RESUMO
Study of lipid peroxidation (LPO) processes and antioxidant defense (AOD) system of the blood in 96 patients with psychotropic drug poisoning of different severity showed disorders in the LPO/AOD system irrespective of the initial level of chemical injury. These disorders are characterized by imbalance in the ratio of LPO and AOD components. The severity and direction of these disorders depend on the severity of intoxication and poison exposure in the body before treatment measures, which dictates correction of these disorders with consideration for individual LPO and AOD parameters.
Assuntos
Antioxidantes , Peroxidação de Lipídeos , Intoxicação/diagnóstico , Psicotrópicos/intoxicação , Doença Aguda , Adolescente , Adulto , Humanos , Pessoa de Meia-Idade , Prognóstico , Índice de Gravidade de DoençaRESUMO
Use of sodium hypochlorite in combined therapy of patients with alcoholic delirium complicating acute poisoning with psychotropic drugs, caustic poisons, alcohol and its surrogates resulted in an appreciable decrease in the duration of alcoholic delirium.
Assuntos
Delirium por Abstinência Alcoólica/terapia , Intoxicação Alcoólica/terapia , Cáusticos/intoxicação , Desinfetantes/uso terapêutico , Intoxicação/terapia , Psicotrópicos/intoxicação , Hipoclorito de Sódio/uso terapêutico , Adulto , Delirium por Abstinência Alcoólica/metabolismo , Intoxicação Alcoólica/complicações , Intoxicação Alcoólica/metabolismo , Feminino , Histamina/sangue , Humanos , Masculino , Pessoa de Meia-Idade , Intoxicação/metabolismo , Serotonina/sangue , Fatores de TempoRESUMO
In order to estimate the informative value of the leukocytic index of intoxication and the neutrophil to lymphocyte ratio in the assessment of the status of children with acute poisonings, the authors analyzed 223 hemograms of 189 children aged 1 to 15 with different types of acute poisonings. The results indicate that these parameters are nonspecific, their values depend on the severity of the patient's status and are unrelated to sex, age, and type of poisoning; a correlation between the concentration of the toxic agent in the blood and hemogram parameters has been confirmed.