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1.
Sci Rep ; 14(1): 9814, 2024 Apr 29.
Artigo em Inglês | MEDLINE | ID: mdl-38684713

RESUMO

Advanced instruments and methods need to be developed now to create a technical basis to support the negotiation of future nuclear arms control treaties. One new capability that is anticipated is the ability to confirm either the declared presence or declared absence of high explosive (HE) material in the presence of special nuclear material (SNM). Towards this goal, Passive HE Neutron Inspection (PHENIX) has been developed and demonstrated as a method for confirming the presence or absence of HE in the presence of plutonium. The method exploits the inherent presence of neutrons associated with the decay of plutonium as an internal probe source for performing prompt gamma-ray neutron activation analysis (PGNAA), searching for the presence of HE as revealed by the emission of characteristic gamma rays following neutron absorption in hydrogen and nitrogen which are building blocks of present-day, military-grade HE. Tests using stoichiometrically-correct hemishells of mock HE with plutonium show that a system can be expected to positively confirm the presence or absence of these signatures, supporting determination of HE presence or absence with Pu, in a few hours. To protect other potentially sensitive gamma-ray signatures from a treaty accountable item, an analog information barrier has been conceptualized and tested which physically prevents the collection of gamma-ray spectral data outside of user selected energy windows strategically chosen to view only narrow spectral regions corresponding to the hydrogen (2223.2 keV) and nitrogen (9807.2 keV, 10,318.2 keV, and 10,829.2 keV) PGNAA signatures.

2.
Animals (Basel) ; 11(8)2021 Aug 07.
Artigo em Inglês | MEDLINE | ID: mdl-34438790

RESUMO

Bait is often used to increase wildlife harvest susceptibility, enhance viewing opportunities, and survey wildlife populations. The effects of baiting depend on how bait influences space use and resource selection at multiple spatial scales. Although telemetry studies allow for inferences about resource selection within home ranges (third-order selection), they provide limited information about spatial variation in density, which is the result of second-order selection. Recent advances in spatial capture-recapture (SCR) techniques allow exploration of second- and third-order selection simultaneously using non-invasive methods such as camera traps. Our objectives were to describe how short-term baiting affects white-tailed deer (Odocoileus virginianus) behavior and distribution. We fit SCR models to camera data from baited and unbaited locations in southwestern Georgia to assess the effects of short-term baiting on second- and third-order selection of deer during summer and winter surveys. We found little evidence of second-order selection during late summer or early winter surveys when camera surveys using bait are typically conducted. However, we found evidence for third-order selection, indicating that resource selection within home ranges is affected. Concentrations in space use resulting from baiting may enhance disease transmission, change harvest susceptibility, and potentially bias the outcome of camera surveys using bait.

3.
Appl Radiat Isot ; 142: 151-159, 2018 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-30312941

RESUMO

Observations of photon and neutron background radiation were made in Rigby, Idaho, during the Great American Eclipse on August 21, 2017. Photon measurements were made using a mechanically-cooled, high-purity germanium gamma-ray spectrometer, segmenting the data into four energy bands of < 1 MeV, 1-2 MeV, 2-3 MeV, and 3-7 MeV. Neutron measurements were made using 3He proportional counter arrays embedded in polyethylene, either bare or wrapped with Cd or B filters. All data was analyzed in 900-s intervals starting one day before the eclipse and extending to one day after the eclipse. More detailed analyses were made in 90-s intervals for the photon data and 110-s intervals for the neutron data. Meteorological data was simultaneously recorded in 60-s intervals, recording solar radiance, temperature, air pressure, relative humidity, and dew point. For the observations described here, no statistically-significant (> 3σ) variations in signal count rates were observed in either the photon or neutron data. This level corresponds to the lack of observed photon variations exceeding 2.1%, 12.2%, 21.6%, or 43.2% of mean values in the four photon energy groups, respectively; it corresponds to a lack of observed neutron variations exceeding 25.3%, 25.6%, or 16.1% of mean values in the three neutron detector arrays, respectively.

4.
J Am Diet Assoc ; 103(10): 1357-9, 2003 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-14520258

RESUMO

Many healthcare professionals support the idea that weight control and healthy eating should be emphasized early in a person's life to prevent obesity during middle and older adulthood. Unfortunately, although many weight loss programs are available to consumers, few are successful. Recently, constructs of behavioral theories have been integrated into weight loss programs and used to promote changes in health behaviors. In this study, methods used to increase self-efficacy for weight loss were incorporated into a 12-week program designed for weight loss promotion in young adults. Results found that as self-efficacy improved, eating habits improved and weight loss was greater. This study supports the hypothesis that using behavioral techniques to improve self-efficacy can be effective in weight loss promotion and can produce positive outcomes.


Assuntos
Comportamento Alimentar/psicologia , Obesidade/psicologia , Autoeficácia , Redução de Peso , Adolescente , Adulto , Terapia Comportamental , Feminino , Promoção da Saúde , Humanos , Masculino , Obesidade/terapia , Valor Preditivo dos Testes , Autoimagem , Resultado do Tratamento
5.
Biomed Sci Instrum ; 39: 408-14, 2003.
Artigo em Inglês | MEDLINE | ID: mdl-12724928

RESUMO

Breast cancer is currently the third most common cause of cancer in the world. Circulating tumor antigens are often used as a minimally invasive tool for noting breast cancer progression. The objective of this study was to compare four tumor antigens (CA 15-3, CA 27.29, alpha-fetoprotein [AFP], and carcinoembryonic antigen [CEA]) for their diagnostic efficacy in breast cancer patients. It was hypothesized that CA 15-3 would proved to be superior to CA 27.29, CEA, and AFP in assay performance. Tumor marker assays were performed according to the manufacturers' directions. Assays used in this study were CA 15-3 and CA 27.29 (Fujirebio Diagnostics/Centocor Inc.), AFP (Abbott Inc.), and CEA (Hybritech Inc.). A total of 554 patient samples were obtained from an area hospital, plus 200 healthy adult samples which were used for the determination of normal reference intervals. The patients included patients with no disease (184), with non-malignant disease (11), with breast cancer (87), and with other types of cancer (272). Diagnostic percent sensitivities for each marker were: CA 15-3 (63%), CA 27.29 (39%), CEA (22%), and AFP (22%). Diagnostic specificities for each marker were comparable, ranging from 80-88%. Analytical parameters were evaluated for the assays and compared favorably. We concluded that CA 15-3 was the best tumor antigen for use as a diagnostic aid and monitoring agent.


Assuntos
Antígenos de Neoplasias/sangue , Biomarcadores Tumorais/sangue , Neoplasias da Mama/sangue , Neoplasias da Mama/diagnóstico , Programas de Rastreamento/métodos , Técnicas de Sonda Molecular/normas , Adolescente , Adulto , Idoso , Antígenos Glicosídicos Associados a Tumores/sangue , Antígeno Carcinoembrionário/sangue , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Mucina-1/sangue , Valores de Referência , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Método Simples-Cego , Estatística como Assunto , alfa-Fetoproteínas/análise
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