados salientam que existem variações na socialização da emoção em diversos aspectos, como no funcionamento das crianças, expressão emocional, reação às emoções das crianças, etnoteorias parentais, narrativa emocional e outros. São discutidas as implicações dessas descobertas para futuras pesquisas.
Abstract. Objective. This study aimed to identify the theoretical and methodological characteristics, as well as the results of empirical studies that addressed the parental socialization of emotions in different non-western cultural groups. Method. This required an integrative literature review with a qualitative focus. Results. The results showed that the main theoretical approaches were the ecological approaches and the heuristic model of the socialization of emotions. Regarding employed methodologies, quantitative studies with a greater presence of mothers prevailed. The main results point out that there are variations in the socializing emotions in several aspects such as the functioning of children, emotional expression, reaction to children's emotions, parental ethnotheories, emotional talk and others. Discussion focuses on the implications of these findings for future research.
RESUMO
Aptamers are synthetic single-stranded oligonucleotides (such as RNA and DNA) evolved in vitro using Systematic Evolution of Ligands through Exponential enrichment (SELEX) techniques. Aptamers are evolved to have high affinity and specificity to targets; hence, they have a great potential for use in therapeutics as delivery agents and/or in treatment strategies. Aptamers can be chemically synthesized and modified in a cost-effective manner and are easy to hybridize to a variety of nano-particles and other agents which has paved a way for targeted therapy and diagnostics applications such as in breast tumors. In this review, we systematically explain different aptamer adoption approaches to therapeutic or diagnostic uses when addressing breast tumors. We summarize the current therapeutic techniques to address breast tumors including aptamer-base approaches. We discuss the next aptamer-based therapeutic and diagnostic approaches targeting breast tumors. Finally, we provide a perspective on the future of aptamer-based sensors for breast therapeutics and diagnostics. In this section, the therapeutic applications of aptamers will be discussed for the targeting therapy of breast cancer.